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Indiana University Bloomington

Faculty from several departments participate in our Graduate Program. They are listed according to the following research area.

students in labs

Tuli MukhopadyayTuli Mukhopadhyay

Associate Professor, Biology

Office: Simon Hall 220C

Phone: 812/856-3686

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Lab Website


Ph.D., University of Illinois at Chicago, 1996
Postdoctoral Fellow, University of Texas, Southwestern Medical Center,
Purdue University, 1999-2005


Structure and assembly of enveloped, RNA viruses
Alphavirus Structure and Assembly

Representative Publications

Zeng, X., Mukhopadhyay, S., Brooks III, C. L. (2015) Residue level resolution of alphavirus envelope protein interactions in pH dependent fusion. PNAS. In press.

Mohari, B., Licata, N. A., Kysela, D. T., Merritt, P. M., Mukhopadhyay, S., Brun, Y. V., Setayeshgar, S., and Fuqua, C. (2015) Novel Pseudotaxis Mechanisms Improve Migration of Straight Swimming Bacterial Mutants through a Porous Environment. mBio. In press.

Tsetsarkin, K.A., Chen, R., Yun, R., Rossi, S.L., Plante, K.S., Guerbois, M., Forrester, N., Perng, G.C., Sreekumar, E., Leal, G., Huang, J., Mukhopadhyay, S., and Weaver, S.C. (2014) Multi-peaked Aedes albopictus-adaptive landscape for chikungunya virus evolution predicts continued increases in transmissibility. Nat Commun. 16(5):4084-4097. PMID 24933611

Li, Z., Dilger, J. M., Pejaver, V., Smiley, D., Arnold, R., Mooney, S., Mukhopadhyay, S., Radivojac, P., and Clemmer, D. (2014) Intrinsic Size Parameters for Palmitoylated and Carboxyamidomethylated Peptides. Inter. J. Mass Spec. 368:6-14.

Snyder, A.J., Mukherjee, S., Glass, J. K., Kearns, D. B., and Mukhopadhyay, S. (2014). The canonical twin-arginine translocase components are not required for secretion of folded GFP from B. subtilis. J. Applied and Environmental Microbiology. Appl. Environ. Microbiol., 80(10):3219-3232. PMID 24632256

Sokoloski, K.J., Snyder, A.J., Liu, N.H., Hayes, C.A., Mukhopadhyay, S., and Hardy, R.W. (2013) Encapsidation of host-derived factors correlates with enhanced infectivity of Sindbis virus.  J. Virol. 87(22):12216-12226. PMID 24006438

Tsvetkova, I. B., Cheng, F., Ma, X., Moore, A. W., Howard, B., Mukhopadhyay, S., and Dragnea, B. (2013) Fusion of mApple and Venus fluorescent proteins to the Sindbis virus E2 protein leads to different cell-binding properties.  Virus Res.177(2):138-146. PMID 23916968

Cheng, F., Tsvetkova, I. B., Khuong, Y., Moore, A., Arnold, R. J., Goicochea, N. L., Dragnea, B., and Mukhopadhyay, S. (2013) The packaging of different cargo into enveloped viral nanoparticles.  Mol. Pharm.10(1):51-8. PMID 22876758

Snyder, A. J. and Mukhopadhyay, S. (2012) The Alphavirus E3 protein functions in a clade-specific manner.  J Virol. 86(24):13609-20. PMID 23035234

Sokoloski, K. J., Hayes, C. A., Dunn, M. P., Balke, J. L., Hardy, R. W., and Mukhopadhyay, S. (2012) Sindbis Virus Infectivity Improves During the Course of Infection in Both Mammalian and Mosquito Cells. Virus Res167(1):26-33.  PMID 22484152

Snyder, A. J., Sokoloski, K. J., and Mukhopadhyay, S. (2012) Mutating conserved cysteines in the alphavirus E2 glycoprotein causes virus-specific assembly defects. J. Virol. 86(6):3100-11.  PMID 22238319

Cheng, F. and Mukhopadhyay, S. (2011) Generating enveloped virus-like particle with in vitro assembled cores. Virology. 413(2):153-60.  PMID 21334709

Lai, Y., Yi, G., Chen, A., Bhardwaj, K., Valverde, R. A., Zlotnick, A., Mukhopadhyay, S., Ranjith-Kumar, C. T., and Kao, C. C. (2011) Viral Double-strand RNA-binding Proteins Can Enhance Innate Immune Signaling By Toll-Like Receptor 3.  PlosOne. 6(10):e25837. PMID 22016778

Zlotnick, A. and Mukhopadhyay, S. (2011) Virus assembly, allostery, and antivirals.  Trends in Microbiology19(1):14-23.  PMID 21163649

Parrott, M. M., Sitarski, S. A., Arnold, R. J., Picton, L.. K., Hill, R. B., and Mukhopadhyay, S. (2009) Role of Conserved Cysteines in the Alphavirus E3 Protein.   J. Virol.  83(6): 2480-2490.  PMID 19109378

Goicochea, N. L, De, M., Rotello, V. M., Mukhopadhyay, S., and Dragnea, B. (2007) Core-like Particles of an Enveloped Animal Virus can Self-Assemble Efficiently on Artificial Templates. NanoLetters. 7(8):2281-90. PMID 1764536