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Clemmer Group Publications

 

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Submitted or In Press

149. Kurulugama, R. T.; Nachtigall, F. M.; Valentine, S. J.; Clemmer, D. E. Overtone Mobility Spectrometry: Part 3. OMS-OMS for Complex Mixture Analysis (submitted).
148. Xun, Z., Kaufman, T.C., Clemmer, D.E. Stable Isotope labeling and label-free proteomics of Drosophila parkin null mutants (submitted).
147. Liu, X., Miller, B.R., Rebec, G.V., Naylor, S., Clemmer, D.E. Assessment of Differential Plasma Proteomics in Huntington’s Disease (submitted)
146. Valentine, S. J.; Clemmer, D. E. Protein oligomers frozen in time. Nature Chemistry (In Press)
145. Valentine, S. J.; Clemmer, D. E. Treatise on the Measurement of Molecular Masses with Ion Mobility Spectrometry Anal. Chem. (In Press)
 

Published

144.

Trimpin, S., Tan, B., Bohrer, B.C., O’Dell, D.K., Merenbloom, S.I., Pazos, M.X., Clemmer, D.E., Walker, J.M. Profiling of Phospholipids and Related Lipid Structures using Multidimensional Ion Mobility Spectrometry-Mass Spectrometry. International Journal of Mass Spectrometry 2009, 287, 58-69.

143. Valentine, S. J.; Kurulugama, R. T.; Bohrer, B. C.; Merenbloom, S. I.; Sowell, R. A.; Mechref, Y; Clemmer, D. E. Developing IMS–IMS–MS for rapid characterization of abundant proteins in human plasma. International Journal of Mass Spectrometry 2009, 283, 149–160.
142. Merenbloom, Samuel I.; Glaskin, Rebecca S.; Henson, Zachary B.; Clemmer, David E. High-Resolution Ion Cyclotron Mobility Spectrometry. Analytical Chemistry 2009, 81(4), 1482-1487.
141. Valentine, S.J., Stokes, S.T. Kurulugama, R., Nachtigall, F.M., Clemmer, D.E. Overtone Mobility Spectrometry (Part2): Theoretical Considerations of Resolving Power. J. Am. Soc. Mass Spectrom. 2009, 20 (5), 738-750.
140. Kurulugama, R., Nachtigall, F.M., Lee, S., Valentine, S.J., Clemmer, D.E. Overtone Mobility Spectrometry (Part1): Experimental Observations J. Am. Soc. Mass Spectrom.  2009,  20 (5), 729-737.
139. Xun, Z.; Kaufman, T. C.; Clemmer, D. E. Proteome response to the panneural expression of human wild-Type -Synuclein: a Drosophila Model of Parkinson’s Disease.  J. Proteome Res. 2008, 7, 3911-3921
138. Trimpin, Sarah; Clemmer, David E. Ion Mobility Spectrometry/Mass Spectrometry Snapshots for Assessing the Molecular Compositions of Complex Polymeric Systems. Analytical Chemistry 2008 80 (23), 9073-9083.
137. Plasencia, M. D. ; Isailovic, D. ; Merenbloom, S. I. ; Mechref, Y. ; Clemmer, D. E. Resolving and Assigning N-linked Glycan Structural Isomers from Ovalbumin by IMS-MS. J. Am. Soc. Mass Spectrom. 2008, 19(11), 1706-1715.
136.

Kurulugama, R. T.; Valentine, S. J.; Sowell, R. A.; Clemmer, D. E. Development of a high-throughput IMS-IMS-MS approach for analyzing mixtures of biomolecules. J. Proteomics, 2008, 71(3), 318-331.

135. Xun, Z.; Sowell, R. A.; Kaufman, T. C.; Clemmer, D. E. Quantitative Proteomics of a Presymptomatic A53T {alpha}-Synuclein Drosophila Model of Parkinson Disease. Mol. Cell. Proteomics, 2008, 7, 1191-1203.
134.

Alves, P. ; Arnold, R. J. ; Clemmer, D. E. ; Li, Y. ; Reilly, J. P. ; Sheng, Q. ; Tang, H. ; Xun, Z. ; Zeng, R. ; Radivojac, P. Fast and accurate identification of semi-tryptic peptides in shotgun proteomics. Bioinformatics 2008, 24(1), 102-109.

133.

Merenbloom, S. I. ; Koeniger, S. L. ; Bohrer, B. C. ; Valentine, S. J. ; Clemmer, D. E. Improving the Efficiency of IMS-IMS by a Combing Technique. Anal. Chem. 2008, 80(6), 1918-1927.

132.

Polfer, N. C.; Bohrer, B. C.; Plasencia, M. D.; Paizs, B.; Clemmer, D. E. On the dynamics of primary structure scrambling in collision-induced dissociation of peptides J. Phys Chem. A 2008, 112, 1286-1293.

131.

Isailovic, D. ; Kurulugama, R. T. ; Plasencia, M. D. ; Stokes, S. T. ; Kyselova, Z. ; Goldman, R. ; Mechref, Y. ; Novotny, M. V. ; Clemmer, D. E. Profiling of Human Serum Glycans Associated with Liver Cancer and Cirrhosis by IMS-MS. J. Proteome Res. 2008, 7(3), 1109-1117.

130.

Bohrer, B. C. ; Merenbloom, S. I. ; Koeniger, S. L. ; Hilderbrand, A. E. ; Clemmer, D. E. Biomolecule Analysis by Ion Mobility Spectrometry, Annu. Rev. Anal. Chem. 2008, 1, 10. 1-10. 35

129.

Trimpin, S.; Clemmer, D. E.; McEwen, C. N. Charge-remote fragmentation of lithiated fatty acids on a TOF-TOF instrument J. Am. Soc. Mass. Spectrom. 2007, 18, 1967-1972.

128.

Sowell, R. A., Hersberger, K. E., Kaufman, T. C., Clemmer, D. E. Examining the Proteome of Drosophila across Organism Lifespan J. Proteome Res. 2007, 6, 3637-3647.

127.

Xun, Z.; Sowell, R. A.; Kaufman, T. C.; Clemmer, D. E. Lifetime Proteomic Profiling of an A30P α-synuclein Drosophila Model of Parkinson's Disease J. Proteome Res. 2007, 6, 3729-3738.

126.

Liu, X.; Miller, B. R.; Rebec, G. V.; Clemmer, D. E. Protein Expression in the Striatum and Cortex Regions of the Brain for a Mouse Model of Huntington's Disease J. Proteome Res. 2007, 6, 3134-3142.

125.

Liu, X.; Valentine, S. J.; Plasencia, M. D.; Trimpin, S.; Naylor, S.; Clemmer, D. E. Mapping the Human Plasma Proteome by SCX-LC-IMS-MS. J. Am. Soc. Mass Spectrom. 2007, 18, 1249-1264. (cover image)

124.

Trimpin, S.; Plasencia, M.; Isailovic, D.; Clemmer, D. E. Resolving Oligomers from Fully Grown Polymers with IMS-MS Anal. Chem. 2007, 79, 7965-7974.

123.

Xun, Z.; Sowell, R. A.; Kaufman, T. C.; Clemmer, D. E. Protein Expression in a Drosophila Model of Parkinson's Disease, J. Proteome Research 2007, 6, 348-357.

122.

Merenbloom, S. I.; Bohrer, B. C.; Koeniger, S. L.; Clemmer, D. E. Assessing the Peak Capacity of IMS-IMS Separations of Tryptic Peptide Ions in 300 K He. Anal. Chem. 2007, 79, 515-522. (cover image)

121.

Koeniger, S. L.; Clemmer, D. E.  Resolution and Structural Transitions of Elongated States of Ubiquitin. J. Am. Soc. Mass Spectrom. 2007, 18, 322-331.

120.

Myung, S.; Lorton, P.; Merenbloom, S. I.; Fioroni, M.; Koeniger, S. L.; Julian, R. R.; Baik, M-H.; Clemmer, D. E. Evidence for Spontaneous Resolution of Icosahedral Proline. J. Am. Chem. Soc. 2006 128, 15988-15989.

119.

Valentine, S. J.; Plasencia, M. D.; Liu, X.; Krishnan, M.; Naylor, S.; Udseth, H. R.; Smith, R. D.; Clemmer, D. E.  Toward Plasma Proteome Profiling with Ion Mobility-Mass Spectrometry, J. Proteome Research  2006, 5, 2977-2984.

118.

Myung, S.; Fioroni, M.; Julian, R. R.; Koeniger, S. L.; Baik, M-H.; Clemmer, D. E. Chirally Directed Formation of Nanometer-Scale Proline Clusters, J. Am. Chem. Soc.  2006, 128, 10833-10839.

117.

Koeniger, S. L.; Merenbloom, S. I.; Sevugarajan, S.; Clemmer, D. E.  Transfer of Structural Elements from Compact to Extended States in Unsolvated Ubiquitin, J. Am. Chem. Soc.  2006, 128, 11713-11719.

116.

Hilderbrand, A. E.; Myung, S.; Clemmer, D. E.  Exploring Crown Ethers as Shift Reagents for Ion Mobility Spectrometry, Anal. Chem.  2006, 78, 6792-6800.

115.

Tang, H.; Arnold, R. J.; Alves, P.; Xun, Z.; Clemmer, D. E.; Novotny, M. V.; Reilly, J. P.; Radivojac, P.  A Computational Approach Toward Label-free Protein Quantification using Predicted Peptide Detectability, Bioinformatics  2006, 22, 481-488.

114.

Valentine, S. J.; Sevugarajan, S.; Kurulugama, R. T.; Koeniger, S. L.; Merenbloom, S. I.; Bohrer, B. C.; Clemmer, D. E.  Split-Field Drift Tube/Mass Spectrometry and Isotopic Labeling Techniques for Determination of Single Amino Acid Polymorphisms, J. Proteome Research  20065, 1879-1887.

113.

Koeniger, S. L.; Merenbloom, S. I.; Valentine, S. J.; Jarrold, M. F.; Udseth, H.; Smith, R.; Clemmer, D. E.  An IMS-IMS Analogue of MS-MS, Anal. Chem.  2006, 78, 4161-4174.
112.

Myung, S.; Valentine, S. J.; Clemmer, D. E. Ion-Mobility Spectrometry Combined with Mass Spectrometry:  Principles and Applications in Protein Characterization in Encyclopedia of Mass Spectrometry (Hyphenated Methods , Volume 8), Gross, M. L.; Caprioli, R. and Niessen, W. M. A., Eds.; Elsevier: Kidlington, Oxford, 2006.

111.

Merenbloom, S. I.; Koeniger, S. L.; Valentine, S. J.; Plasencia, M. D.; Clemmer, D. E. IMS-IMS and IMS-IMS-IMS/MS for Separating Peptide and Protein Fragment Ions, Anal. Chem.  2006, 78, 2802-2809.  

110.

Koeniger, S. L.; Merenbloom, S. I.; Clemmer, D. E. Evidence for Many Resolvable Structures within Conformation Types of Electrosprayed Ubiquitin Ions, J. Phys. Chem B  2006, 110, 7017-7021.

109.

Myung, S.; Wiseman, J. M.; Valentine, S. J.; Zoltán, T. Cooks, R. G.; Clemmer, D. E.  Coupling Desorption Electrospray Ionization (DESI) with Ion Mobility/Mass Spectrometry for Analysis of Protein Structure: Evidence for Desorption of Folded and Denatured States, J. Phys. Chem B  2006, 110, 5045-5051.

108.

Badman, E.; Myung, S.; Clemmer. D. E.  Evidence for Unfolding and Refolding of Gas Phase Cyctrochrome c Ions in a Paul Trap, J. Am. Soc. Mass Spectrom2005, 16, 1493-1497.

107.

Taraszka, J. A.; Gao, X.; Valentine, S. J.; Sowell, R. A.; Koeniger, S. L; Miller, D. F.; Kaufman, T. C.; Clemmer, D. E.  Proteome Profiling for Assessing Diversity: Analysis of Individual Heads of Drosophila melanogaster Using LC-Ion Mobility-MS, J. Proteome Research  2005, 4, 1238-1247.

106.

Taraszka, J. A.; Kurulugama, R.; Sowell, R.; Valentine, S. J.; Koeniger, S. L; Arnold, R. J.; Miller, D. F.; Kaufman, T. C.; Clemmer, D. E.  Mapping the Proteome of Drosophila melanogaster: Analysis of Embryos and Adult Heads by LC-IMS-MS Methods, J. Proteome Research  2005, 4, 1223-1237.

105.

Valentine, S. J.; Liu, X.; Plasencia, M. D.; Hilderbrand, A. E.; Kurulugama, R. T.; Koeniger, S. L.; Clemmer, D. E.  Developing liquid chromatography ion mobility mass spectrometry techniques, Expert Rev. Proteomics  2005, 2, 553-565.

104.

Myung, S.; Pink, M.; Baik, M.; Clemmer, D. E.  DL-Proline, Acta Cryst.  2005, C61, 506-508.

103.

Wong, R. L.; Counterman, A. E.; Clemmer, D. E.; Williams, E. R.  Evaluation of Ion Mobility Spectroscopy for Determining Charge-Solvated versus Salt-Bridge Structures of Protonated Trimers, J. Am. Soc. Mass Spectrom.  2005, 16, 1009-1019.

102.

Hilderbrand, A. E.; Clemmer, D. E.  Determination of Sequence-Specific Intrinsic Size Parameters from Cross Sections for 162 Tripeptides, J. Phys. Chem B  2005, 109, 11802-11809.

101.

Julian, R. R.; Myung, S.; Clemmer, D. E.  Do Homochiral Aggregates Have an Entropic Advantage?  J. Phys. Chem. B  2005, 109, 440-444.

100.

Koeniger, S. L.; Valentine, S. J.; Myung, S.; Plasencia, M.; Lee, Y. L.; Clemmer, D. E.    Development of Field Modulation in a Split-Field Drift Tube for High-Throughput Multi-dimensional Separations, J. Proteome Research  2005, 4, 25-35.

99.

Liu, X.; Plasencia, M.; Ragg, S.; Valentine, S. J.; Clemmer, D. E.  Development of High-Throughput Dispersive LC-Ion Mobility-TOFMS Techniques for Analyzing the Human Plasma Proteome, Brief Funct Genomic Proteomic  2004, 3, 177-186.

98.

Nanita, S. C.; Takats, Z.; Myung, S.; Clemmer, D. E.; Cooks, R. G.  Chiral Enrichment in Serine via Formation, Dissociation and Soft-Landing of Octameric Cluster Ions, J. Am. Soc. Mass Spectrom.  2004, 15, 1360-1365.

97.

Sowell, R. A.; Koeniger, S. L.; Valentine, S. J.; Moon, M. H.; Clemmer, D. E.  Nanoflow LC/IMS-MS (and -CID/MS) of Protein Mixtures, J. Am. Soc. Mass Spectrom.  2004, 15, 1341-1353.

96.

 Myung, S.; Julian, R. R.; Nantia, S. C.; Cooks, R. G.; Clemmer, D. E.  Formation of Nanometer Scale Serine Clusters by Sonic Spray, J. Phys. Chem B  2004, 108, 6105-6111. 

95.

Julian, R. R.; Myung, S.; Clemmer, D. E.  Spontaneous Anti-Resolution in Heterochiral Clusters of Serine, J. Am. Chem. Soc.  2004, 126, 4110-4111.

94.

Counterman, A. E.; Clemmer, D. E.   Anhydrous Polyproline Helices and Globules, J. Phys. Chem. B  2004, 108, 4885-4898.

93.

Srebalus Barnes, C. A.; Clemmer, D. E.  Ion Mobility/Time-of-Flight Analysis of Combinatorial Library Mixtures in High Throughput Analysis: A Tool for Combinatorial Materials Science; Potyrailo, R. A.  and  Amis, E. J., Eds.; Kluwer Academic/Plenum Publishers: New York, NY, 2003, p. 187-216.

92.

Hilderbrand, A. E.; Myung, S.; Srebalus Barnes, C. A.; Clemmer, D. E.  Development of LC-IMS-CID-TOFMS Techniques: Analysis of a 256 Component Tetrapeptide Combinatorial Library, J. Am. Soc. Mass Spectrom.  2003, 14, 1424-1436.

91.

Srebalus Barnes, C. A.; Clemmer, D. E.  Assessing Intrinsic Side Chain Interactions Between i and i+4 Residues in Solvent-Free Peptides:  A Combinatorial Gas-Phase Approach, J. Phys. Chem. A  2003, 107, 10566-10579. {invited for special issue honoring Charlie Parmenter}

90.

Moon, M. H.; Myung, S.; Plasencia, M.; Hilderbrand, A. E.; Clemmer, D. E.  Nanoflow LC/Ion Mobility/CID/TOF for Proteomics: Analysis of a Human Urinary Proteome, J. Proteome Research  2003, 2, 589-597.

89.

Valentine, S. J.; Koeniger, S. L.; Clemmer, D. E.  A Split-field Drift Tube for Separation and Efficient Fragmentation of Biomolecular Ions, Anal. Chem.  2003, 75, 6202-6208.

88.

Myung, S.; Lee, Y. L.; Moon, M. H.; Taraszka, J. A.; Sowell, R.; Koeniger, S. L.;  Hilderbrand A. E.; Valentine, S. J.; Cherbas, L.; Cherbas, P.; Kaufmann, T. C.; Miller, D. F.; Mechref, Y.; Novotny, M. V.; Ewing, M.; Clemmer D. E.  Development of High-Sensitivity Ion Trap-IMS-TOF Techniques:  A High-Throughput Nano-LC/IMS/TOF Separation of the Drosophila Fly Proteome, Anal. Chem.  2003, 75, 5137-5145.

87.

Hilderbrand, A. E.; Valentine, S. J.; Clemmer, D. E.  Mobilities:  Biological Systems and Clusters in Encyclopedia of Mass Spectrometry (Theory and Ion Chemistry, Volume 1); Gross, M. L.; Caprioli, R. and Armentrout, P., Eds.; Elsevier: Kidlington, Oxford, 2003, p. 506-520.

86.

Que, A. H.; Mechref, Y.; Huang, Y.; Taraszka, J. A.; Clemmer, D. E.; Novotny, M. V.  Coupling Capillary Electrochromatogarphy with Fourier-Transform Mass Spectrometry for Characterizing Complex Oligosaccharide Pools, Anal. Chem.  2003, 75, 1684-1690.

85.

Counterman, A. E.; Clemmer, D. E.  Compact -> Extended Helix Transitions of Polyalanine in Vacuo, J.  Phys. Chem. B  2003, 107, 2111-2117.

84.

Counterman, A. E.; Thompson, M. S.; Clemmer, D. E.  Identifying a protein by MALDI-TOF Mass Spectrometry: An Experiment for the Undergraduate Laboratory, J. of Chem. Edu.  2003, 80, 177-180.

83.

Lee, Y. J.; Hoaglund-Hyzer, C. S.; Srebalus Barnes, C. A.; Hilderbrand, A. E.; Valentine, S. J.; Clemmer, D. E.  Development of High-Throughput LC-injected Ion Mobility-Q-TOF Techniques for Analysis of Complex Peptide Mixtures, J. Chromatography B  2002, 782, 343-351. {invited for the special Proteomics issue}

82.

Counterman, A. E.; Clemmer, D. E.  Gas Phase Polyalanine: Assessment of i->i+3 and i->i+4 Helical Turns in [Alan+4H]4+ (n = 29 -49) Ion, J. Phys. Chem. B  2002, 106, 12045-12051.

81.

Myung, S.; Badman, E.; Lee, Y. J.; Clemmer, D. E.  Structural Transitions of Electrosprayed Ubiquitin Ions Stored in an Ion Trap over ~10 ms to 30s, J. Phys. Chem. A  2002, 106, 9976-9982. {A special issue to celebrate Jack Beauchamp's 60th birthday}

80.

Badman, E.; Myung, S.; Clemmer, D. E.  Gas-Phase Separations of Protein and Peptide Ion Fragments Generated by Collision-Induced Dissociation in an Ion Trap, Anal. Chem.  2002, 74, 4889-4894.

79.

Badman, E. R.; Hoaglund-Hyzer, C. S.; Clemmer, D. E.  Dissociation of Different Conformations of Ubiquitin IonsJ. Am. Soc. Mass Spectrom.  2002, 13, 719-723.

78.

Valentine, S. J.; Clemmer, D. E.  Temperature Dependent H/D Exchange of Compact and Elongated Cytochrome c Ions in the Gas Phase, J. Am. Soc. Mass Spectrom.  2002, 13, 506-517.

77.

Counterman, A. E.; Clemmer, D. E.  Cis-Trans Signatures of Proline-Containing Tryptic Peptides in the Gas Phase, Anal. Chem.  2002, 74, 1946-1951.

76.

Leavell, M. D.; Gaucher, S. P.; Leary, J. A.; Taraszka, J. A.; Clemmer, D. E.  Conformational Studies of Zn-Ligand-Hexose Diastereomers Using Ion Mobility Measurements and Density Functional Theory Calculations, J. Am. Soc. Mass Spectrom.  2002, 13, 284-293.

75.

Mosier, P. D.; Counterman, A. E.; Jurs, P. C.; Clemmer, D. E.  Prediction of Peptide Ion Collision Cross Sections from Topological Molecular Structure and Amino Acid Parameters, Anal. Chem.  2002, 74, 1360-1370.

74.

Hoaglund-Hyzer, C. S.; Lee, Y. J.; Counterman, A. E.; Clemmer, D. E.  Coupling Ion Mobility Separations, Collisional Activation Techniques, and Multiple Stages of MS for Analysis of Complex Peptide Mixtures, Anal. Chem.  2002, 74, 992-1006.

73.

Kindy, J. M.; Taraszka, J. A.; Regnier, F. E.; Clemmer, D. E.  Quantifying Peptides in Isotopically Labeled Protease Digests by Ion Mobility/Time-of-Flight Mass Spectrometry, Anal. Chem.  2002, 74, 950-958.

72.

Srebalus Barnes, C. A.; Hilderbrand, A. E.; Valentine, S. J.; Clemmer, D. E.  Resolving Isomeric Peptide Mixtures: A Combined HPLC/Ion Mobility-TOFMS Analysis of a 4000-Component Combinatorial Library, Anal. Chem.  2002, 74, 26-36.

71.

Valentine, S. J.; Kulchania, M.; Srebalus Barnes, C. A.; Clemmer, D. E.  Multidimensional separations of complex peptide mixtures: a combined high-performance liquid chromatography/ion mobility/time-of-flight mass spectrometry approach, Int. J. Mass Spectrom.  2001, 212, 97-109. {A special issue celebrating R. Graham Cooks' 60th birthday}

70.

Badman, E. R.; Hoaglund-Hyzer, C. S.; Clemmer, D. E.  Monitoring Structural Changes of Proteins in an Ion Trap over ~10-200 ms: Unfolding Transitions in Cytochrome c Ions, Anal. Chem.  2001, 73, 6000-6007.

69.

Counterman, A. E.; Clemmer, D. E.  Magic Number Clusters of Serine in the Gas Phase, J. Phys. Chem. B  2001, 105, 8092-8096.

68.

Lee, Y. J.; Hoaglund-Hyzer, C. S.; Taraszka, J. A.; Zientara, G. A.; Counterman, A. E.; Clemmer, D. E.  Collision-Induced Dissociation of Mobility-Separated Ions Using an Orifice-Skimmer Cone at the Back of a Drift Tube, Anal. Chem.  2001, 73, 3549-3555.

67.

Counterman, A. E.; Hilderbrand, A. E.; Srebalus Barnes, C. A.; Clemmer, D. E.  Formation of Peptide Aggregates during ESI: Size, Charge, Composition, and Contributions to Noise, J. Am. Soc. Mass Spectrom.  2001, 12, 1020-1035.

66.

Shvartsburg, A. A.; Siu, K. W. M.; Clemmer, D. E.  Prediction of Peptide Ion Mobilities via a priori Calculations from Intrinsic Size Parameters of Amino Acid Residues, J. Am. Soc. Mass Spectrom.  2001, 12, 885-888.

65.

Johannessen, S. C.; Brisbois, R. G.; Fischer, J. P.; Grieco, P. A.; Counterman, A. E.; Clemmer, D. E.  A Nano-Scale Barrel and Cube: Transition Metal-Mediated Self-Assembly of CpCoCb-Derived Ligand Scaffolds, J. Am. Chem. Soc.  2001, 123, 3818-3819.

64.

Ideue, S.; Sakamoto, K.; Honma, K.; Clemmer, D. E.  Conformational change of electrosprayed cytochrome c studied by laser-induced fluorescence, Chem. Phys. Lett.  2001, 337, 79-84.

63.

Taraszka, J. A.; Counterman, A. E.; Clemmer, D. E.  Gas-Phase separations of complex tryptic peptide mixtures, Fresenius J. Anal. Chem.  2001, 369, 234-245.

62.

Counterman, A. E.; Clemmer, D. E.  Large Anhydrous Polyalanine Ions: Evidence for Extended Helices and Onset of a More Compact State, J. Am. Chem. Soc.  2001, 123, 1490-1498.

61.

Taraszka, J. A.; Counterman, A. E.; Clemmer, D. E.  Large anhydrous polyalanine ions: substitution of Na+ for H+ destabilizes folded states, Int. J. Mass Spectrom.  2001, 204, 87-100.

60.

Srebalus Barnes, C. A.; Clemmer, D. E.  Assessment of Purity and Screening of Peptide Libraries by Nested Ion Mobility-TOFMS: Identification of RNase S-protein Binders, Anal. Chem.  2001, 73, 424-433.

59.

Hoaglund-Hyzer, C. S.; Clemmer, D. E.  Ion Trap/Ion Mobility/Quadrupole/Time-of-Flight Mass Spectrometry for Peptide Mixture Analysis, Anal. Chem.  2001, 73, 177-184.

58.

Hoaglund-Hyzer, C. S.; Li, J.; Clemmer, D. E.  Mobility Labeling for Parallel CID of Ion Mixtures, Anal. Chem.  2000, 72, 2737-2740.

57.

Taraszka, J. A.; Li, J.; Clemmer, D. E.  Metal-Mediated Peptide Ion Conformations in the Gas Phase, J. Phys. Chem. B  2000, 104, 4545-4551.

56.

Srebalus, C. A.; Li, J.; Marshall, W. S.; Clemmer, D. E.  Determining Synthetic Failures in Combinatorial Libraries by Hybrid Gas-Phase Separation Methods, J. Am. Soc. Mass Spectrom.  2000, 11, 352-355.

55.

Valentine, S. J.; Counterman, A. E.; Clemmer, D. E.  A Database of 660 Peptide Ion Cross Sections: Use of Intrinsic Size Parameters for Bona Fide Predictions of Cross Sections, J. Am. Soc. Mass Spectrom.  1999, 10, 1188-1211.

54.

Hoaglund Hyzer, C. S.; Counterman, A. E.; Clemmer, D. E.  Anhydrous Protein Ions, Chem. Rev.  1999, 99, 3037-3079.

53.

Henderson, S. C.; Li, J.; Counterman, A. E.; Clemmer, D. E.  Intrinsic Size Parameters for Val, Ile, Leu, Gln, Thr, Phe, and Trp Residues from Ion Mobility Measurements of Polyamino Acid Ions, J. Phys. Chem. B  1999, 103, 8780-8785.

52.

Srebalus, C. A.; Li, J.; Marshall, W. S.; Clemmer, D. E.  Gas-Phase Separations of Electrosprayed Peptide Libraries, Anal. Chem.  1999, 71, 3918-3927.

51.

Counterman, A. E.; Clemmer, D. E.  Volumes of Individual Amino Acid Residues in Gas-Phase Peptide Ions, J. Am. Chem. Soc.  1999, 121, 4031-4039.

50.

Valentine, S. J.; Counterman, A. E.; Hoaglund-Hyzer, C. S.; Clemmer, D. E.  Intrinsic Amino Acid Size Parameters from a Series of 113 Lysine-Terminated Tryptic Digest Peptide Ions, J. Phys. Chem. B  1999, 103, 1203-1207.

49.

Henderson, S. C.; Valentine, S. J.; Counterman, A. E.; Clemmer, D. E.  ESI/Ion Trap/Ion Mobility/Time-of-Flight Mass Spectrometry for Rapid and Sensitive Analysis of Biomolecular Mixtures, Anal. Chem.  1999, 71, 291-301.

48.

Valentine, S. J.; Counterman, A. E.; Hoaglund, C. S.; Reilly, J. P.; Clemmer, D. E.  Gas-Phase Separations of Protease Digests, J. Am. Soc. Mass Spectrom.  1998, 9, 1213-1216.

47.

Li, J.; Taraszka, J. A.; Counterman, A. E.; Clemmer, D. E.  Influence of solvent composition and capillary temperature on the conformations of electrosprayed ions:  unfolding of compact ubiquitin conformers from pseudonative and denatured solutions, Int. J. Mass. Spectrom.  1999, 185/186/187, 37-47.

46.

Hoaglund, C. S.; Valentine, S. J.; Sporleder, C. R.; Reilly, J. P.; Clemmer, D. E.  Three-Dimensional Ion Mobility/TOFMS Analysis of Electrosprayed Biomolecules, Anal. Chem.  1998, 70, 2236-2242.

45.

Counterman, A. E.; Valentine, S. J.; Srebalus, C. A.; Henderson, S. C.; Hoaglund, C. S.; Clemmer, D. E.  High-Order Structure and Dissociation of Gaseous Peptide Aggregates that are Hidden in Mass Spectra, J. Am. Soc. Mass Spectrom.  1998, 9, 743-759.

44.

Schroder, D.; Schwartz, H.; Clemmer, D. E.; Chen, Y.; Armentrout, P. B.; Baranov, V. I.; Bohme, D. K.  Activation of Hydrogen and Methane by Thermalized FeO+ in the Gas Phase as Studied by Multiple Mass Spectrometric Techniques, Int. J. Mass Spectrom. Ion Proc.  1997, 161, 175-191.

43.

Hoaglund, C. S.; Valentine, S. J.; Clemmer, D. E.  An Ion Trap Interface for ESI-Ion Mobility Experiments, Anal. Chem.  1997, 69, 4156-4161.

42.

Liu, Y.; Valentine, S. J.; Counterman, A. E.; Hoaglund, C. S.; Clemmer, D. E.  Injected-ion Mobility Analysis of Biomolecules, Anal. Chem.  1997, 69, 728A.

41.

Hoaglund, C. S.; Liu, Y.; Ellington, A. D.; Pagel, M.; Clemmer, D. E.  Gas-Phase DNA: Oligothymidine Ion Conformers, J. Am. Chem. Soc.  1997, 119, 9051-9052.

40.

Liu, Y.; Clemmer, D. E.  Characterizing Oligosaccharides Using Injected-Ion Mobility/Mass Spectrometry, Anal. Chem.  1997, 69, 2504-2509.

39.

Clemmer, D. E.; Jarrold, M. F.  Ion Mobility Measurements and their Applications to Clusters and Biomolecules, J. Mass Spectrom.  1997, 32, 577-592.

38.

Valentine, S. J.; Counterman, A. E.; Clemmer, D. E.  Conformer-Dependent Proton-Transfer Reactions of Ubiquitin Ions, J. Am. Soc. Mass Spectrom. 1997, 8, 954-961.

37.

Valentine, S. J.; Anderson, J. G.; Ellington, A. D.; Clemmer, D. E.  Disulfide-Intact and -Reduced Lysozyme in the Gas Phase: Conformations and Pathways of Folding and Unfolding, J. Phys. Chem. B  1997, 101, 3891-3900.

36.

Valentine, S. J.; Clemmer, D. E.  H/D Exchange Levels of Shape-Resolved Cytochrome c Conformers in the Gas Phase, J. Am. Chem. Soc.  1997, 119, 3558-3566.

35.

Dugourd, Ph.; Hudgins, R. R.; Clemmer, D. E.; Jarrold, M. F.  High-resolution ion mobility measurements, Rev. Sci. Instrum.  1997, 68, 1122-1129.

34.

Shelimov, K. B.; Clemmer, D. E.; Hudgins, R. R.; Jarrold, M. F.  Protein Structure in Vacuo: The Gas Phase Conformations of BPTI and Cytochrome c, J. Am. Chem. Soc.  1997, 119, 2240-2248.

33.

Shelimov, K. B.; Clemmer, D. E.; Jarrold, M. F.  Metal Containing Carbon Clusters, J. Chem. Soc. Dalton Trans.  1996, 567-574.

32.

Shelimov, K. B.; Clemmer, D. E.; Hunter, J. M.; Jarrold, M. F.  Ion Mobility Studies of the Structures and Isomerization of Gas Phase Carbon and Metal Containing Carbon Clusters, in The Chemical Physics of Fullerenes 10 (and 5) Years Later; NATO-ASI Series E, (Kluwer, Dordrecht, 1996) p. 71-87.

31.

Clemmer, D. E.; Hudgins, R. R.; Jarrold, M. F.  Naked Protein Conformations: Cytochrome c in the Gas Phase, J. Am. Chem. Soc.  1995, 117, 10141-10142.

30.

Shelimov, K. B.; Clemmer, D. E.; Jarrold, M. F.  Drift Tube Studies of Metallofullerenes, in Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials (Proceedings of The Electrochemical Society Vol. 95-10), R. S. Ruoff and K. M. Kadish, Eds., (The Electrochemical Society, Pennington, NJ, 1995) p. 1437-1447.

29.

Shelimov, K. B.; Clemmer, D. E.; Jarrold, M. F.  Structures and Isomerization of LaCn+ Clusters, J. Phys. Chem.  1995, 99, 11376-11386.

28.

Clemmer, D. E.; Jarrold, M. F.  Metal-Containing Carbon Clusters: Structures, Isomerization, and Formation of NbCn+ Clusters, J. Am. Chem. Soc.  1995, 117, 8841-8850.

27.

Clemmer, D. E.; Hunter, J. M.; Shelimov, K. B.; Jarrold, M. F.  Physical and Chemical Evidence for Metallofullerenes with Metal Atoms as Part of the Cage, Nature  1994, 372, 248-250.

26.

Chen, Y.M.; Clemmer, D. E.; Armentrout, P. B.  Kinetic and Electronic Energy Dependence of the Reactions of Sc+ and Ti+ with D2O, J. Phys. Chem.  1994, 98, 11490-11498.

25.

Shelimov, K. B.; Clemmer, D. E.; Jarrold, M. F.  Structures and Formation of Small LaCn+ Metallofullerenes, J. Phys. Chem.  1994, 98, 12819-12821.

24.

Honma, K.; Nakamura, M.; Clemmer, D. E.; Koyano, I.  Kinetics of Ti (a 3F, a5F) and V(a4F, a6D) Depletion by NH3 and H2S, J. Phys. Chem.  1994, 98, 13286-13293.

23.

Honma, K.; Clemmer, D. E.  The Importance of the Electron Transfer Mechanism in Reactions of Neutral Transition Metal Atoms, Laser Chem.  1994, 15, 209-220.

22.

Chen, Y. M.; Clemmer, D. E.; Armentrout, P. B.  Conversion of CH4 to CH3OH: Reactions of CoO+ with CH4 and D2, Co+ with CH3OD and D2O, and Co+(CH3OD) with Xe, J. Am. Chem. Soc.  1994, 116, 7815-7826.

21.

Clemmer, D. E.; Shelimov, K. B.; Jarrold, M. F.  Bonding of Metals to Carbon Rings: LaCn+ Isomers with La+ Inserted and Attached to the Ring, J. Am. Chem. Soc.  1994, 116, 5971-5972.

20.

Clemmer, D. E.; Chen, Y. M.; Khan, F. A.; Armentrout, P. B.  State-Specific Reactions of Fe+(a6D, a4F) with D2O and Reactions of FeO+ with D2, J. Phys. Chem.  1994, 98, 6522-6529.

19.

Clemmer, D. E.; Chen, Y. M.; Aristov, N.; Armentrout, P. B.  Kinetic and Electronic Energy Dependence of the Reaction V+ with D2O, J. Phys. Chem.  1994, 98, 7538-7544.

18.

Clemmer, D. E.; Jarrold, M. F.  Structural Dynamics of Carbon and Metal Containing Carbon Clusters, in Laser Techniques for State-Selected and State-to-State Chemistry II, SPIE Proc1994, 2124, 400.

17.

Clemmer, D. E.; Shelimov, K. B.; Jarrold, M. F.  Gas-Phase Self-Assembly of Endohedral Metallofullerenes, Nature 1994, 367, 718-720.

16.

Clemmer, D. E.; Honma, K.; Koyano, I.  Kinetics of Excited State Ti(a5F) Depletion by NO, O2, N2O, and N2, J. Phys. Chem.  1993, 97, 11480-11488.

15.

Khan, F. A.; Clemmer, D. E.; Schultz, R. H.; Armentrout, P. B.  Sequential Bond Energies of Cr(CO)x+, x = 1 - 6, J. Phys. Chem.  1993, 97, 7978-7987.

14.

Chen, Y. M.; Clemmer, D. E.; Armentrout, P. B.  Gas-phase thermochemistry of VH and CrH, J. Chem. Phys.  1993, 98, 4929-4936.

13.

Clemmer, D. E.; Aristov, N.; Armentrout, P. B.  Reactions of ScO+, TiO+, and VO+ with D2: M+-OH Bond Energies and Effects of Spin Conservation, J. Phys. Chem.  1993, 97, 544-552.

12.

Clemmer, D. E.; Weber, M. E.; Armentrout, P. B.  Reactions of Al+(1S) with NO2, N2O and CO2: Thermochemistry of AlO and AlO+, J. Phys. Chem.  1992, 96, 10888-10893.

11.

Clemmer, D. E.; Armentrout, P. B.  Direct determination of the adiabatic ionization energy of NO2 as measured by guided ion-beam mass spectrometry, J. Chem. Phys.  1992, 97, 2451-2458.

10.

Armentrout, P. B.; Clemmer, D. E.  Guided Ion Beam Studies of the Energetics of Organometallic Species, in Energetics of Organometallic Species, Simoes, J. A. M., Eds.; Kluwer: Netherlands, 1992; pp. 321-356.

9.

Clemmer, D. E.; Dalleska, N. F.; Armentrout, P. B.  Gas-Phase Thermochemistry of the Group 3 Dioxides: ScO2, YO2 and LaO2, Chem. Phys. Lett.  1992, 190, 259-265.

8.

Clemmer, D. E.; Dalleska, N. F.; Armentrout, P. B.  Reaction of Zn+ with NO2. The gas-phase thermochemistry of ZnO, J. Chem. Phys.  1991, 95, 7263-7268.

7.

Clemmer, D. E.; Elkind, J. L.; Aristov, N.; Armentrout, P. B.  Reaction of Sc+, Ti+, and V+ with CO. MC+ and MO+ bond energies, J. Chem. Phys.  1991, 95, 3387-3393.

6.

Chen, Y.M.; Clemmer, D. E.; Armentrout, P. B.  The gas-phase thermochemistry of TiH, J. Chem. Phys.  1991, 95, 1228-1233.

5.

Clemmer, D. E.; Armentrout, P. B.  Ammonia Activation by Co+, Ni+, and Cu+. M+-NH2 Bond Energies and M+NH3 Adduct Lifetimes, J. Phys. Chem.  1991, 95, 3084-3090.

4.

Fisher, E. R.; Elkind, J. L.; Clemmer, D. E.; Georgiadis, R.; Loh, S. K.; Aristov, N.; Sunderlin, L. S.; Armentrout, P. B.  Reactions of fourth-period metal ions (Ca+ - Zn+) with O2: Metal-oxide ion bond energies, J. Chem. Phys.  1990, 93, 2676-2691.

3.

Clemmer, D. E.; Sunderlin, L. S.; Armentrout, P. B.  Ammonia Activation by Sc+ and Ti+: Electronic and Translational Energy Dependence, J. Phys. Chem.  1990, 94, 3008-3015.

2.

Clemmer, D. E.; Sunderlin, L. S.; Armentrout, P. B.  Ammonia Activation by V+: Electronic and Translational Energy Dependence, J. Phys. Chem.  1990, 94, 208-217.

1.

Clemmer, D. E.; Armentrout, P. B.  Investigation of Isomeric Intermediates: Co+-NH3 and H-Co+-NH2, J. Am. Chem. Soc.  1989, 111, 8280-8281.

        Last modified:   July 14, 2008