sen xu
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Sen Xu
senxu (at) indiana (dot) edu
(812) 856-0115

Ph.D., Environmental Science, University of Windsor, Canada, 2011

M.Sc., Evolutionary Biology, University of Amsterdam, The Netherlands, 2005

B.Sc., Biology, Ocean University of China, China, 2003

Research

For my postdoctoral research, I use Daphnia as a model system to explore why sex and recombination evolved. Daphnia typically reproduces via cyclical parthenogenetic reproduction (alternation of sexual and asexual reproduction), thus providing a nice contrast between sexual and asexual reproduction. I plan to use population genomic approach to study the genetic mechanisms and consequences of the transition into asexual reproduction. Furthermore, I am interested in estimating the population genetic parameters such as crossover rate, gene conversion rate, and effective population sizes using diploid whole-genome data.

 


Publications

Xu S, Innes DJ, Lynch M, and Cristescu ME. (2013) The role of hybridization in the origin and spread of asexuality in Daphnia. Molecular Ecology. 22:4549-4561.

Tucker AE, Ackerman MS, Eads BD, Xu S, and Lynch M (2013) Population-genomic insights into the evolutionary origin and fate of obligately asexual Daphnia pulex. Proceedings of the National Academy of Sciences. In press

Ibarra-Laclette et al. (including Xu S) (2013) Architecture and evolution of a minute plant genome. Nature. 498, 94-98.

Altshuler I, Vaillant J, Xu S, Cristescu ME. (2012) The evolutionary history of Sarco(endo)plasmic Calcium ATPase (SERCA). Plos One 7: e52617.

Xu S, Schaack S, Seyfert A, Choi E, Lynch M, and Cristescu ME. (2012) High mutation rates in the mitochondrial genomes of Daphnia pulex. Molecular Biology and Evolution 29:763-769.

Altshuler I, Demiri B, Xu S, Constantin A, Yan ND, Cristescu ME. (2011) An integrated multi-disciplinary approach for studying multiple stressors in freshwater ecosystems: Daphnia as a model organism. Integrative and Comparative Biology 51:623-633.

Millette KJ*, Xu S, Witt JDS, Cristescu ME. (2011) Pleistocene-driven diversification in freshwater zooplankton: Refugial isolation, postglacial re-colonization, and cryptic speciation. Limonology and Oceanography 56: 1725-1736. *supervised undergraduate student

Xu S, Omilian AR, Cristescu ME. (2011) High rate of large-scale hemizygous deletions in asexually propagating Daphnia: implications for the evolution of sex. Molecular Biology and Evolution 28: 335-342.

Huang XN, Shi XL, Xu S, Liu GJ, Ma LM, Sun ZQ. (2011) Life history characteristics of Macrothrix rosea (Jurine, 1820) (Cladocera, Macrothricidae) in laboratory conditions. Journal of Limnology 70: 248-254.

Shi X, Xu S, Xue C, Huang X, Liu, G, Zhao Y. (2011) Discovery of males of Simocephalus himalayensis (Cladocera, Simocephalus), with the re-description of females. Chinese Journal of Oceanology and Limonology 29: 206-212.

Xu S, Hebert PDN, Kotov AA, Cristescu ME. (2009) The noncosmopolitanism paradigm of freshwater zooplankton: insights from the global phylogeography of the predatory cladoceran Polyphemus pediculus (Linnaeus, 1761)
(Crustacea, Onychopoda). Molecular Ecology 18: 5161-5179.

Roessingh P, Xu S, Menken SBJ. (2007) Olfactory receptors on the maxillary palps of small ermine moth larvae: evolutionary history of benzaldehyde sensitivity. Journal of Comparative Physiology A - Neuroethology Sensory Neural and Behavioral Physiology 193: 635-647.