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Indiana University Bloomington

Julia van KesselJulia van Kessel

Assistant Research Scientist, Molecular and Cellular Biochemistry Department

Office: Simon Hall 400B

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Education

B.S. (2003), Utica College of Syracuse University, Biology
Ph.D. (2008), University of Pittsburgh, Molecular, Cellular, and Developmental Biology
Postdoctoral Fellowship (2009-2013), Princeton University, Molecular Genetics and Microbiology

Research

Bacterial cell-cell communication (quorum sensing); mechanisms of gene regulation in bacteria; regulation of bacterial stress response; dynamics of global transcriptional regulation.

Representative Publications

van Kessel JC, Ulrich LE, Zhulin IB, Bassler BL. (2013) Analysis of activator and repressor functions reveals the requirements for transcriptional control by LuxR, the master regulator of quorum sensing in Vibrio harveyi. mBio 4 (4): pii: e00378-13.
van Kessel JC, Rutherford ST, Shao Y, Utria AF, Bassler BL. (2013) Individual and Combined Roles of the Master Regulators AphA and LuxR in Control of the Vibrio harveyi Quorum-Sensing Regulon. Journal of Bacteriology 195 (3): 436-443.
Rutherford ST, van Kessel JC, Shao Y, and Bassler BL. (2011) AphA and LuxR/HapR reciprocally control quorum sensing in vibrios. Genes and Development 25 (4): 397-408.
van Kessel JC, Marinelli LM, and Hatfull GF. (2008) Recombineering mycobacteria and their phages. Nature Reviews Microbiology 6 (11): 851-857.
Marinelli LM, Oldfield L, Payne K, Swiganova S, van Kessel JC, and Hatfull GF. (2008) BRED: a simple and powerful tool for constructing mutant and recombinant bacteriophage genomes. PLOS One 3 (12): e3957.
van Kessel JC and Hatfull GF. (2008) Efficient point mutagenesis in mycobacteria using single-stranded DNA recombineering: characterization of anti-mycobacterial drug targets. Molecular Microbiology 67 (5): 1094-1107.
van Kessel JC and Hatfull GF. (2008) Mycobacterial Recombineering, in Davis GD and Kayser KJ, Chromosomal Mutagenesis. Methods in Molecular Biology 435: 203-215.
van Kessel JC and Hatfull GF. (2007) Recombineering in Mycobacterium tuberculosis. Nature Methods 4 (2): 147-152.