Office Hours:	Monday and Wednesday, 11-12:00
			Tuesday and Thursday, 10-12
			or by appointment

			005 HPER; Phone:   855-7975;   email:
afly@indiana.edu

Course Description:	 lecture, 4 credits, P: Chem C341 and HPER
N231 or consent of instructor. Functions of nutrients in human
metabolism, review of past and current literature.  This course is
cross-listed with N430.
Course Objectives:	
	1.	Students will be able to define and interpret the
processes of digestion, absorption, transport and excretion of
protein, carbohydrate and fat.
	2.	Students will be able to explain the
interrelationships of protein, carbohydrate and fat in supplying
energy and essential dietary substances to the body.
	3.	Students will be able to interpret the regulation of
metabolism.
	4.	Students will be able to describe the basis for the
nutrient requirements.
	5.	Students will be able to describe the utilization of
protein, carbohydrate, and fat, in fed, fasting, and starvation
conditions.
	6.	Students will understand the relationships of fat,
carbohydrate, and protein calories in relationship to development or
exacerbation of chronic disease.
	7.	Students will become familiar with the work of
prominent researchers in the field of nutrition.

Text: 	Groff, J.L., and Gropper, S. S.  1999.  Advanced Nutrition and
Human Metabolism.  West Publishing Co., 3rd edition.

Evaluation:	Exams, 4 @ 100 points each, 50% of course grade.
		Homework - 10 assignments @10 points each, 12.5% of
course grade
		Quizzes  - 4 @ 15 points each, 7.5% of course grade  		

		Participation, 40 points, 5% of course grade, is
measured by attendance.  You will not receive any of these points if
you miss 5 or more classes.  Attendance is taken at the beginning of
class.  You are marked absent if you are late.
		Nutrition Profiles - 50 profiles @ 4 points each, 25%
of course grade - see handout on completing profiles of past and
present nutritionists

Grades:  	Grades will be assigned based on achievement of the
following percentages: 93-100 = A		<80-77 = C+
				<93-90 = A-		<77-72 = C
				<90-87 = B+ 		<72-70 = C-
				<87-82 = B		<70-60 = D
				<82-80 = B-		<60 = F
		  	Academic and personal misconduct by students
in this class are defined and dealt with according to the procedures
in the Code of Student Ethics.


Course Outline:
												
Reading
												
Assignment
August	28 (M)	Intro to the course and Who's 				
1-21
				Who in the cell
	  	30 (W) 	Digestion and Absorption				
24-49

September	  4 (M)	Energy Transformation					
53-69
		  6 (W)	Carbohydrates: Structure, Digestion and
Absorption     70-81
				Homework 1 due

		  11 (M)	Carbohydrates: glycogenesis,
glycogenlysis, 		       81-85
		  13 (W)	Carbohydrates: glycolysis, hexose
monophosphate          85-93
				shunt, Krebs (TCA cycle),
				Homework 2 due
				Quiz 1

		  18 (M)	Carbohydrates: Metabolism  -
gluconeogenesis	      94-95
				15 Profiles Due
		  20 (W)	Exam 1				
														

		  25 (M)	Regulation of Metabolism 				
96-103
		  27 (W)	Carbohydrates: Dietary Fiber				
106-122
				Homework 3 due

October	    2 (M)	Lipids: Fatty acids, nomenclature, properties	
123-129
		    4 (W)	Lipids: Sterols and Steroids				
129-133
				Homework 4 Due

		    9 (M)	Lipids: Digestion, Absorption,
Transport		    133-144
	   	   11 (W)	Lipid Metabolism:   -oxidation, ketone
formation        144-151
				Homework 5 Due
				Quiz 2

	            16 (M)	Cholesterol metabolism						
-
		  18 (W)	Exam 2

	            23 (M)	Lipids: Fatty Acid Synthesis,				
151-154
				15 Profiles Due
		  25 (W)	Regulation of Lipid Metabolism				
155-162
				Homework 6 Due
				
	  30 (M)	Basic Protein Structure 1 -4 ; amino
acid	           163-167
				classification
November	    1 (W)	Digestion and Absorption				
168-177
				Homework 7 Due								

		    6 (M)	Catabolism: Transamination &
Deamination	          178-185
		    8 (W)	Urea cycle							
186-196
				Homework 8 Due
				Quiz 3

		   13 (M)	Organ-specific metabolism				
196-207
		   15 (W)	Exam 3

		  20 (M)	Protein intake and quality				
208-212
				Homework 9 Due
				15 Profiles Due
		  22 (W)	Thanksgiving Recess - No class

November	  27 (M)	Interrelationships of Protein,
Carbohydrate and Fat  216-240
				in fed, fasting and starvation states
				5 Profiles Due
	   	 29 (W)	Endocrine function: Diabetes, Alcohol
Metabolism     242-244
				Homework 10 Due
				Quiz 4
				Course evaluations today!

December	  4 (M)	Body Composition						
501-516
		  6 (W)	Energy Balance and Weight Control			
517-525

		  15(W)	Final Exam - 10:15 a.m.-12:15 p.m.