Student internships:

If you are a student at IU and are interested in getting some research experience, we routinely have projects of varying duration and complexity. Depending on the project and your degree of engagement, such a project may result in authorship on a publication. Ryan Kellogg (now finishing up medical school at Duke University) worked with us for a year as an undergraduate and published a first-author paper in the Journal of Neurophysiology (Kellogg et al., 2009) while IU undergraduate Megan Hutchenson was included on several articles (Hu et al., 2010, Straiker et al., in press).


Sample projects:

Basic project: Cannabinoid circuitry in the retina and anterior eye - using antibodies developed by Dr. Mackie's laboratory to investigate cannabinoid circuitry of the mammalian eye. Our first effort was published last year (Hu et al., 2010) in the Journal of Comparative Neurology. Learn immunohistochemistry, confocal microscopy and basic ocular anatomy. A project at this level requires a few days of training and can be done with as little as 5 hours a week.

Basic project: Dynamic tracking of cannabinoid-related proteins - using fluorescently tagged cannabinoid-related proteins and the new robotic confocal microscope at the LMIC, track the behavior of proteins in real-time.

Basic project: Cannabinoid regulation of intraocular pressure in mice - we are testing an assortment of agents and genetic mutants to investigate the underpinnings of cannabinoid regulation of intraocular pressure using a mouse model. With two million Americans suffering from glaucoma, this work has considerable implications for human health.

Major project: Electrophysiological investigation of cannabinoid signaling - use advanced single-cell recording techniques to record from individual neurons and determine how cannabinoids modulate their signaling. Ephys involves a long learning curve - candidate would have to show both commitment (at least one year, 15+ hrs. week) and aptitude.