Pranav Danthi
Assistant Professor
Office: Simon Hall 220B
Phone: 812/856-2449
Email: pdanthi
indiana.edu
Education
Postdoctoral Research: Vanderbilt University, 2003-2008
Ph.D.: University of Arkansas for Medical Sciences, 2003
Research
Viral and Cellular Determinants of Virus-Induced Cell Death and DiseaseRepresentative Publications
Danthi, P*, C. M. Coffey, J. S. L. Parker, T. W .Abel and T. S. Dermody*(2008) Independent regulation of reovirus membrane penetration and apoptosis by the μ1 φ domain. PLoS Pathogens: 4(12): e1000248. *corresponding authors
Danthi, P., T. Kobayashi, G. H. Holm, M. W. Hansberger, T. W. Abel, and T. S. Dermody (2008). Reovirus apoptosis and virulence are regulated by host cell membrane-penetration efficiency. Journal of Virology 82: 161-172.
Holm G.H., J. Zurney, V. Tumilasci, P. Danthi, J. Hiscott, B. Sherry, and T.S. Dermody (2007). RIG-I and IPS-1 augment proapoptotic responses following mammalian reovirus infection via IRF-3. Journal of Biological Chemistry 282: 21953-21961.
Kobayashi T., A. A. R. Antar, K. W. Boehme, P. Danthi, E. A. Eby, K. M. Guglielmi, G. H. Holm, E. M. Johnson, M. S. Maginnis, S. Naik, W. B. Skelton, J. D. Wetzel, G. J. Wilson, J. D. Chappell, and T. S. Dermody (2007). A plasmid-based reverse genetics system for animal double-stranded RNA viruses. Cell Host and Microbe 1: 147-157.
Hansberger, M.W., J.A.Campbell, P. Danthi, P. Arrate, K.N. Pennington, K.B. Marcu, D.W. Ballard and T.S. Dermody (2007). IkB kinase subunits a and g are required for activation of NF-kB and induction of apoptosis by mammalian reovirus. Journal of Virology 81: 1360-1371.
Danthi, P., G. H. Holm, T. Stehle and T. S. Dermody (2006). Reovirus receptors, cell entry, and signaling. In: Pöhlmann, S., and G. Simmons (eds.): Viral Entry into Cells. Landes Bioscience, Georgetown, TX.
Danthi P., M. W. Hansberger, J. A. Campbell, J. C. Forrest and T.S. Dermody (2006). JAM-A-independent, antibody-mediated uptake of reovirus into cells leads to apoptosis. Journal of Virology 80: 1261-70.


