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This is a high grade malignant astrocytic glial tumor.
You will see areas of necrosis and marked nuclear atypia of the malignant
cells. Pay special attention to the reactive, yet highly atypical looking,
vascular changes in the capillary sized vessels. The endothelial cells
become extremely agitated in the presence of this tumor. You should see
some large pink staining cells at the periphery of this lesion; they are
called gemistocytes, gem like cells. These are benign reactive glial cells,
and similar changes are seen in many types of central nervous system injury.
This tumor is highly aggressive and universally fatal, at least at the
present time. |
