I joined the Baker group in fall of 2009 and began my Ph.D. study with a major of Analytical Chemistry. My project is based on Scanning Ion Conductance Microscope (SICM) and using SICM to study ion transport through synthetic and biological membranes. Heterogeneous conductance of individual pores on a porous membrane can be studied with a four-electrode scanning ion conductance microscope (SICM). And conductance of claudin transport was measured with five-electrode Potentiometric Scanning Ion Conductance Microscopy (P-SICM). I received my B.S. in Chemistry major from Zhejiang University and was an exchange student in Hong Kong University of Science and Technology.