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Indiana University Bloomington

BIOCHEMISTRY STUDENT AMBASSADORS

Welcome to our biochemistry student ambassador web page! We are a group of students at Indiana University who would like to assist you by answering any questions you have about the Interdisciplinary Biochemistry Graduate Program and about living in Bloomington, Indiana. We invite you to join us at Indiana University-Bloomington and become part of our exciting program.

We look forward to hearing from you!

Name Level Lab
Qian Dong Ph.D. Bauer
Chenglei Li Ph.D. Zlotnick
Sara Brandt Ph.D. DiMarchi
Yue Fu Ph.D. Giedroc
Siobhan Deis Ph.D. Dann
Alan Moore Ph.D. Mukhopadhyay
Vivekananda Kedage Ph.D. Hollenhorst
Ali Ozes PhD Nephew
Ryan Over PhD Michaels
Heidi Schindel PhD Bauer
Sundhar Subramanaian Ph.D. Dann

Qian DongHi! I am Qian Dong, a eighth year graduate student in Interdisciplinary Biochemistry program. I am now studying cyst formation in R. centenum in Bauer lab. Specifically, I am working on the structure and function of guanylyl cyclase. I came to IU from Nankai University, China, where I got my BS degree. IU is a very beautiful place, and a perfect place to do research.

If you have any question, feel free to contact me at dong3(at)indiana.edu. I will be more than glad to help!


Chenglei LiMy name is Chenglei Li and I just entered my eighth year as a Ph.D student in the Biochemistry Program. After I received my BS and MS in China, I decided to pursue my Ph.D degree in a more professional and well-equipped university. I then found this fantastic interdisciplinary biochemistry program in Indiana University, Bloomington. It has great scientists from various research areas and provides sufficient resources and supporting staff to help students to get through their research projects. Besides, the brand new home for this program—Simon Hall—has improved the research environment to a higher level. Beyond the study and research, the beautiful scenery and nice people in B-town also give people a good reason to enjoy a graduate life here. Currently I am working in Adam Zlotnick’s lab, mainly focusing on protein biochemical studies.

Feel free to contact me at li70(at)indiana.edu if you want to more details of this program or life here.


Sarh BrandtHi! My name is Sara Brandt, and I'm entering my sixth year in the Biochemistry program. I work in Richard DiMarchi's lab, where we work with insulin and insulin-related peptides, with a focus on improving the therapeutic index of current insulin-based therapies. I use synthetic and biosynthetic chemistries to create peptides and then test them in vitro. It's a fun mix of organic chemistry, microbiology, and cellular biology. I love the biochemistry program and I love living in Bloomington! When I'm not in the lab, I'm spending time at the children's science museum, Wonderlab, or enjoying the comedy club downtown. I would love to hear from prospective students and be happy to answer any questions! Please contact me at sjbrandt(at)indiana.edu


Yue FuHi my name is Yue Fu I am in the sixth year of the Biochemistry PhD program at Indiana University Bloomington. I got my B.S. from University of Science and Technology of China (USTC) before coming to Bloomington. This little nice town treats me well! The spring and fall here are the best! A little bit more about myself. I am working in the lab of David P. Giedroc (if you are interested in the tall skinny gentleman ,here is the link: http://www.indiana.edu/~dpglab/) My thesis project is investigating the mechanism of copper resistance in Streptococcus pneumoniae. It involves a lot of cool techniques, such NMR, crystallography and Mass spectrometry. And the best part of IU is you can do all of these on campus!
Oh, here is my contact information if you have ANY question! Feel free to email me at yuefu(at)indiana.edu


Siobhan DeisMy name is Siobhan Deis and I am a fourth year in the Interdisciplinary Biochemistry Program. I received my BA in Biochemistry from DePauw University in Greencastle, IN. I currently work in the Dann lab in the Chemistry department. My project focuses on the transport of novel antifolates via folate receptors and the inhibition of purine synthesis enzymes via these same antifolates. Folate receptors are overexpressed on cancer and auto inflammatory cells, therefore specific transport by these receptors will eliminate chemotherapy side effects due to attack of healthy cells. We use protein crystallography, binding assays and kinetic assays in order to observe the interactions. I have been really pleased with my experiences here at IU. The faculty is very engaged in their students work and always willing to help their own and other students. Also, Bloomington is a really fun town to live in. Downtown has many unique restaurants and places to shop all within walking distance of campus and the area is rich with state parks and lakes. If you have any questions about the program or Bloomington, don’t hesitate to e-mail me at smdeis(at)indiana.edu


Alan MooreMy name is Alan Moore and I am entering my fourth year of graduate study in Biochemistry Program. In the Mukhopadhyay lab, we study Alphaviruses. My research involves appropriating Alphavirus components for in vitro assembled virus-like nanoparticles. We're interested in harnessing the potential of virus-like nanoparticles to package a number of non-viral materials, and to perform beneficial, rather than harmful functions inside a host. We are also interested in using these nanoparticles to better understand the Alphavirus lifecycle, and other enveloped RNA viruses in general. Only in our interdisciplinary, multi-collaborative environment can the cutting edges of biochemistry, molecular biology, virology, and nanotechnology meet at the same bench. I think IU is a great place to pursue your graduate work for this very reason. It also helps that we have top notch facilities, extremely friendly and helpful faculty and staff, and a non-competitive environment conducive to collaboration and success. Bloomington also offers the benefits of a small midwestern town with plenty of ways to get out and enjoy nature, while simultaneously providing all the culturally enriching aspects of a liberal arts college town. Do you like music? art? …basketball? There's no shortage of things to see and do here. If you have any questions about the program or life in Bloomington, feel free to shoot me an email at mooreala(at)indiana.edu.


Vivekananda KedageHi all. I am Vivekananda Kedage, a fourth year graduate student in the Biochemistry department. I received my BSc and MSc from India. After my graduation I taught Medical Biochemistry to first year medical and dental students in Manipal University, India for a while and then came to US to earn a PhD degree. I am currently working in Dr. Peter Hollenhorst’s lab. We are trying to understand how ETS transcription factors regulate gene expression using prostate cancer as a model system. This family of 28 transcription factors regulates gene expression by binding to similar DNA sequences consisting of core ‘GGA’ motif. However, individual ETS proteins have a variety of biological roles. In particular, four ETS family members can act as oncogenes in prostate cancer. My project aims at dissecting how these four oncogenic ETS factors have unique transcriptional activating functions not present in other ETS family members. To address this problem we apply chromatin immunoprecipitation/next generation sequencing (ChIP-Seq), cell migration, in vitro DNA binding, and reporter assays. As we all know, we are currently living in the genomics era and members of the Biochemistry department have access to an in house Next-gen sequencing facility consisting of Roche/454 GS-FLX Titanium system, Illumina-MiSeq, and Microarray system, which are often used by graduate students to do their research. In addition to good research facilities, IUB has provided a number of recreational facilities for students. For example, IUB has two indoor sports facility, Student Recreational Sports Center (SRSC) and Health, Physical Education and Recreational center (HPER). In addition, IU has one of the best music schools in US, which hosts several music events throughout the year. If you have more questions you can email me at vkedage(at)indiana.edu, I would be more than happy to answer your questions.


Ali OzesMy name is Ali Ozes, and I am entering my fourth year of graduate school in the Interdisciplinary Biochemistry program here at IU. I received my BS from the University of California, Davis, in 2008. I am currently working in Dr. Kenneth Nephew’s lab on the mechanism of gene silencing by a long non-coding RNA called HOX antisense intergenic RNA, or more simply termed, ‘HOTAIR’. HOTAIR has been shown to interact with the Polycomb Repressive Complex 2 (PRC2) and guide it to specific gene targets and silence them with the incorporation of epigenetic silencing marks. PRC2 is well known to tightly regulate the activation of developmental pathways by epigenetic mechanisms to subsequently drive the proliferative capacity of cells. A consequence of epigenetic disruption of development pathways is thought to be a crucial point in the establishment of many types of cancers and even possibly cancer stem cells. Our lab discovered that HOTAIR, along with a number of other long non-coding RNAs, is highly over-expressed in breast and ovarian cancers. We also use the outstanding facilities here at IU and collaborate with other labs to perform cutting edge research and use new technologies like RNA-seq, deep-seq and ChIP-seq to uncover pathways in a variety of cancer cell types. If you ever get tired of doing research, the town of Bloomington has a lot to offer! With a variety of things to explore such as art and food festivals, plays, ballets and excellent musical performances featuring the world-renowned IU orchestra, as well as the charming Farmer’s Market on Saturday mornings. The open-minded people of Bloomington give the town its wonderful atmosphere. If you have any additional questions about the program or just graduate life in general, or want to take me on in a game of ping pong, don’t hesitate to email me at arozes(at)indiana.edu.


Ryan OverM Hello, my name is Ryan Over. I am a third year student in the Biochemistry Program. I earned my undergraduate degree at University of Rochester in Biochemistry. Before coming here to IU, I spent a year in Central Europe learning Czech and helping out a church plant in Brno by, among other things, teaching baseball and ESL. After rotating through a few labs, I joined the lab of Scott Michaels, where I am studying the nucleus, and in particular linker histones. As is probably true of many graduate students, I have high hopes that my research will be really important. Well…even if linker histones don’t turn out to be that important, I still find the nucleus a really interesting system and would love to figure out how it works! That’s my interest, but at IU there are plenty of labs to choose from. In addition, there are numerous facilities with knowledgeable staff to assist in a wide range of different projects. Though, my wife and I are still getting settled in Bloomington, we have really enjoyed all the events that happen in town and the nearby parks to explore. There really is something for just about anybody, whether sports, hiking areas, concerts or shows! If you have questions about the program, life in Bloomington or as a graduate student, or other random questions, then feel free to email me at rover(at)indiana.edu.


Heidi Schindel
Hello! I'm Heidi Schindel. I am a third year graduate student and a member of the Bauer lab. I went to IU for undergraduate school as well, during which I studied biology and sociology. My project is focused on the RegA/RegB two-component regulatory system in R. capsulatus. These proteins are responsible for recognizing changes in the environment (particularly oxygen concentration) and controlling the switch between aerobic and anaerobic (photosynthetic!) growth in this metabolically versatile bacterium. I am currently utilizing ChIP-Seq and RNA-Seq technologies to see the changes in gene expression that are controlled by the RegA transcription factor. I have lived in southern Indiana for my entire life and am very familiar with the area and all it has to offer. I enjoy traveling very much, and so far have backpacked throughout western and eastern Europe and studied German while in Austria. While I’m here planning more trips and studying biochemistry, the city of Bloomington continues to offer plenty of events and interesting activities to keep me thoroughly entertained. You can contact me at hsschind(at)indiana.edu if you have any questions!


Sundhar Hi, I am Sundharraman Subramanaian and I prefer to be called Sundhar. I am entering my third year and I work in the Dann lab. I earned my B.Tech degree in Industrial Biotechnology from Sastra University, India. I worked as a project trainee in International Center for Genetic Engineering and Biotechnology before joining IU. I am working to understand the c-di-GMP signaling pathway in Bacillus subtilus. The main aim of my project is the biochemical characterization of the proteins involved in c-di-GMP metabolism. I will be using Isothermal Calorimetry and protein crystallization to study the proteins. The best thing about the program is that it satisfies every one’s need and has a lot of labs to choose from. The centralized facility gives access to a variety of high-end instruments, which is a huge advantage. Everyone in the department is ready to help whenever there is an issue. As an international student I find Bloomington to be a pleasant and calm town. There are lots of options in the campus and in the town to fulfill your needs. I like Bloomington very much because, it has a plenty of good restaurants in the town and they offer delicious food from different cuisines. If, you have any questions please contact me at: sunsubra(at)indiana.edu. It’s always better to ask instead of assuming!