Course Format: Lecture: 12:20P-1:10P, MWF, JH A106.

Course requirements: L211, M250, and M255.

Course description. Bacterial pathogenesis and antibiotic
chemotherapy will be covered in detail. Emphasis will be placed on
the molecular bases and mechanisms underlying bacterial diseases and
the mechanisms of action of and development of resistance to
antibiotics used to treat these diseases. The course will present
current fundamental concepts in these areas as well as draw on more
traditional medical microbiology sources.

Required texts: “Bacterial Pathogenesis: A Molecular Approach” by
A.A. Salyers and D. D. Whitt and “Antibiotics: Actions, Origins, and
Resistance” by C. Walsh. Additional medical microbiology, immunology,
and antibiotic texts will be on reserve and referred to in class.

Weekly assignments: Reading for lectures. Discussion of material.

Exams/Papers: Four examinations, each covering roughly 25% of the
material in the course. Occasional in-class worksheets and out-of-
class assignments will be given.