Indiana University, Indianapolis
Edward F. Srour, Ph.D., is a Professor of Medicine, Pediatrics, and Microbiology/Immunology at the Indiana University School of Medicine. Dr. Srour directs the Flow Cytometry Resource Facility of the Indiana University Cancer Center. The research program in the laboratory of Dr. Srour focuses on stem cell biology in general.
aIn particular, three areas of interest are pursued,
hematopoietic stem cells, adult stem cells, and cancer stem cells.
Investigations concerning hematopoietic stem cells examine the
relationship between cell cycle status, homing and engraftment of
these cells as well as the impact of the hematopoietic
microenvironment through ontogeny on these properties. Using a murine
model, the laboratory investigates the differentiation and lineage
specification potential of a group of common pluripotent adult stem
cells detected in multiple tissues and the possible utilization of
these cells in tissue repair and regenerative medicine. In
collaboration with other investigators at Indiana University, Dr.
Srour is working on identifying cancer stem cells in breast cancer and
multiple myeloma. In both areas, a major focus is determining the
genetic fingerprint of cancer stem cells and in breast cancer, one of
the goals of this research is to identify the relationship between
putative cancer stem cells and metastasis.
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