Faculty Publications

Carl Bauer

Chung, Y.H . Masuda, S., & C. E. Bauer. 2007. Purification and reconstitution of PYP-phytochrome (Ppr) with biliverdin and 4-hydroxycinnamic acid. In Two-Component Signaling Systems " edited by Mel Simon, Brian Crane and Alexandrine Bilwes Crane. Methods in Enzymology. 422:184-189

Swem L. R., Swem, D. L., Wu, J.. & C. E. Bauer. 2007. Purification and Assays of Rhodobacter capsulatus RegB-RegA Two Component Signal Transduction System. In Two-Component Signaling Systems " edited by Mel Simon, Brian Crane and Alexandrine Bilwes Crane. Methods in Enzymology. 422: 173-183

Willett, J., J. L. Smart & C. E. Bauer 2007. RegA in Controls Bacteriochlorophyll and Carotenoid Synthesis in Rhodobacter capsulatus . J. Bacteriol. 189, 7765-7773.

Xiong, J., C. E. Bauer & A. Pancholy. 2007. Insight into the heme d 1 biosynthesis pathway in heliobacteria through bioinformatics analysis. Microbiology, 153, 3548-3562

António, M. R. S., D. B. Finkelstein, D. R. Rollo, L. M. Pratt & C. E. Bauer, 2008. A Model environment for early earth planetary history harbors several new deeply divergent microbial divisions Submitted

Setterdahl, A., & C. E. Bauer. 2008. Regulation of Gene Expression in Response to Oxygen Tension. In Purple Photosynthetic Bacteria . Kluwer Academic Press. In Press

Wu, J., & C. E. Bauer. 2008. RegB/RegA, A Global Redox-Responding Two-Component Regulatory System. In, Bacterial Signal Transduction: network and drug targets. Ryutaro Utsumi edt . pp 131-148 , Landes Bioscience Eurekah, Georgetown , TX

Yuan, H., & C. E. Bauer. 2008. PixE promotes Dark Oligomerization of the BLUF Photoreceptor PixD. Proc. Natl Acad. Sci. USA . In Press

Yuan, H., Dragnea, V. & C. E. Bauer. 2008. Fluorescence Quenching by Acrylamide Monitors Conformation Changes of Trp91 in the Signaling State Formation of BLUF Photoreceptor PixD (Slr1694) . Submitted

Joseph Bonanno

Dongmei Xing, Xingcai Sun, Jinhua Li, Miao Cui, Kah Tan-Allen and Joseph A. Bonanno ; Hypoxia preconditioning protects corneal stromal cells against induced apoptosis. Exp Eye Res 2006; 82:780.

Yan Zhang , Jinhua Li, Qiang Xie and Joseph A. Bonanno . Molecular expression and functional involvement of the bovine calcium-activated chloride channel 1 (bCLCA1) in apical HCO 3 - permeability of bovine corneal endothelium Exp Eye Res. 2006 Nov; 83(5):1215-24.

Cheng Q , Nguyen T, Song H , Bonanno J. Hypoxia protects human corneal endothelium from tertiary butyl hydroperoxide and paraquat-induced cell death in vitro. Exp Biol Med (Maywood). 2007 Mar; 232(3):445-53.

Role of Carbonic Anhydrase IV in Corneal Endothelial HCO 3 - Transport. Xing Cai Sun, Jinhua Li, Miao Cui, and Joseph A. Bonanno . Invest. Ophthalmol. Vis Sci. 2008, 49: 1048-1055.

Dependence of cAMP meditated increases in Cl(-) and HCO(3)(-) permeability on CFTR in bovine corneal endothelial cells. Jinhua Li, KT Allen, X Sun, and JA Bonanno. Exp Eye Res. 2008 Apr; 86(4):684-90

Heather Bradshaw

McHugh D, Walker JM, Bradshaw HB. N-Arachidonoyl glycine potently induces BV-2 cell migration. BJP (submitted Aug 2008)

Hu S S-J, Bradshaw HB , S-C C J, Huang SM, Minassi A, Bisogno T, Masuda K, Roskosk R, Cravatt BF, Di Marzo V, and Walker JM. The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine. FEBS Letters 2008 (submitted July 2008; under revision)

Bradshaw HB, Rimmerman N, Hu S S-J, Masuda K, Cravatt BF, O'Dell DK, Walker JM. Anandamide (N -arachidonoyl ethanolamine) is a precursor for the signaling lipid, N -arachidonoyl glycine through two distinct pathways. (submitted March 2008; under revision )

Huang SM, Lee H, Chung M-K, Yu YY, Bradshaw HB, Coulombe PA, Walker JM, Caterina MJ. Skin keratinocyte TRPV3 ion channels modulate pain sensitivity via prostaglandin E2. J Neuroscience 2008 ( submitted Jan 2008, revised resubmitted Sept 2008)

Bradshaw HB, Rimmerman N, Hu S S-J, Burstien S, and Walker JM. Novel endogenous N-acyl glycines: Identification and Characterization. Vitamins and Hormones (Vol 81) 2008 in press

Rimmerman N, Bradshaw HB, Basnet A., Tan B. Widlanski, TS. Walker JM. Microsomal omega-hydroxylated metabolites of N-arachidonoyl dopamine are active at recombinant human TRPV1 receptors. Prostaglandins and Other Lipid Mediators 2008 (in press; ePub Aug 08).

Rimmerman N, Bradshaw HB, Hughes HV, Chen JS-C, Hu SS-J, McHugh D, Vefring E, Jahnsen JA, Thompson EL, Masuda K, Cravatt BF, Burstein S, Vasko MR, Prieto AL, Walker JM. N -palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharm 2008 Jul;74(1):213-24 ( e-pub April 18 ).

Hu S S-J, Bradshaw HB, Chen J S-C, Tan B, Walker JM. Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol that produces hyperalgesia and modulates NF kappa B activity Br J Pharmacol. 2008 Apr;153(7):1538-49.

Rimmerman N, Hughes HV, Bradshaw HB, Pazos MX, Mackie K, Prieto AL, Walker JM. Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. Br J Pharmacol. 2007 Oct 29

Rubio M, McHugh D, Fernández-Ruiz J, Bradshaw H, Walker JM. Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol. Neurosci Lett. 2007 Jun 29;421(3):270-4. Epub 2007 Jun 2

Burstein SH, Adams JK, Bradshaw HB, Fraioli C, Rossetti RG, Salmonsen RA, Shaw JW, Walker JM, Zipkin RE, Zurier RB. Potential anti-inflammatory actions of the elmiric (lipoamino) acids. Bioorg Med Chem. 2007 May 15;15(10):3345-55. Epub 2007 Mar 13.

Yves Brun

Wagner , J.K. and Y.V. Brun. 2007. Out on a limb: how the Caulobacter stalk can boost the study of bacterial cell shape . Molecular Microbiology, 64: 28-33.

Pierce , D. and Y.V. Brun. 2007. Developmental control in Caulobacter: strategies for survival in oligotrophic environments. In Multicellularity and Differentiation Among the Myxobacteria and Their Neighbors. H. B. Kaplan & D. Whitworth, editors, ASM Press, p. 385-395. Invited review.

Kim, S., A. Bhan, B. Kumar Maryada, K. Choi, and Y.V. Brun. 2007. EGGS: Extraction of Gene clusters using Genome context based Sequence matching techniques. Proceedings of 2007 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2007) November 2-5, 2007, San Jose , CA , USA , IEEE Press.

Li, Z., M. Trimble, Y.V. Brun, and G. Jensen. 2007. The structure of FtsZ filaments in vivo suggests a force-generating role in cell division. The EMBO Journal, 26, 4694-4708. Selected as a “Must read” article by Faculty of 1000. Selected as an article “of outstanding interest” by Current Opinion in Cell Biology.

Lawler, M.L., and Y.V. Brun. 2007. Advantages and mechanisms of polarity and cell shape determination in Caulobacter crescentus. Current Opinions in Microbiology, 10: 630-637. Invited review.

Toh, E, H. D. Kurtz, Jr., and Y.V. Brun. 2008. Characterization of the Caulobacter crescentus Holdfast Polysaccharide Biosynthesis Pathway Reveals Significant Redundancy in the Initiating Glycosyltransferase and Polymerase steps. Journal of Bacteriology, 190, in press.

Bonner, P., G. Hardy, M. Trimble, and Y. V. Brun. Complex regulatory pathways mediate cell cycle progression in Caulobacter crescentus. Advances in Microbial Physiology Volume 52, Elsevier Press, R.K. Poole, editor. Invited review, in press.

Brian Calvi

White, A.E., Leslie, M.E., Calvi, B.R ., Marzluff, W.F., and Duronio,R.J. (2007) Cyclin E/CDK2 regulation of the Drosophila melanogaster histone locus body. Molecular Biology of the Cell 18(7), 2491-2502.

Clark et al. (2007). Evolution of genes and genomes on the Drosophila phylogeny. Nature, 450:203-218 .

Calvi, BR, Byrnes, BA, and Kolpakas, AJ. (2007) Conservation of epigenetic regulation, ORC binding, and developmental timing of DNA replication origins in the genus Drosophila Genetics 177:1291-1301.

Mehrotra, S., Maqbool, S.B., Kolpakas, A., Murnen, K, and Calvi, B.R. 2008 Endocycling Cells do not Apoptose in Response to DNA Re-replication Genotoxic Stress Genes and Development in press.

Lingling Chen

Yali Li, Xinfeng Gao, Lingling Chen. GroEL Recognizes an Amphipathic Helix and Binds to the Hydrophobic Side. Journal of Biological Chemistry. 284(7) 4324-4331, 2009.

Zhida Zheng, Guozhou Chen, Evan D. Brutinel, Timothy L. Yahr, and Lingling Chen.
Biochemical characterization of a regulatory cascade controlling transcription of the
Pseudomonas aeruginosa type III secretion system. J. Biol. Chem. 282:6136-6142,
2007.

Banga, S., Gao, P., Shen, X., Fiscus, V., Zong, W., Chen, L., and Luo, Z. Legionella
pneumophila inhibits macrophage apoptosis by targeting pro-death members of the
Bcl2 protein family. Proc. Natl. Acad. Sci. USA 104:5121-5126, 2007.

Guozhou Chen, Phillip Jeffery, Clay Fuqua, Yigong Shi and Lingling Chen. Structural basis
of TraM anti-activation of quorum sensing transcription factor TraR. Proc. Natl. Acad.
Sci. USA , 104:16474-16479, 2007.

David Clemmer

Merenbloom, S.I., Glaskin, R.S., Clemmer, D.E. High resolution Ion Mobility Spectrometry in a cyclic drift tube (submitted)

Valentine, S.J., Stokes, S.T. Kurulugama, R ., Nachtigall, F.M., Clemmer, D.E. Overtone Mobility Spectrometry (Part 2): Theoretical Considerations of Resolving Power (submitted)

Kurulugama, R., Nachtigall, F.M., Lee, S., Valentine, S.J., Clemmer, D.E. Overtone Mobility Spectrometry (Part1): Experimental Observations (submitted)

Liu, X., Miller, B.R., Rebec, G.V., Naylor, S., Clemmer, D.E. Assessment of Differential Plasma Proteomics in Huntington's Disease (submitted)

Trimpin, S. , Tan, B., Bohrer, B.C., O'Dell, D.K., Merenbloom, S.I., Pazos, M.X., Clemmer, D.E., Walker, J.M. Profiling of Phospholipids and Related Lipid Structures using Multidimensional Ion Mobility Spectrometry-Mass Spectrometry (submitted)

Xun, Z.; Kaufman, T. C.; Clemmer, D. E. Proteome response to the panneural expression of human wild-Type alpha-Synuclein: a Drosophila Model of Parkinson's Disease. J. Proteome Res . (in press)

Trimpin, Sarah; Clemmer, David E. Ion Mobility Spectrometry/Mass Spectrometry Snapshots for Assessing the Molecular Compositions of Complex Polymeric Systems (submitted)

Plasencia, M. D. ; Isailovic, D. ; Merenbloom, S. I. ; Mechref, Y. ; Clemmer, D. E. Resolving and Assigning N-linked Glycan Structural Isomers from Ovalbumin by IMS-MS. J. Am. Soc. Mass Spectrom. (accepted)

Kurulugama, R. T. ; Valentine, S. J.; Sowell, R. A .; Clemmer, D. E. Development of a high-throughput IMS-IMS-MS approach for analyzing mixtures of biomolecules. J. Proteomics (in press)

Xun, Z.; Sowell, R. A .; Kaufman, T. C.; Clemmer, D. E. Quantitative Proteomics of a Presymptomatic A53T alpha-Synuclein Drosophila Model of Parkinson Disease. Mol. Cell. Proteomics, 2008 , 7, 1191-1203.

Alves, P.; Arnold, R. J.; Clemmer, D. E.; Li, Y.; Reilly, J. P.; Sheng, Q.; Tang, H.; Xun, Z .; Zeng, R. ; Radivojac, P. Fast and accurate identification of semi-tryptic peptides in shotgun proteomics. Bioinformatics 2008 , 24(1), 102-109.

Merenbloom, S. I.; Koeniger, S. L.; Bohrer, B. C.; Valentine, S. J. ; Clemmer, D. E. Improving the Efficiency of IMS-IMS by a Combing Technique. Anal. Chem. 2008, 80(6), 1918-1927.

Polfer, N. C.; Bohrer, B. C .; Plasencia, M. D. ; Paizs, B.; Clemmer, D. E. On the dynamics of primary structure scrambling in collision-induced dissociation of peptides J. Phys Chem. A 2008 , 112 , 1286-1293.

Isailovic, D. ; Kurulugama, R. T. ; Plasencia, M. D . ; Stokes, S. T. ; Kyselova, Z. ; Goldman, R. ; Mechref, Y. ; Novotny, M. V. ; Clemmer, D. E. Profiling of Human Serum Glycans Associated with Liver Cancer and Cirrhosis by IMS-MS . J. Proteome Res . 2008 , 7(3), 1109-1117.

Bohrer, B. C.; Merenbloom, S. I.; Koeniger, S. L.; Hilderbrand, A. E.; Clemmer, D. E. Biomolecule Analysis by Ion Mobility Spectrometry , Annu. Rev. Anal. Chem. 2008, 1, 10. 1-10. 35

Trimpin, S.; Clemmer, D. E.; McEwen, C. N. Charge-remote fragmentation of lithiated fatty acids on a TOF-TOF instrument J. Am. Soc. Mass. Spectrom. 2007, 18, 1967-1972.

Sowell, R. A., Hersberger, K. E., Kaufman, T. C., Clemmer, D. E. Examining the Proteome of Drosophila across Organism Lifespan J. Proteome Res. 2007, 6, 3637-3647.

Xun, Z. ; Sowell, R. A. ; Kaufman, T. C.; Clemmer, D. E. Lifetime Proteomic Profiling of an A30P a-synuclein Drosophila Model of Parkinson's Disease J. Proteome Res. 2007, 6, 3729-3738.

Liu, X. ; Miller, B. R.; Rebec, G. V.; Clemmer, D. E. Protein Expression in the Striatum and Cortex Regions of the Brain for a Mouse Model of Huntington's Disease J. Proteome Res. 2007, 6, 3134-3142.

Liu, X.; Valentine, S. J.; Plasencia, M. D .; Trimpin, S.; Naylor, S.; Clemmer, D. E. Mapping the Human Plasma Proteome by SCX-LC-IMS-MS. J. Am. Soc. Mass Spectrom. 2007, 18, 1249-1264. (cover image )

Trimpin, S.; Plasencia, M.; Isailovic, D.; Clemmer, D. E. Resolving Oligomers from Fully Grown Polymers with IMS-MS Anal. Chem. 2007 , 79 , 7965-7974.

Xun, Z.; Sowell, R. A.; Kaufman, T. C.; Clemmer, D. E. Protein Expression in a Drosophila Model of Parkinson's Disease, J. Proteome Research 2007 , 6 , 348-357.

Merenbloom, S. I.; Bohrer, B. C.; Koeniger, S. L .; Clemmer, D. E. Assessing the Peak Capacity of IMS-IMS Separations of Tryptic Peptide Ions in 300 K He . Anal. Chem. 2007, 79, 515-522. ( cover image )

Koeniger, S. L.; Clemmer, D. E. Resolution and Structural Transitions of Elongated States of Ubiquitin. J. Am. Soc. Mass Spectrom. 2007, 18, 322-331.

David Daleke

David L. Daleke, “Phospholipid Flippases”, Journal of Biological Chemistry 282 (2007) 821-825 (invited review).

Smriti and David L. Daleke, “ATP-dependent Transport of Phosphatidylserine Analogs in Human Erythrocytes,” Biochemistry, 46 (2007) 2249-2259.

David L. Daleke, “Regulation of Phospholipid Asymmetry in the Erythrocyte Membrane,” Current Opinion in Hematology 15 (2008) 191-195.

Charles Dann III

Dann, C.E. III, Wakeman, C.A., Seiling, C.L., Baker, S. C. Irnov, I., and WInkler, W. C. Structure and Mechanism of a Metal-Sensing Regulatory RNA. Cell 130:5, 878-92. 2007. [Citations: 11]

Wakeman, C.A., Winkler, W.C., and Dann, C.E. III. Structural Features of Metabolite-Sensing Riboswitches. Trends Biochem Sci 32:9, 415-24, 2007.

Pranav Danthi

Hansberger, M.W., J.A. Campbell, P. Danthi, P. Arrate, K.N. Pennington, K.B. Marcu, D.W. Ballard and T.S. Dermody (2007). I?B Kinase Subunits a and ? Are Required for Activation of NF-?B and Induction of Apoptosis by Mammalian Reovirus. Journal of Virology 81:1360-1371.

Kobayashi T., A. A. R. Antar, K. W. Beohme, P. Danthi, E. A. Eby, K. M. Gugleilmi, G. H. Holm, E. M. Johnson, M. S. Maginnis, S. Naik, W. B. Skelton, J. D. Wetzel, G. J. Wilson, J. D. Chappell, and T. S. Dermody (2007). Plasmid-based reverse genetics for animal double-stranded RNA viruses allows direct manipulation of the viral genome and development of a novel gene-transduction system. Cell Host and Microbe. 1: 147-157.

Holm, G. H., J. Zurney, V. Tumilasci, P. Danthi, J. Hiscott, B. Sherry, and T. S. Dermody (2007). RIG-I and IPS-1 augment proapoptotic responses following mammalian reovirus infrection via IRF-3. Journal of Biological Chemistry. 282: 21953-21961.

Danthi, P., T. Kobayashi, G. H. Holm, M. W. Hansberger, T. W. Abel, and T.S. Dermody. Reovirus apoptosis and virulence are regulated by host cell membrance-penetration efficiency. Submitted.

Richard DiMarchi

2007

DiMarchi, Richard D.; Smiley, David L. Glucagon analogs exhibiting physiological solubility and stability for treating hypoglycemia and weight gain. PCT Int. Appl.(2007), 65pp.

Kohn, W.D., Micanovic, R., Myers, S.L., Vick, A.M., Kahl, S., Zhang, L., Strifler, B., Li, S., Shang, S., Beals, J., Mayer, J.P. and DiMarchi, R.D. pI-shifted Basal Insulin Analogs With Extended in vivo Time Action and Favorable Receptor Selectivity. Peptides (2007) 28 935-948.

Li, Pengyun; Rogers, Tanya; Smiley, David; Di Marchi, Richard D.; Zhang, Faming. Design, synthesis and crystallization of a novel glucagon analog as a therapeutic
agent. Acta Crystallographica, Section F: Structural Biology and Crystallization Communications (2007), F63(7), 599-601.

Ma, Baoquan; Kang, Wei; Yan, Junkai; Gelfanov, Vasily M.; Smiley, David L.; DiMarchi, Richard D. Elaboration of human insulin superagonism through site- selective replacement at TyrB26. Zhongguo Shengwu Gongcheng Zazhi (2007), 27(7), 40-44.

Mayer, John P.; Zhang, Faming; DiMarchi, Richard D. Insulin structure and function. Biopolymers (2007), 88(5), 687-713.

Yan, Liang Zeng; Hsiung, Hansen M.; Heiman, Mark L.; Gadski, Robert A.; Emmerson, Paul J.; Hertel, JeAnne; Flora, David; Edwards, Patrick; Smiley, Dave; Zhang, Lianshan; Husain, Saba; Kahl, Steven D.; DiMarchi, Richard D.; Mayer, John P. Structure- activity relationships of b -MSH derived melanocortin-4 receptor peptide agonists. Current Topics in Medicinal Chemistry (Sharjah, United Arab Emirates) (2007), 7(11), 1052-1067.

Rubén Nogueiras, Paul Pfluger, Sulay Tovar, Arnold Myrtha, Sharon Mitchell, Amanda Morris, Diego Perez-Tilve, Maria J. Vázquez, Petra Wiedmer, Tamara R. Castañeda, Richard DiMarchi, Matthias Tschöp, Annette Schurmann, Hans-Georg Joost, Lynda M. Williams, Wolfgang Langhans, and Carlos Dieguez Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology (2007) 148(1) 21-26.

2008

Cantel, Sonia; Le Chevalier Isaad, Alexandra; Scrima, Mario; Levy, Jay J.; DiMarchi, Richard D.; Rovero, Paolo; Halperin, Jose A.; D'Ursi, Anna Maria; Papini, Anna Maria; Chorev, Michael. Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3- dipolar cycloaddition. Journal of Organic Chemistry (2008), 73(15), 5663-5674.

De, Arnab; DiMarchi, Richard D. Investigation of the Feasibility of an Amide-based Prodrug Under Physiological Conditions. International Journal of Peptide Research and Therapeutics (2008), 14(3), 255-262.

Day, Jonathan; Patterson, James; Chabenne, Joseph; DiMarchi, Maria; Smiley, David; Dimarchi, Richard D.. Preparation of modified glucagons as therapeutic
glucagon/GLP-1 receptor co-agonists with improved solubility and stability. PCT
Int. Appl. (2008),

DiMarchi, Richard D.; DiMarchi, Maria; Chabenne, Joseph. C-terminal substitution
analogs of glucagon with improved solubility at physiological pH. PCT Int. Appl. (2008), 56pp.

Li, Pengyun; Rogers, Tanya; Smiley, David; DiMarchi, Richard D.; Zhang, Faming. Crystallization and preliminary X-ray analysis of anti-obesity peptide hormone
oxyntomodulin. Protein & Peptide Letters (2008), 15(2), 232-234.

Perez-Tilve, D., Hofmann, S.M., Nogueiras, R., Pfluger, P.T., Patterson, J.T., Grant, E., Wilson, H., Granholm, N., Arnold, M., Trevasksi, J.L., Davidson, W.S., DiMarchi, R.D., Woods, S.C., Butler, A.A., Sleeman, M.W., Hui D.Y., and Tschőp, M.H. A gut-brain circuit controls high density lipoprotein cholesterol. PNAS (2008) accepted

Sheffer, Joseph; Norman, Thea; Dimarchi, Richard D.; Putnam, Anna-Maria A. Hays; Feng, Tian; Chu, Stephanie; Krawitz, Denise; Cho, Ho Sung. Modified human plasma polypeptide or Fc scaffolds as carriers for modulating half-life and/or immunogenicity of therapeutic molecules in circulation or serum. PCT Int. Appl. (2008), 240pp.

Bogdan Dragnea

“Self-assembly approaches to nanomaterial encapsulation in viral protein cages”, S. Aniagyei, C. C. DuFort, C. Cheng Kao, B. Dragnea, J. Mater. Chem., 2008, 18, 3763-3774.

“Unnatural life”, B. Dragnea, Nature Mat. 2008; 7: 102-104.

“Self-assembled Virus-like Particles with Magnetic Cores”, Huang, X.; Bronstein, L. M.; Retrum, J.; Dufort, C.; Tsvetkova, I.; Aniagyei, S.; Stein, B.; Stucky, G.; McKenna, B.; Remmes, N.; Baxter, D.; Kao, C. C.; Dragnea, B., Nano Lett. 2007; 7, 2407-2416.

“Reactivity-Based Fluoride Detection: Evolving Design Principles for Spring-Loaded Turn-On Fluorescent Probes” Jiang, X.; Vieweger, M. C.; Bollinger, J. C.; Dragnea, B.; Lee, D.
Org. Lett. 2007; 9, 3579-3582 .

“Structure and Properties of Iron Oxide Nanoparticles Encapsulated by Phospholipids with Poly(ethylene glycol) Tails”, Shtykova, E. V.; Huang, X.; Remmes, N.; Baxter, D.; Stein, B.; Dragnea, B.; Svergun, D. I.; Bronstein, L. M., J. Phys. Chem. C. 2007; 111(49); 18078-18086.

“Core-like Particles of an Enveloped Animal Virus Can Self-Assemble Efficiently on Artificial Templates” Goicochea, N. L.; De, M.; Rotello, V. M.; Mukhopadhyay, S.; Dragnea, B. Nano Lett. 2007; 7, 2281-2290 .

Influence of Iron Oleate Complex Structure on Iron Oxide Nanoparticle Formation
Bronstein, L. M.; Huang, X.; Retrum, J.; Schmucker, A.; Pink, M.; Stein, B. D.; Dragnea, B., Chem. Mater. 2007; 19 (15); 3624-3632.

“Optical field enhancement at cusps between adjacent nanoapertures”, T.D. Onuta, M. Waegele, W. L. Schaich, and B. Dragnea, Nano Lett. 2007, 7, 557-564.

“Core-controlled Polymorphism in Virus-like Particles”, J. Sun, C. DuFort, M.-C. Daniel, A. Murali, C. Chen, K. Gopinath, B. Stein, M. De, V. M. Rotello, A. Holzenburg, C.., Kao, B. Dragnea, Proc. Nat. Acad. Sci, 2007, 104: 1354-1359 .

Jim Drummond

Maillet, D.S. and Drummond, J.T. (2007) J. Mol. Biol., 374(2), 399-410. Constraining Protein Sequence Space: Four Amino Acid Alphabets Are Sufficient to Recapitulate Lambda Repressor Multimerization.

John Foley

Widelitz, RB Veltmaat J, Mayer J Foley, J and Chuong C-M (2007) Mammary glands and feathers: Comparing two skin appendages which help define novel classes during vertebrate evolution. Seminars in Cell and Developmental Biology. 18: 255-266

Foley J, Diamond AG, Gonterman RM, Offutt CD Cho YM. (2007) PTHrP function in the skin: probing beneath the surface. Book Chapter: Novel aspects of PTHrP physiopathology. 41-71.

Lorch G, Gilmore JL, Koltz PF, Gonterman RM, Laughner R , Lewis DA, Konger RL, Nadella KS, Ramiro RE, Rosol TJ, Foley J. (2007) Inhibition of epidermal growth factor receptor signaling reduces hypercalcemia induced by human lung squamous cell carcinoma in athymic mice. British Journal of Cancer 97:183-193.

Gilmore JL, Scott JA , Bouizar Z, Robling A, Pitfield SE, Riese DJ, and Foley J. (2008) Amphireguin-EGFR signaling regulates PTHrP gene expression in breast cancer cells. Breast Cancer Research and Treatment 110: 493-505.

Mayer J, Foley, J, Chuong, C-M and Widelitz, RB (2008) Conversion of the Nipple to Hair Bearing Epithelia by Lowering BMP Pathway Activity at the Dermal-Epidermal Interface. Accepted, American Journal of Pathology.

Patricia Foster

Stumpf, J.D., A.R. Poteete, and P.L. Foster. 2007. Amplification of lac cannot account for adaptive mutation to Lac + in Escherichia coli. J. Bacteriol. 189:2291-2299.

Foster, P.L. 2007. “Measuring Microbial Mutation Rates” In C.A. Reddy (Ed) Methods for General and Molecular Microbiology, 3ed Ed.. ASM Press. (Invited)

Foster, P.L. 2007. Stress-Induced Mutagenesis in Bacteria. Critical Reviews in Biochemistry and Molecular Biology. 42:373-397. (Invited)

Williams, A.B., and P.L. Foster. 2007. The Escherichia coli histone-like protein HU has a role in stationary phase adaptive mutation. Genetics 177: 723-735.

Clay Fuqua

Adebusoye, S., F. W. Picardal, M.O. Ilori, O.O. Amund, C. Fuqua and N. Grindle . Growth on dichlorobiphenyls with chlorine substitution on each ring by bacteria isolated from contaminated African soils. 2007. Appl Microbiol Biotechnol. 74(2):484-92

Adebusoye, S., F. W. Picardal, M.O. Ilori, O.O. Amund, C. Fuqua and N. Grindle . Aerobic degradation of di- and trichlorobenzenes by two bacteria isolated from polluted tropical soils. 2007. Chemosphere 66:1939-1946.

Eberl, L. S. von Bodman and C. Fuqua. 2007. Biofilms on plant surfaces. In S. Kjelleberg and M. Givskov (eds) The Biofilm Mode of Life: Mechanisms and Adaptation, Horizon Bioscience, p. 215-233.

Danhorn, T. and C. Fuqua. 2007. Biofilm formation by plant-associated bacteria. Annu. Rev. Microbiol. 61:401-422.

Klyachko, O., B.D. Stein, N. Grindle, K. Clay and C. Fuqua. 2007. Localization and visualization of a Coxiella -type symbiont within the lone star tick Amblyomma americanum. Appl. Environ. Microbiol. 73:6584-6594.

Chen, G., P.D. Jeffrey, C. Fuqua, Y. Shi, and L. Chen. 2007. Structural basis for anti-activation in bacterial quorum sensing. Proc. Natl. Acad. Sci, USA 104(42):16474-16479 (Track II)

Merritt, P.M., T. Danhorn and C. Fuqua. 2007. Motility and chemotaxis in Agrobacterium tumefaciens surface attachment and biofilm formation. J. Bacteriol. 189:8005-8014.

Adebusoye, S., F. W. Picardal, M.O. Ilori, O.O. Amund and C. Fuqua. 2008. Characterization of multiple novel aerobic polychlorinated biphenyl (PCB)-utilizing bacteria indigenous to contaminated African soils. Biodegradation 119:145-159.

Mohamed, N. ‡., E.M. Cicirelli ‡, J. Kan , F. Chen, C. Fuqua and R.T. Hill. 2008. Diversity and quorum sensing signal production of Proteobacteria associated with marine sponges. Environ. Microbiol. 10:75-86 ‡ (Co-first authors, contributed equally to this study).

Fuqua, C. 2008. Agrobacterium-host attachment and biofilm formation. In T. Tzfira and V. Citovsky (eds) Agrobacterium, From Biology to Biotechnology. Springer Science+Business Media, New York, NY. p. 243-277.

Steiner, F.E., R.R. Pinger, C.N. Vann, N. Grindle, K. Clay, and C. Fuqua. 2008. Infection rates of Anaplasma phagocytophilum variants, Babesia spp, Borrelia burgdorferi and the Ixodes scapularis endosymbiont in Ixodes scapularis from Indiana, Maine, Pennsylvania and Wisconsin. J. Med. Entomol. 45:289-297.

Cicirelli, E.M. , H. Williamson, K.M. Tait and C. Fuqua. 2008. Acylated homoserine lactone signaling in marine bacterial systems. In eds. S.C. Winans and B.L. Bassler, Chemical Communication Among Bacteria , ASM Press, Washington, D.C., p. 251-272.

Clay, K. O. Klyachko, N. Grindle, D. Civitello, D. Oleske and C. Fuqua. 2008. Microbial community ecology of ticks: Prokaryotic diversity, distribution and interactions in the lone star tick, Amblyomma americanum. Mol. Ecol., Early On-Line.

David Giedroc

Liu, T., Ramesh, A., Ma, Z , Ward, S. K., Zhang, L., George, G. N., Talaat, A. M., Sacchettini, J. C., & GIEDROC, D. P. (2007) CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator. Nature Chem. Biol. 3, 60-68.

Liu, P., Li, L., Millership, J. J., Leibowitz, J. L., & GIEDROC, D. P. (2007) A U-turn motif-containing stem-loop in the coronavirus 5' untranslated region (UTR) plays a functional role in replication. RNA 13, 763-780.

Arunkumar, A. I., Pennella, M. A., Kong, X., and GIEDROC, D. P. (2007) Resonance assignments of the metal sensor CzrA in the apo-, Zn2- and DNA-bound (42 kDa) states. Biomol. NMR Assign 1, 99-101.

GIEDROC, D. P. and Arunkumar, A. I. (2007) Metal Sensor Proteins: Nature's metalloregulated allosteric switches. Dalton Trans., 3107-3120 (invited Perspective).

Liu, T., Reyes, H., Li, C., Li, C., Scott, R. A., & GIEDROC, D. P. (2007) Multiple metal-binding domains enhance the Zn(II) selectivity of the divalent metal ion transporter AztA. Biochemistry 46, 11057-11068.

Li, L., Kang, H., Liu, P., Makkinje, N., Williamson, S. T., Leibowitz, J. L., and GIEDROC, D. P. (2008) Structural lability in stem-loop 1 drives a 5' UTR-3' UTR interaction in coronavirus replication. J. Mol. Biol. 377, 790-803.

Chen, X., Hua, H., Balamurugan, K., Kong, X., Wang, L., George, G. N., Georgiev, O., Schaffner, W. and GIEDROC, D. P. (2008) Copper sensing by Drosophila metal-responsive transcription factor-1 requires a Cu(I) 4 -S 6 cluster. Nucl. Acids Res. 36, 3128-3138.

GIEDROC, D. P. and Cornish, P. V. (2008) Frameshifting RNA pseudoknots: structure and mechanism. Vir. Res. 137, in press (invited review).

Tang, X., Thomas, S., Tapia, L., GIEDROC, D. P., & Amato, N. M. (2008) Simulating RNA folding kinetics on approximated energy landscapes. J. Mol. Biol., in press .

Liu, T., Chen, X., Ma, Z., Shokes, J., Hemmingsen, L., Scott, R. A., & GIEDROC, D. P. (2008) A Cu(I)-sensing ArsR-family Metal Sensor Protein with a Relaxed Metal Selectivity Profile. Biochemistry, in press.

Richard Hardy

M. A. Thal*, B. R. Wasik*, J. Posto, and R. W. Hardy. 2007. Template requirements for recognition and copying by Sindbis virus RNA-dependent RNA polymerase. Virology. 358: 221-232. * - equal contribution by these authors.

D. M. Held, J. D. Kissel , S. J. Thacker, D. Michalowski, D. Saran, J. Ji, R. W. Hardy, J. J. Rossi, and D. H. Burke. 2007. Cross-clade inhibition of recombinant HIV-1, HIV-2 and SIVcpz reverse transcriptases by RNA pseudoknot aptamers varies with RNA structure. J. Virol. 81: 5375-5384

J. D. Kissel, D. M. Held, D. Michalowski, R. W. Hardy, and D. H. Burke. 2007. Single-stranded DNA aptamer RT1t49 inhibits RT polymerase and RNase H functions of HIV-1, HIV-2 and SIVCPZ RTs. AIDS Res Hum Retroviruses. 23: 699-708

A. J. Burnham, L. Gong, and R. W. Hardy. 2007. Heterogeneous nuclear ribonuclear protein K interacts with Sindbis virus nonstructural proteins and viral subgenomic mRNA. Virology. 367: 212-221

J. D. Kissel, D. M. Held, R. W. Hardy, and D. H. Burke. 2007. Active site binding and sequence requirements for inhibition of HIV-1 reverse transcriptase by the RT1 family of single-stranded DNA aptamers. Nucleic Acids Research. 35 (15): 5039-5050

J. Rubach*, B. R. Wasik*, J. C. Rupp , R. W. Hardy, and J. Smith. 2008. Characterization of purified full-length alphavirus RNA-dependent RNA polymerase. In revision for Virology. * - equal contribution by these authors.

C. Cheng Kao

Yi, G. and C. Kao. 2007. Selective repression of translation by the Brome Mosaic Virus 1a RNA replication protein. J. Virol. 81: 1601-1609.

Sun, J., DuFort, C. A., Murali, M. D. Daniel, C. Chen, K. Gopinath, B. Stein, M. De, Vince Rotello, A. Holzenburg, C. C. Kao, and B. Dragnea. 2007. Core-controlled polymorphism in virus-like particles. Proc. Natl. Acad. Sci. USA 104:1354-1359.

Zhu, J., K. Gopinath, G. Yi, D. Hayward , H, Zhu, and C. Kao. 2007. RNA-binding Proteins that Inhibit RNA Virus Infection. Proc. Natl. Acad. Sci. USA 104: 3129-9134.

Ranjith-Kumar, C.T., W. Miller, J. Santos, L. Cleveland, M. Park, K. E. Duffy, R. Lamb, R. T. Sarisky, L. Mbow, and C. C. Kao. 2007. Structure-function analyses of the ectodomain of the human TLR3. J. Biol. Chem. 282, 7668-7678.

Ranjith-Kumar, C. T., J. Sun, R. J. Lamb, J. Xiong, J. Santos, K. E. Duffy, W. Miller, A. Holzenburg, R. T. Sarisky, M.L. Mbow and C. Kao. 2007. Effects of single nucleotide polymorphisms in Toll-like Receptor 3 can affect its activity and expression in cultured cells. J. Biol. Chem. 282, 17696-17705.

Gopinath, K., and C. Kao. 2007. Reconstitution of viral RNA infection through trafficking of viral RNAs in plants. The Plant Cell 19, 1-13.

Kang, H. K. Bhardwaj, S. Palaninathan, L. Yi, J. Sacchettini, L. Guarino, J. Leibowitz, and C. Kao. 2007. Biological and biochemical examination of the Mouse Hepatitis Virus Nsp15 endoribonuclease. J. Virol. 81, 13587-13597.

Huang, X., L.M. Bronstein, J. Retrum, C. Dufort, I. Tsvetkova, S. Aniagyei, B. Stein, G. Stucky, B. McKenna, N. Remmes, D. Baxter, C. C. Kao, B. Dragnea. 2007. Self-assembled virus-like particles with magnetic cores. Nano Lett. 7, 2407-2416.

Yi, G., and C. Kao. 2007. Replication and transcription of Brome Mosaic Virus. In “Viral Genome Replication. Eds: M. Götte, K, Raney and C. Cameron. Springer Press.

Bhardwaj, K., S. Palaninathan, L., J. Ortiz, Yi. L. Guarino, J. Sacchettini, and C. Kao. 2008. Structure, function, and substrate specificity for the SARS-CoV Nsp15 endoribonuclease. J. Biol. Chem. 283, 3655-3664.

Yi, G. and C. Kao. 2008. Cis- and trans-acting functions of brome mosaic virus protein 1a in genomic RNA1 replication. J. Virol. 82, 3045-3053.

Gangloff, M., A. Murali, J. Xiong, C. J. Arnot, A.N. Weber, A. M. Sandercock, C.V. Robinson, R. T. Sarisky, A. Holzenburg, C. Kao*. N. J. Gay* (Co-corresponding authors). 2008. An indirect alosteric mechanism for activation of the Toll receptor by the dimeric ligand Spatzle. J. Biol. Chem. 283, 14629-14635.

Ranjith-Kumar, C.T. K.E. Duffy, J.L. Jordan, A. Eaton-Bassiri, R.T. Sarisky, and C. Kao. 2008. Single-stranded deoxyoligonucleotides are potent inhibitors of cytokine production induced by the human Toll-Like Receptor 3. Mol. Cell. Biol. 28: 4507-4519.

Murali, A., X. Li, C.T. Ranjith-Kumar, K. Bhardwaj, A. Holzenburg, P. Li, and C. Kao. 2008. Structure and function of LGP2, a DExD/H helicase that regulates the innate immunity response. J. Biol. Chem. 283:15825-15833.

Chinnaswamy S., I. Yarbrough, S. Palaninathan, C. T. Ranjith Kumar, V. Vijayaraghavan, B. Demeler, S.M. Lemon3, J. C. Sacchettini, and C. C. Kao. 2008. A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase. J. Biol. Chem. 283(29):20535-20546. Cited in Chimera for modeling: http://www.cgl.ucsf.edu/chimera/ImageGallery/

Aniagyei, S.E., DuFort C., Kao, C., and Dragnea, B. Self-assembly approaches to nanomaterial encapsulation in viral protein cages. J. Mater. Chem. DOI 10.1-39/b805874c. In press.

Chen, C., Kao, C. and Dragnea, B. Self-assembly of icosahedral viral capsids: insights from shorter time-scale experiments. J. Phys. Chem. In press.

Ranjith-Kumar, C.T., A. Murali, W. Dong, D. Srisathiyanarayanan, R. Vaughan, J. Ortiz-Alacantara, K. Bhardwaj, X. Li., P. Li, and C. C. Kao. Agonists and antagonists recognition by RIG-I, a cytoplasmic innate immunity receptor. J.B.C. submitted.

Yi, G. H., E. Letteney, C.H. Kim, and C. C. Kao. Brome Mosaic Virus Capsid Protein Regulates Translation of Viral Replication Proteins by Binding to the Replicase Assembly RNA Element. RNA. Submitted.

David Kehoe

Alvey, R. M., Bezy, R. P., Frankenberg-Dinkle, N., and D. M. Kehoe. 2007. A light regulated OmpR-class promoter element coordinates light harvesting protein and chromophore biosynthetic enzyme gene expression. Molecular Microbiology, 64: 319-332.

Li, L., Alvey, R. M., Bezy, R. P., and D. M. Kehoe. 2008. Inverse transcriptional activities during complementary chromatic adaptation are controlled by binding of the response regulator RcaC to red and green light responsive promoters . Molecular Microbiology, 68: 286-297.

Li, L. and D. M. Kehoe. 2008. Abundance changes of the response regulator RcaC require specific aspartate and histidine residues and are necessary for normal light color responsiveness. Journal of Bacteriology, in press.

Ken Mackie

Harkany T, Mackie, K, Doherty, P. Wiring and firing neuronal networks: endocannabinoids take center stage. Curr Opin Neurobiol. 2008 Sep15. [Epub ahead of print]

Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, Galve-Roperh I, Harkany T. Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A. 2008. 105:8760-5.

Suárez J, Bermúdez-Silva FJ, Mackie K, Ledent C, Zimmer A, Cravatt BF, de Fonseca FR. Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei. J Comp Neurol. 2008. 509(4):400-21.

Moussaieff A, Rimmerman N, Bregman T, Straiker A, Felder CC, Shoham S, Kashman Y, Huang SM, Lee H, Shohami E, Mackie K, Caterina MJ, Walker JM, Fride E, Mechoulam R. Incensole acetate, an incense component, elicits psychoactivity by activating TRPV3 channels in the brain. FASEB J. 2008 22:3024-34.

Duncan M, Mouihate A, Mackie K, Keenan CM, Buckley NE, Davison JS, Patel KD Phd, Pittman QJ, Sharkey KA. Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats. Am J Physiol Gastrointest Liver Physiol. 2008 295:G78-G87.

Mackie K. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol. 2008 May;20 Suppl 1:10-4.

Cinar R, Freund TF, Katona I, Mackie K, Szucs M. Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes. Neurochem Int. 2008 52:1402-9.

Daigle TL, Kwok ML, Mackie K. Regulation of CB(1) cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism. J Neurochem. 2008. 106:70-82.

Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K. GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2699-704.

Nyilas R, Dudok B, Urbán GM, Mackie K, Watanabe M, Cravatt BF, Freund TF, Katona I. Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. J Neurosci. 2008 Jan 30;28(5):1058-63.

Cachope R, Mackie K, Triller A, O'Brien J, Pereda AE. Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron. 2007 Dec 20;56(6):1034-47.

Malone DT, Kearn CS, Chongue L, Mackie K, Taylor DA. Effect of social isolation on CB(1) and D(2) receptor and fatty acid amide hydrolase expression in rats. Neuroscience. 2008. 152:265-72.

Rajesh M, Mukhopadhyay P, Haskó G, Huffman JW, Mackie K, Pacher P. CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration. Br J Pharmacol. 2008 Jan;153(2):347-57.

Rimmerman N, Hughes HV, Bradshaw HB, Pazos MX, Mackie K, Prieto AL, Walker JM. Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. Br J Pharmacol. 2008 Jan;153(2):380-9.

Mackie K. Understanding cannabinoid psychoactivity with mouse genetic models. PLoS Biol. 2007 Oct;5(10):e280.

Mackie K. From active ingredients to the discovery of the targets: the cannabinoid receptors. Chem Biodivers. 2007 Aug;4(8):1693-706.

Daigle TL, Kearn CS, Mackie K. Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 2008 Jan;54(1):36-44.

Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Huffman JW, Csiszar A, Ungvari Z, Mackie K, Chatterjee S, Pacher P. CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.

Mátyás F, Urbán GM, Watanabe M, Mackie K, Zimmer A, Freund TF, Katona I. Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. Neuropharmacology. 2008 Jan;54(1):95-107.

Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Mol Pharmacol. 2007 Sep;72(3):612-21.

Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci. 2007 Jul;10(7):870-9.

Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, Mackie K, Harkany T. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science. 2007 May 25;316(5828):1212-6.

Castelli MP, Piras AP, Melis T, Succu S, Sanna F, Melis MR, Collu S, Grazia Ennas M, Diaz G, Mackie K, Argiolas A. Cannabinoid CB1 receptors in the paraventricular nucleus and central control of penile erection: immunocytochemistry, autoradiography and behavioral studies. Neuroscience. 2007 Jun 15;147(1):197-206.

Mátyás F, Watanabe M, Mackie K, Katona I, Freund TF. Molecular architecture of the cannabinoid signaling system in the core of the nucleus accumbens. Ideggyogy Sz. 2007 Mar 30;60(3-4):187-91.

Tappe-Theodor A, Agarwal N, Katona I, Rubino T, Martini L, Swiercz J, Mackie K, Monyer H, Parolaro D, Whistler J, Kuner T, Kuner R. A molecular basis of analgesic tolerance to cannabinoids. J Neurosci. 2007 Apr 11;27(15):4165-77.

Mitrirattanakul S, López-Valdés HE, Liang J, Matsuka Y, Mackie K, Faull KF, Spigelman I. Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence. Alcohol Clin Exp Res. 2007 May;31(5):855-67

Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends Pharmacol Sci. 2007 Feb;28(2):83-92.

Duarte JM, Nogueira C, Mackie K, Oliveira CR, Cunha RA, Köfalvi A. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Exp Neurol. 2007 Mar;204(1):479-84.

Deshmukh S, Onozuka K, Bender KJ, Bender VA, Lutz B, Mackie K, Feldman DE. Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex. Neuroscience. 2007 Mar 2;145(1):279-87.

Chen K, Neu A, Howard AL, Földy C, Echegoyen J, Hilgenberg L, Smith M, Mackie K, Soltesz I. Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. J Neurosci. 2007 Jan 3;27(1):46-58.

Fu J, Astarita G, Gaetani S, Kim J, Cravatt BF, Mackie K, Piomelli D. Food intake regulates oleoylethanolamide formation and degradation in the proximal small intestine. J Biol Chem. 2007 Jan 12;282(2):1518-28.

Oropeza VC, Mackie K, Van Bockstaele EJ. Cannabinoid receptors are localized to noradrenergic axon terminals in the rat frontal cortex. Brain Res. 2007 Jan 5;1127(1):36-44.

Straiker A, Mackie K. Metabotropic suppression of excitation in murine autaptic hippocampal neurons. J Physiol. 2007 Feb 1;578(Pt 3):773-85.

Tuli Mukhopadhyay

Goicochea, N. L, De, M., Rotello, V. M., Mukhopadhyay, S., and Dragnea, B. (2007) Core-like Particles of an Enveloped Animal Virus can Self-Assemble Efficiently on Artificial Templates. NanoLetters.
7(8):2281-90.

David Nelson

McClarty G, Caldwell HD and DE Nelson. 2007. Chlamydial interferon gamma immune evasion influences infection tropism. Current Opinion in Microbiology. 10:1-5.

Nelson DE, Taylor LD, Shannon, JG, Whitmire WM, Crane DD, McClarty G, Su H, Kari L and HD Caldwell. 2007 . Phenotypic rescue of Chlamydia trachomatis growth in IFN-g treated mouse cells by irradiated C. muridarum . Cellular Microbiology. 9 : 2289-98 .

Kari L, Whitmire WM, Carlson JH, Crane DD, Reveneau N, Nelson DE, Mabey DC, Bailey RL, Holland MJ, McClarty G and HD Caldwell. 2008. Pathogenic diversity among Chlamydia trachomatis ocular strains in non human primates is affected by subtle genomic variations. Epub January 16 th . Journal of Infectious Disease.

Ghosh AS, Chowdhury C and DE Nelson. 2008. Physiological implications of D-alanine carboxypeptidases in Escherichia coli. Trends Microbiol. 2008 Jul; 16 (7): 309-17 .

Milos Novotny

Chemical identification of MHC-influenced volatile compounds in mouse urine. I: Quantitative proportions of major chemosignals. M. V. Novotny, H.A. Soini, S. Koyama and K.E. Bruce, Dustin Penn , J. Chem. Ecology 33, 417-434 (2007).

An Automated Method for Peak Detection and Matching in Large Gas Chromatography-Mass Spectrometry Data Sets. S. J. Dixon, R.G. Brereton, H.A. Soini, M.V. Novotny, D.J. Penn, J. Chemometrics. 20, 325-340 (2007).

Porous Polyacrylamide Monoliths in Hydrophilic Interaction Capillary Electrochromatography of Oligosaccharides, V. Guryca, Y. Mechref, A.K. Palm, J. Michálek, V. Pacáková, M.V. Novotny, J. Biochem. Biophys Methods, 70, 3-13 (2007).

High-sensitivity profiling of glycoproteins from human blood serum through multiple-lectin affinity chromatography and liquid chromatography/tandem mass spectrometry, M. Madera, Y. Mechref, I. Klouckova , M.V. Novotny, J. Chromatogr. B. 845, 121-137 (2007).

Individual and Gender Fingerprints in Human Body Odour. D.J. Penn, E. Oberzaucher, K. Grammer, G. Fischer, H.A. Soini, D. Wiesler, M.V. Novotny, S.J. Dixon, Y. Xu, and R.G. Brereton, J. Royal Soc./Interface 4, 331-340 (2007).

Pattern Recognition of Gas Chromatography Mass Spectrometry of Human Volatiles in Sweat to Distinguish the Sex of Subjects and Determine Potential Discriminatory Marker Peaks . S.J. Dixon, Y. Xu, R.G. Brereton, H.A. Soini, M.V. Novotny, E. Oberzaucher, K. Grammer, D.J. Penn, Chemometrics and Intelligent Laboratory Systems, 87, 161-172 (2007).

Seasonal Variation in Volatile Compound Profiles of Preen Gland Secretions of the Dark-Eyed Junco ( Junco hyemalis ). H.A. Soini, S.E. Schrock , K.E. Bruce, D. Wiesler, E.D. Ketterson and M.V. Novotny, J. Chem. Ecology 33, 183-198 (2007).

Comparison of the Methods for Profiling Glycoprotein Glycans: HUPO HGPI (Human Proteome Organization Human Disease Glycomics/Proteome Initiative) Multi-institutional Study.Y. Wada, P. Azadi, C.E. Costello, A. Dell, R.A. Dwek, H. Geyer, R. Geyer, K. Kakehi, N.G. Karlsson, K. Kato, N. Kawasaki, K. Khoo, S. Kim, A. Kondo, E. Lattova, Y.Mechref, E.Miyoshi, K. Nakamura, H. Narimatsu, M.V. Novotny, N.H. Packer, H. Perreault, J. Peter-Katalinic, G. Pohlentz, V.N. Reinhold, P.M. Rudd, A. Suzuki & N. Taniguchi1, Glycobiology 17, 411-422 (2007).

Comparative Glycomic Mapping through Quantitative Permethylation and Stable-Isotope Labeling. P. Kang, Y. Mechref, Z. Kyselova, J.A. Goetz and M.V. Novotny, Anal. Chem., 79, 6064-6073 (2007).

Improved Collision-Induced Dissociation Analysis of Peptides by Matrix-Assisted Laser Desorption/Ionization Tandem Time-of-Flight Mass Spectrometry through 3-Sulfobenzoic Acid Succinimidyl Ester Labeling. William R. Alley , Yehia Mechref, Iveta Klouckova, Milos V. Novotny, J. Proteome Res. 6, 124-132 (2007).

Alterations in the Serum Glycome Due to Metastatic Prostate Cancer. Z. Kyselova, Y. Mechref, M. Al Bataineh, L. E. Dobrolecki, R.J. Hickey, C.J. Sweeney, M.V. Novotny, J. Proteome Res. 6, 1822-1832 (2007).

Synthesis and Characterization of Covalent Mimics of Phosphatidylinositol-4,5-bisphosphate Micelles. Sarah A. Webb, Nichole K. Stewart, Lewis J. Belcher, Yehia Mechref, John W. Tomaszewski, Milos V. Novotny and Martha G. Oakley, Biomacromolecules, 8, 1790-1793 (2007).

Laser-Induced Photofragmentation of Neutral and Acidic Glycans inside an Ion-Trap Mass Spectrometer, Arugadoss Devakumar, Yehia Mechref, Pilsoo Kang , Milos V. Novotny, James P. Reilly, Rapid Commun. Mass Spectrom. 21, 1452-1460 (2007).

Mice Respond Differently to Urine and Its Major Volatile Constituents from Male and Female Ferrets, J-X Zhang, L. Sun, M. Novotny, J. Chem. Ecol. 33, 603-612 (2007).

Application of Dissimilarity Indices, Principal Coordinates Analysis, and Rank Tests to Peak Tables in Metabolomics of the Gas Chromatography/Mass Spectrometry of Human Sweat. Yun Xu, Fan Gong, Sarah J Dixon, Richard G Brereton, H.A. Soini, M.V. Novotny, E. Oberzaucher, K. Grammer, D.J. Penn, . Anal. Chem. 79, 5633-5641 (2007).

A novel function of VCP (valosin-containing protein; P97) in the control of N-glycosylation of proteins in the endoplasmic reticulum. A. Lass, E. McConnell, D. Nowis, Y. Mechref, P. Kang, M.V. Novotny, C. Wojcik, Arch. Biochem. Biophys., 462, 62-73 (2007).

Electrophoretic Analysis of N-Glycans on Microfluidic Devices , Zhuang, Z ., Starkey, J.A., Mechref, Y., Novotny, M.V., and Jacobson , S.C. , Anal. Chem. 79, 7170-7175 (2007).

Advancement in Protein Inference from Shotgun Proteomics Using Peptide Detectability. P. Alves , R. J. Arnold, M. V. Novotny, J. P. Reilly, P. Radivojac, and H. Tang. Pacific Symposium on Biocomputing 12, 409-420 (2007).

Identification of markers for nipple epidermis: changes in expression during pregnancy and lactation. J. Eastwood, C. Offutt, K. Menon, M. Keel, P. Hrncirova, M.V. Novotny, R. Arnold, J. Foley. Differentiation 75, 75-83 (2007).

Comparison of Human Axillary Odour Profiles Obtained by Gas Chromatography Mass Spectrometry and Skin Microbial Profiles Obtained by Denaturing Gradient Gel Electrophoresis Using Multivariate Pattern Recognition, Y. Xu, S.J. Dixon , R.G. Brereton, H.A. Soini, M.V. Novotny, K. Trebesius, I. Bergmaier, E. Oberzaucher, K. Grammer, D.J. Penn, Metabolomics, 3, 427-437 (2007).

A Computational Approach for the Identification of Site-Specific Protein Glycosylations Through Ion-Trap Mass Spectrometry. Y. Wu, Y. Mechref, I. Klouckova , M. V. Novotny, H. Tang. Lecture Notes in Computer Science . 4532, 97-108 (2007).

High-throughput solid-phase permethylation of glycans prior to mass spectrometry. P. Kang , Y. Mechref, M. V. Novotny. Rapid Commun. Mass Spectrom. 22, 721-734 (2008).

Quantitative Chiral Analysis of Salsolinol in Different Brain Regions of Rats Genetically Predisposed to Alcoholism. T Rojkovicova, Y Mechref, J.A. Starkey , M. Al Bataineh, R.L. Bell, W.J. McBride, M. V. Novotny. J. Chromatogr. B, 863, 206-214 (2008).

Social Housing Influences the Composition of Volatile Compounds in the Preputial Glands of Male Rats. L.A. Pohorecky, G.G. Blakley, E.W. Ma, H.A. Soini , D. Wiesler, K.E. Bruce and M.V. Novotny. Hormones and Behavior 53, 4 536-545 (2008).

Profiling of Human Serum Glycans Associated with Liver Cancer and Cirrhosis by IMS-MS. Isailovic D , Kurulugama RT , Plasencia MD , Stokes ST , Kyselova Z , Goldman R , Mechref Y , Novotny MV , Clemmer DE . Journal of Proteome Research 7, 3, 1109-1117 (2008).

Analysis of MALDI-TOF Mass Spectrometry Data for Detection of Glycan Biomarkers. HW Ressom, RS Varghese, L. Goldman, CA Loffredo, M Abdel-Hamid, Z Kyselova, Y Mechref, M Novotny, R Goldman. Pac. Symp. Biocomput. 216-227 (2008).

Analysis of MALDI-TOF Mass Spectrometry Data for Discovery of Peptide and Glycan Biomarkers of Hepatocellular Carcinoma. Ressom, Habtom W.; Varghese, Rency S.; Goldman, Lenka; An, Yanming; Loffredo, Christopher A.; Abdel-Hamid, Mohamed; Kyselova, Zuzana; Mechref, Yehia; Novotny, Milos; Drake, Steven K.; Goldman, Radoslav. Journal of Proteome Research 7, 2, 603-610, (2008).

Breast Cancer Diagnosis/Prognosis through Quantitative Measurements of Serum Glycan Profiles. Z. Kyselova, Y. Mechref , P. Kang , J.A. Goetz, L.E. Dobrolecki, R.J. Hickey, L.H. Malkas, M.V. Novotny Clin. Chem, 54, 7, 1166-1175, (2008).

Identification of Isomeric N-Glycan Structures by Mass Spectrometry with Laser-Induced Photofragmentation. A. Devakumar, Y. Mechref, P. Kang , M.V. Novotny, J.P. Reilly. J. Am. Soc. Mass Spectrom., 19, 1027-1040, (2008).

Efficacy of Glycoprotein Enrichment by Microscale Lectin Affinity Chromatography , Milan Madera, Benjamin Mann , Yehia Mechref, Milos V. Novotny J. Sep. Sci., 31, 2722-2732 (2008).

Glycomic Profiling of Invasive and Non-invasive Breast Cancer Cells, John A. Goetz, Yehia Mechref, Pilsoo Kang , Meei-Huey Jeng, and Milos V. Novotny, Glycoconjugate J., online DOI 10.1007/s10719-008-9170-4 (2008)

Joe Pomerening

Pomerening J. R. Uncovering mechanisms of bistability in biological systems. Curr Opin Biotechnol. 2008 Aug; 19 (4): 381-8.

Tsai T. Y., Choi Y.S., Ma W., Pomerening J.R., Tang C., Ferrell J.E. Jr. Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science. 2008 Jul 4; 321 (5885): 126-9.

Pomerening J.R., Ubersax J.A., Ferrell J.E. Jr. Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF. Mol Biol Cell. 2008 Aug; 19 (8): 3426-41 .

Hansen D.V., Pomerening J.R., Summers M.K., Miller J.J., Ferrell J.E. Jr, Jackson P.K. Emi2 at the crossroads: where CSF meets MPF. Cell Cycle. 2007 Mar 15; 6 (6): 732-8.

Gong D., Pomerening J.R., Myers J.W., Gustavsson C., Jones J.T., Hahn A.T., Meyer T., Ferrell J.E. Jr. Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin B1. Curr Biol. 2007 Jan 9; 17 (1): 85-91 .

Anne Prieto

Prieto, A.L., O’Dell, S., Varnum, B., Lai, C (2007). Localization and signaling of the receptor protein tyrosine kinase Tyro-3 in cortical and hippocampal neurons. Neuroscience. 150 (2): 319-334.

Rimmerman, N., Hughes, H.V., Bradshaw, H.,Pazos, M.X., Mackie, K., Prieto, A.L., Walker, J.M.. (2008) Compartimentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line. Brit. J of Pharma. 153 :380-389.

Tang, A., Jackson, D., Hobbs, J, Chen, W, Smith, J., Patel, H, Prieto, A.L., Petrusca, D., Grivich, M.I, Sher, A., Litke, A., Beggs, J.M. , J.M. (2008) A maximum entropy model applied to spatial and temporal correlations from cortical networks in vitro. J Neurosci.28 (2): 505-518.

Rimmerman, N., Bradshaw, HB., Hughes, V., Chen, J, Shu-Jung Hu, S, J., McHugh, D., Vefring, E., Jahnsen, JA, Thompson, EL., Masuda, K., Cravatt, BF., Burstein, S., Vasko, M. O’Dell, D., Prieto, A.L., Walker, J.M. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium efflux and nitric oxide production in sensory neurons. In press Mol. Pharm. 74(1):213-224.

Binder, M., Cate, H.S., Prieto, A.L., Kemper, D., Butzkueven, H., Gresle, M.M., H, Cipriani, T., Jokubaitis, V., D., Carmeliet, P., Kilpatrick, T.J. (2008) Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone–induced demyelination. J. Neurosci. 28(20):5195-5206.

Jim Reilly

J.A. Karty, W.E. Running , J.P. Reilly, “Two dimensional liquid phase separations of proteins using online fractionation and concentration between chromatographic dimensions”, J. Chromatog. B 847, 103-113 (2007).

M.S. Thompson, W. Cui , J.P. Reilly, “Factors that impact the vacuum ultraviolet photofragmentation of peptide ions”, J. Am. Society for Mass Spectrom., 18, 1439-1452 (2007).

W. Running, S. Ravipaty , J. Karty and J.P. Reilly, “A Top–down/bottom-up study of the ribosomal proteins of Caulobacter crescentus”, J. Proteome Res .6, 337-347 (2007).

A. Devakumar , Y. Mechref, P. Kang , M.V. Novotny, J.P. Reilly, “Laser-Induced photofragmentation of neutral and acidic glycans inside an ion-trap mass spectrometer”, Rapid Commun. Mass Spectrom. 21, 1452-1460 (2007).

X. Liu, W.C. Broshears and .J. P. Reilly, “Probing the structure and activity of trypsin with amidination”, Anal. Biochem., 367, 13-19 (2007).

Yi He and J.P. Reilly, “Does a charge tag really provide a fixed charge?, Angewandte Chemie., 120, 2497-2499 (2008).

A. Devakumar, D.K. O'Dell, J. M. Walker and J.P. Reilly, “Structural analysis of leukotriene C 4 isomers using collisional activation and VUV photodissociation”, J. Am. Soc. Mass Spectrom., 19 14-26 (2008).

R. J. Arnold, William Running and J.P. Reilly, “Analysis of Methylation, Acetylation and other Modifications in Bacterial Ribosomal Proteins” Chap. 11 , pgs, 151-161, Post-translational Modifications of Proteins, Tools for Functional Proteomics, 2 nd Edition , Kannicht, Christoph (Ed.), Methods in Molecular Biology, Vol 446 (2008).

L. Zhang and J.P. Reilly, Use of 157 nm photodissociation to probe structures of y- and b-type ions produced in collision induced dissociation of peptide ions, J. Am. Soc. Mass Spectrom., 19 (5) 695-702 (2008).

A. Devakumar, Y. Mechref, P. Kang, M.V. Novotny and J.P. Reilly Identification of Isomeric N-Glycan Structures by Mass Spectrometry with 157 nm Laser-Induced Photofragmentation, J. Am. Soc. Mass Spectrom. 19, 1027-1040 (2008).

W. Running and J.P. Reilly, Ribosomal Proteins of Deinococcus radiodurans : their Solvent Accessibility and Reactivity, J. Proteome Res. XX, submitted (2008).

J.P. Reilly, Ultraviolet photofragmentation of biomolecular ions, Mass Spectrometry Reviews, in press (2008).

L. Zhang and J.P. Reilly, Extracting both peptide sequence and glycan structural information by 157 nm photodissociation of N-linked glycopeptides, J. Proteome Res. XX , submitted (2008).

Claire Walczak

Ems-McClung, S.C., Hertzer, K.M., Zhang, X., Miller, M., and Walczak, C.E. (2007). The Interplay of the N- and C-terminal Domains of MCAK Control Microtubule Depolymerization Activity and Spindle Assembly. Mol. Biol. Cell. 18: 282-294.

Zhang, X., Lan, W., Ems-McClung, S.C. Stukenberg, P.T., and Walczak, C.E. (2007). Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function. Mol Biol Cell. 18:3264-3276.

Zhang, X., Ems-McClung, S.C., and Walczak, C.E. (2008). Aurora A Phosphorylates MCAK to Control Ran-dependent Spindle Bipolarity. Mol. Biol. Cell. 19: 2752-2765.

Hedrick, D.G., Stout, J.R. and Walczak, C.E. (2008) Effects of anti-microtubule agents on microtubule organization in cells lacking the kinesin-13 MCAK. Cell Cycle. 7: 2146-2156.

Hertzer, K.M, and Walczak, C.E. (2008) The C-termini of Tubulin and the Specific Geometry of Tubulin Substrates Influence the Depolymerization Activity of MCAK. Cell Cycle. 7:2727-2737.

Cai, S. and Walczak, C.E. (in revision). K-Fibres Maintain Chromosome Alignment but are Not Necessary for Chromosome Congression.

Cai, S., Weaver, L., Ems-McClung, S.C., and Walczak, C.E. (submitted). Kinesin-14 Family Proteins HSET/XCTK2 Control Spindle Morphology by Cross-Linking and Sliding Microtubules

Rizk, R., Bohannon, K., Wetzel, L., Powers, J.A., Shaw, S.L, and Walczak, C.E. (submitted). MCAK and Paclitaxel Have Differential Effects on Spindle Organization and Microtubule Dynamics.

Tierno, M.B., Petrick, B., Graham, T.H., Wipf, P., Xu, F., Saunders, W., Kitchens, C., Raccor, F.S., Balachandran, R., Day, B.W., Stout, J.R., Walczak, C.E., Ducruet, A.P., Hindman, C.E., and Lazo, J.S. (in revision). The natural product disorazole C 1 is a potent microtubule disrupting agent that induces premature senescence.

Malcolm Winkler

Lanie, J. A.W.-L. Ng , K. M. Kazmierczak, T. M. Andrzejewski, T. M. Davidsen, K. J. Wayne, H. Tettelin, J. I. Glass, and M. E. Winkler. 2007. Genome Sequence of Avery's Virulent Serotype 2 Strain D39 of Streptococcus pneumoniae and Comparison with That of Unencapsulated Laboratory Strain R6. J. Bacteriol. 189: 38-51.

Ramos-Montañez S., H.-C. T. Tsui, K. J. Wayne , J. L. Morris, L. E. Peters, F. Zhang, K. M. Kazmierczak, L.-T. Sham , and M. E. Winkler. 2008. Polymorphism and Regulation of the spxB (Pyruvate Oxidase) Virulence Factor Gene by a CBS-HotDog Domain Protein (SpxR) in Serotype 2 Streptococcus pneumoniae . 67: 729-746.

Winkler, M. E. and J. A. Hoch. 2008. Essentiality, Bypass, and Targeting of the YycFG (VicRK) Two-Component Regulatory System in Gram-Positive Bacteria, J. Bacteriol. 190 : 2645-2648.

Winkler, M. E. 2008. The Biosynthesis of Histidine. In F.C. Neidhardt, et al. (ed.), Escherichia coli and Salmonella typhimurium : Cellular and Molecular Biology, American Society for Microbiology, Washington, D. C., Edition 3. In press.

Barendt, S. M., A. D. Land, L.-T. Sham, W.-L. Ng , H.-C. T. Tsui, R. J. Arnold, and M. E. Winkler. Capsule Mediates the Cell Shape of pcsB Mutants in Serotype 2 Streptococcus pneumoniae . Submitted to the Journal of Bacteriology.

Adam Zlotnick

Katen, S.P. and Zlotnick, A. (2008) The thermodynamics of virus capsid assembly in Biothermodynamics, Methods in Enz. in press.

Bourne, C.R., Fultz, M.R., and Zlotnick, A. (2008) Participation of assembly-deficient subunits in the self-assembly of an icosahedral virus capsid. Submitted.

Bourne, C. R., Lee, S., Venkataiah, B., Lee, A., Korba, B., Finn, M.G., and Zlotnick, A. (2008) Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight Into Virus Lifecycle. J. Virol. 82, 10262-10270.

Mukherjee, S., Thorsteinsson, M. V., Johnston, L. B., DePhillips, P. A., and Zlotnick, A. (2008) A Quantitative Description of In Vitro Assembly of Human Papillomavirus 16 Virus-like Particles. J. Mol. Biol. 381: 229-37.

Hilmer, J.K., Zlotnick, A., and Bothner, B. (2008) Conformational equilibria and rates of localized motion within Hepatitis B virus capsids. J. Mol. Biol. 375, 581-94

Zlotnick, A., Lee, A., Bourne, C.R., Johnson, J.M., Domanico, P.L., and Stray, S.J. (2007) In vitro screening for molecules that affect virus capsid assembly (and other protein association reactions). Nature Protocols 2, 490-8.  Cover illustration.

Zlotnick, A. (2007) Distinguishing reversible from irreversible virus capsid assembly. J. Mol. Biol. 366, 14-18.