Indiana University
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The Gill Center for Biomolecular Science

Kyung-Tai (Tai) Min

Tai MinAssociate Professor, Department of Biology

Office: Jordan Hall 341
TEL: 856-0962
Email: kyumin@indiana.edu

Education

  • Ph.D., University of Oxford, 1993

Research

  • Molecular mechanisms of Down syndrome, neurological disorders, and aging

Representative Publications

  • Griswold, A., Chang, K.T., Runko, A., Knight, M., and Min, K-T. (2008). Sir2 mediates apoptosis through JNK-dependent pathway in Drosophila. Proc. Natl. Acad. Sci. USA. in press.
  • Runko, A., Griswold, A, and Min, K-T. (2008). Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan in Drosophila. FEBS Letters, 582, 715-719.
  • Davies K. J, Ermak G, Rothermel BA, Pritchard M, Heitman J, Ahnn J, Henrique-Silva F, Crawford D, Canaider S, Strippoli P, Carinci P, Min K-T, et al. (2007). Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J. 21, 3023-3-28.
  • Chang, K.T., and Min, K-T. (2005). Drosophila melanogaster homolog of Down Syndrome Critical Region 1 is critical for mitochondrial function. Nature Neuroscience, 8, 1577-1585.
  • Menzies, F., Yenisetti, S., Min, K-T. (2005). Roles of Drosophila DJ-1 in oxidative stress and survival of dopaminergic neurons. Current Biology, 6, 1578-1582.
  • Cho, Y., Griswold, A., Campbell, C., and, Min, K-T. (2005). Individual histone deacetylases in Drosophila modulate transcription of distinct genes. Genomics, 86, 606-617.
  • Taylor, J.P., Taye, A.A., Campbell, C. Kazemi-Esfarjani, P., Fischbeck, K.H., and Min, K-T. (2003). Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein. Genes & Development 17, 1463-1468.
  • Chang, K.T., Shi, Y.J., and Min, K-T. (2003). The Drosophila homolog of human Down’s Syndrome Critical Region 1 gene regulates learning: Implications for mental retardation. Proc. Natl. Acad. Sci. USA 100, 15794-15799.
  • Pramatarova, A, Ochalski, P.W., Chen, K., Gropman, A, Myers, S., Min, K-T., Howell, B.W. (2003). Nck-b interacts with tyrosine phosphorylated disabled 1 and redistributes in reelin-stimulated neurons. Mol. Cell. Biol. 23, 7210-7221.
  • Kang, H., Benzer, S., and Min, K-T.(2002). Life extension in Drosophila by feeding a drug. Proc. Natl. Acad. Sci. USA 99, 838-843.