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Indiana University Bloomington

Martha OakleyMartha G. Oakley

Director of Graduate Studies, Molecular and Cellular Biochemistry Department

Associate Professor, Chemistry

Office: Simon Hall 320B

Phone: 812/855-4843

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B.A. Carleton College University 1986
B.A. Oxford University 1988.
Ph.D. California Institute of Technology 1994


Role of structural maintenance of chromosomes proteins in bacterial chromosome segregation and condensation; protein-protein and protein-nucleic acid interactions; microbial cell biology.

Representative Publications

Vincent M. Waldman, Tyler Stanage, Ian Norden, Martha G. Oakley (2015) “Structural Mapping of the Coiled-Coil Domain of a Bacterial Condensin and Comparative Analyses Across All Domains of Life Suggest Conserved Features of SMC Proteins,” Proteins: Struct., Funct., Bioinf. in press.

Seychelle M. Vos, Nichole K. Stewart, Martha G. Oakley, and James M. Berger (2013) “Structural Basis for the MukB•topoisomerase IV Interaction and Its Implications in vivo,” EMBO J. 32:2950.

Christopher S. Weitzel, Vincent M. Waldman, Travis A. Graham, Martha G. Oakley (2011) "A Repeated Coiled-Coil Interruption in the E. Coli Condensin," J. Mol. Biol.

Yinyin Li, Nichole Stewart, Anthony J. Berger, Seychelle Vos, Allyn J. Schoeffler, James M. Berger, Brian T. Chait and Martha G. Oakley, (2010) "The Escherichia coli Condensin MukB Stimulates Topoisomerase IV Activity by a Direct Physical Interaction," Proc. Natl. Acad. Sci., U.S.A. 107 (44): 18832.

Yinyin Li, Allyn J. Schoeffler, James M. Berger, Martha G. Oakley "The Crystal Structure of the Hinge Domain of the Escherichia coli Structural Maintenance of Chromosomes Protein MukB" (2010) J. Mol. Biol., 395 (1): 11-19.

Yinyin Li, Christopher S. Weitzel, Randy J. Arnold, Martha G. Oakley "Identification of Interacting Regions within the Coiled Coil of the Escherichia coli Structural Maintenance of Chromosomes Protein MukB," (2009) J. Mol. Biol. 391(1): 57-73