Martha G. Oakley
Director of Graduate Studies, Molecular and Cellular Biochemistry Department
Associate Professor, Chemistry
Office: Simon Hall 320B
B.A. Carleton College University 1986
B.A. Oxford University 1988.
Ph.D. California Institute of Technology 1994
Role of structural maintenance of chromosomes proteins in bacterial chromosome segregation and condensation; protein-protein and protein-nucleic acid interactions; microbial cell biology.
Christopher S. Weitzel, Vincent M. Waldman, Travis A. Graham, Martha G. Oakley (2011) "A Repeated Coiled-Coil Interruption in the E. Coli Condensin," J. Mol. Biol., in press.
Yinyin Li, Nichole Stewart, Anthony J. Berger, Seychelle Vos, Allyn J. Schoeffler, James M. Berger, Brian T. Chait and Martha G. Oakley, (2010) "The Escherichia coli Condensin MukB Stimulates Topoisomerase IV Activity by a Direct Physical Interaction," Proc. Natl. Acad. Sci., U.S.A. 107 (44): 18832–18837.
Yinyin Li, Allyn J. Schoeffler, James M. Berger, Martha G. Oakley "The Crystal Structure of the Hinge Domain of the Escherichia coli Structural Maintenance of Chromosomes Protein MukB" (2010) J. Mol. Biol., 395 (1): 11-19.
Yinyin Li, Christopher S. Weitzel, Randy J. Arnold, Martha G. Oakley "Identification of Interacting Regions within the Coiled Coil of the Escherichia coli Structural Maintenance of Chromosomes Protein MukB," (2009) J. Mol. Biol. 391(1): 57-73
Yinyin Li, Harmeet Kaur and Martha G. Oakley, "Probing the Recognition Properties of the Antiparallel Coiled Coil Motif from PKN by Protein Grafting" Biochemistry, 2008, 47 (51): 13564–13572
Oakley, M.G. and J.J. Hollenbeck, 2001, "The design of antiparallel coiled coils." Curr. Opin. Struct. Biol. 11 (4): 450-457.