Erin E. Carlson

Assistant Professor, Chemistry Department

Office: Simon Hall 200B

Phone: 812/855-3665

Email: carlsone indiana.edu

Education

B.A. 2000 St. Olaf College
Ph.D 2005 University of Wisconsin - Madison
Postdoctoral Fellowship 2008 The Scripps Research Institute

Research

Professor Erin Carlson’s research program focuses on the development and application of advanced chemical biology and systems biology technologies to both define the mechanisms of bacterial development and identify potential therapeutic agents. We are pursuing the development of technologies for natural product discovery including innovative methods for compound isolation, screening, and diversification. We are also utilizing state of the art metabolomic and proteomic methods to map the biochemical pathways associated with bacterial development and antibiotic resistance. Projects in Dr. Carlson's research group are highly multidisciplinary and members will gain expertise in many of the techniques essential to the field of Chemical Biology including organic synthesis, chromatography, mass spectrometry, structure elucidation, proteomics, metabolomics, biochemistry, microbiology, and molecular biology.

Representative Publications

1. Carlson, E. E. and Cravatt, B. F. Enrichment Tags for Enhanced-Resolution Profiling of Hydrophilic Metabolites. J. Am. Chem. Soc. 2007 , 129, 15780-15782.

2. Carlson, E. E. and Cravatt, B. F. Chemoselective Probes for Metabolite Enrichment and Profiling. Nat. Methods, 2007 , 4, 429-435.

3. Carlson, E. E.; May, J. F.; Kiessling, L. L. Chemical Probes of UDP-Galactopyranose Mutase. Chem. Biol. 2006, 13, 825-837.

4. Soltero-Higgin, M.; Carlson E. E.; Phillips, J. H.; Kiessling, L. L. Identification of Inhibitors for UDP-Galactopyranose Mutase. J. Am. Chem. Soc. 2004, 126, 10532-10533.

5. Soltero-Higgin, M.; Carlson, E. E.; Gruber, T. D.; Kiessling, L. L. A Unique Catalytic Mechanism for UDP-Galactopyranose Mutase. Nat. Struc. Mol. Biol. 2004, 11, 539-543.

6. Carlson, E. E. and Kiessling, L. L. Improved Chemical Syntheses of 1- and 5-Deazariboflavin. J. Org. Chem. 2004, 69, 2614-2617.