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Indiana University Bloomington

David NelsonDavid Nelson

Professor, Department of Chemistry

Office: Jordan Hall A302

Phone: 812/856-2813

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Education

Ph.D., 2001 University of North Dakota School of Medicine
Postdoctoral Fellow 2001-2002 IUPUI, Indianapolis
Postdoctoral Fellow 2002-2006 Rocky Mountain Labs, NIH/NIAID

Research

Study of the chlamydial virulence factors and host response

Representative Publications

Kari L, Whitmire WM, Carlson JH, Crane DD, Reveneau N, Nelson DE, Mabey DC, Bailey RL, Holland MJ, McClarty G and HD Caldwell. 2008. Pathogenic diversity among Chlamydia trachomatis ocular strains in non human primates is affected by subtle genomic variations.  Journal of Infectious Disease, EPUB, Jan 16th.

Nelson DE, Taylor LD, Shannon, JG, Whitmire WM, Crane DD, McClarty G, Su H, Kari L and HD Caldwell. 2007. Phenotypic rescue of Chlamydia trachomatis growth in IFN-g treated mouse cells by irradiated Chlamydia muridarum.  Cellular Microbiology. 9(9):2289-98.

McClarty G, Caldwell HD and DE Nelson. 2007. Chlamydial interferon gamma immune evasion influences infection tropism. Current Opinion in Microbiology. 10:1-5.

Nelson DE, Crane DD, Taylor LD, Dorward DW, Goheen MM and HD Caldwell. 2006.  Inhibition of Chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes. Infection Immunity. 74(1):73-80.

Nelson DE, Virok DP, Wood H, Roshick C, Johnson RM, Whitmire WM, Crane DD, Steele-Mortimer O, Kari L, McClarty G and HD Caldwell.  2005 Chlamydial interferon gamma immune evasion is linked to host infection tropism.  PNAS. 102(30):10658-63.

Virok DP, Nelson DE, Whitmire WM, Crane DD, Goheen MM and HD Caldwell. 2005.  Chlamydial infection induces pathobiotype-specific protein tyrosine phosphorylation in epithelial cells. Infection Immunity. 73(4):1939-46.

Belland, RJ, Nelson DE, Crane DD, Hogan D, Sturdevant D, Beatty WL and HD Caldwell. 2003.  Transcriptome analysis of chlamydial growth during IFN-g mediated persistence and reactivation. PNAS. 100(26):15971-6.

Nelson DE, Ghosh A, Paulson A and KD Young.  2002. Contribution of membrane-binding and enzymatic domains of penicillin binding protein 5 to maintenance of uniform cellular morphology of Escherichia coli. Journal of Bacteriology. 184:3630-9. 

Nelson DE and KD Young.  2001.  Contributions of PBP 5 and DD-carboxypeptidase penicillin binding proteins to maintenance of cell shape in Escherichia coli.  Journal of Bacteriology. 183:3055-64.

Nelson DE and KD Young.  Penicillin binding protein 5 affects cell diameter, contour, and morphology of Escherichia coli. 2000. Journal of Bacteriology. 182(6):1714-21.