Indiana University
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Zach AronZachary D. Aron

Assistant Professor, Chemistry Department

Office: Chemistry A361

Phone: 812/ 856-4862

Email: zaron at indiana.edu

Lab Website

Education

B.S. 1999 Chemistry University of Illinois at Urbana-Champaign.
Ph.D. 2004 University of California at Irvine
Postdoctoral Fellow Harvard Medical School

Research

Studies of how biosynthetic tools and strategies can be used to generate biologically active small molecules; relevant areas include polyketide biosynthesis, enzyme engineering, enzyme mimetics, natural product synthesis and therapeutics discovery. 


Representative Publications

Aron, Z. D.; Fortin, P. D.; Calderone, C. T.; Walsh, C. T. FenF: Servicing the Mycosubtilin Synthetase Assembly Line in Trans. ChemBioChem, 2007, 8, 613-616.

Aron, Z. D.; Dorrestein, P. C.; Blackhall, J. R.; Kelleher, N. L.; Walsh, C. T. Characterization of a New Tailoring Domain in Polyketide Biogenesis: The Amine Transferase Domain of MycA in the Mycosubtilin Gene Cluster. J. Am. Chem. Soc. 2005, 127, 14986-14987.

Aron, Z. D.; Overman, L. E. Stereocontrolled synthesis of Angularly Substituted 1-Aza-bicyclic Rings by Cationic 2-Aza-Cope Rearrangements. Org. Lett. 2005, 7, 913-916.

Aron, Z. D.; Overman, L. E. Total Synthesis and Properties of the Crambescidin Core Zwitterionic Acid and Crambescidin 359. J. Am. Chem. Soc. 2005, 127, 3380-3390.

Aron, Z. D.; Overman, L. E.; Pietraszekiewicz, H.; Valeriote, F. Synthesis and Biological Activity of Crambescidin Analogs. Bioorg. Med. Chem. Lett. 2004, 14, 3445-3449.