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Indiana University Bloomington

Joe PomereningJoe Pomerening

Assistant Professor, Biology

Office: Simon Hall 043F

Phone: 812/ 855-1709

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Education

Postdoctoral Fellow, Stanford University School of Medicine, 2000-2006
Ph.D.,University of Illinois at Urbana-Champaign, 2000
B.S., Honors, University of Wisconsin-Madison, 1994

Research

Signal transduction pathways governing early embryonic and somatic cell cycles, and understanding the integration of feedback loops and other signaling elements in their M-phase control systems

Representative Publications

Pomerening J.R. (2008). " Uncovering mechanisms of bistability in biological systems." Curr Opin Biotechnol. 19(4):381-8.

Tsai T.Y., Choi Y.S., Ma W., Pomerening J.R., Tang C., Ferrell J.E. Jr. (2008). "Robust, tunable biological oscillations from interlinked positive and negative feedback loops." Science 321(5885):126-9.

Pomerening J.R., Ubersax J.A., Ferrell J.E. Jr. (2008). "Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF." Mol Biol Cell. 19(8):3426-41. Epub 2008 May 14.

Hansen, D.V.*, Pomerening, J.R.*, Summers, M.K., Miller, J.J., Ferrell, Jr., J.E., and Jackson, P.K. (2007). “Emi2 at the crossroads: where CSF meets MPF.” (*Co-first authors) Cell Cycle 6: 732-8.

Gong, D., Pomerening, J.R., Myers, J.W., Gustavsson, C., Jones, J.T., Hahn, A.T., Meyer, T., and Ferrell, Jr., J.E. (2007) “Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin B1.” Current Biology 17: 85-91.

Pomerening, J.R., Kim, S.Y., and Ferrell, Jr., J.E. (2005). “Systems-level Dissection of the Cell Cycle Oscillator: Bypassing Positive Feedback Produces Damped Oscillations.” Cell 122: 565-578.

Pomerening, J.R., Sontag, E.D., and Ferrell, Jr., J.E. (2003). “Building a Cell Cycle Oscillator: Hysteresis and Bistability in the Activation of Cdc2.” Nature Cell Biology 5: 346-51.

Pomerening, J.R., Valente, L., Kinzy, T.G., and Jacobs T.W. (2003). "Mutation of a Conserved CDK Site Converts a Metazoan Elongation Factor 1Bβ Subunit into a Replacement for Yeast eEF1Bα." Molecular Genetics and Genomics 269: 776-88.