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Indiana University Bloomington

James MckinlayJake mckinlay

Assistant Professor, Biology

Office: Jordan Hall A309

Phone: 812/855-0359

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Lab Website


BSc, University of British Columbia, 2001
MSc, Michigan State University, 2003
PhD, Michigan State University, 2006
Postdoctoral Fellow, University of Washington, 2007-2011


Microbial metabolism; bioprocessing; biofuels; 13C-metabolic flux analysis.

Representative Publications

McKinlay, JB and CS Harwood. 2011. Calvin cycle flux, pathway constraints and substrate redox state together determine the H2 biofuel yield in photoheterotrophic bacteria. mBio. 2: e00323-10. doi:10.1128/mBio.00323-10.

McKinlay, JB and CS Harwood. 2010. Carbon dioxide fixation as a central redox cofactor recycling mechanism in bacteria. Proceedings of the National Academy of Sciences USA. 107: 11669-11675.

McKinlay, JB and CS Harwood. 2010. Mini-review. Photobiological production of hydrogen gas as a biofuel. Current Opinion in Biotechnology. 21: 244-251.

McKinlay, JB, M Laivenieks, BD Schindler, AA McKinlay, S Siddaramappa, JF Challacombe, SR Lowry, A Clum, AL Lapidus, KB Burkhart, V Harkins and C Vieille. 2010. A genomic perspective on the potential of Actinobacillus succinogenes for industrial chemical production. BMC Genomics. 11: 680.

McKinlay, JB, Y Shachar-Hill, JG Zeikus, and C Vieille. 2007. Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analysis of 13C-labeled metabolic product isotopomers. Metabolic Engineering. 9: 177-192.

McKinlay, JB, C Vieille, and JG Zeikus. 2007. Mini-review. Prospects for a bio-based succinate industry. Applied Microbiology and Biotechnology. 76: 727-740.