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Look at this, a complete cross section of a pituitary gland! We want to concentrate on the area right at the edge of the gland for the infiltration of the histiocytes. |
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The histiocytic infiltrate in this case is around the capsule of the gland. It is kind of subtle, and you may want to check on the histology of the normal gland to appreciate the difference. The histiocytes do not look particular aggressive, but they continue to slowly reproduce and cause organ failure. |