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Indiana University Bloomington

Pranav DanthiPranav Danthi

Assistant Professor, Chemistry

Office: Simon Hall 220B

Phone: 812/856-2449

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Lab Website

Education

Postdoctoral Research: Vanderbilt University, 2003-2008
Ph.D.: University of Arkansas for Medical Sciences, 2003

Research

Viral and Cellular Determinants of Virus-Induced Cell Death and Disease

Representative Publications

Berger, A.K., and P. Danthi (2013). Reovirus activates a caspase-independent cell death pathway. mBio 4: e00178-13.

Doyle, J.D., Danthi, P., Kendall, E.A., Ooms, L.S., Wetzel, J.D., and T. S. Dermody (2012). Molecular Determinants Of Proteolytic Disassembly Of The Reovirus Outer Capsid. Journal of Biological Chemistry. 287: 8029-8038.

Madren, J.A., Sarkar, P. and P. Danthi (2012). Cell entry-associated conformational changes in reovirus particles are controlled by host protease activity. Journal of Virology. 86: 3466-3473.

Barlan A.U, P. Danthi, and C.M. Wiethoff (2011). Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome. Virology 412: 306-314

Danthi, P. Enter the kill zone: Initiation of death signaling during virus entry (2011). Virology: 411:316-24

Danthi, P.*, A.J. Pruijssers, A. K. Berger, G. H. Holm, S. S. Zinkel, and T. S. Dermody*(2010). Bid regulates the pathogenesis of neurotropic reovirus. (* corresponding author) PLoS Pathogens 6:e1000980

Danthi P., K.M. Guglielmi, E. Kirchner, B. Mainou, T. Stehle, and T.S. Dermody (2010). From touchdown to transcription: The reovirus cell entry pathway. Current Topics in Microbiology and Immunology. 343:91-119

Sarkar, P. and P. Danthi. Determinants of strain-specific differences in reovirus cell entry (2010). Journal of Virology. 84:12723-32. Selected as spotlight article by the editors