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Indiana University Bloomington

Work by biochemists increasingly forms the basis of new techniques and treatments employed by physicians to treat disease; in IU's Molecular and Cellular Biochemistry Department, our priority area is structural virology and virus assembly.

students in labs

Biochemistry Seminar Series

Fridays in CH 033 at 2:30 p.m. (unless otherwise noted)

To propose a guest speaker, please contact a co-chair of the seminar series:

  • MCB: Prof. Adam Zlotnick
  • Chemistry: Prof. Charles Dann III
  • Biology or Med. Science: Prof. Adam Zlotnick and Prof. Charles Dann III

Fall 2015

Sept 4 Mindy Steiniger (University of Missouri-St. Louis)"Protein-Protein Interactions Required for Histone mRNA 3’ end Processing in Drosophila" Host: Hundley
Sept 18 Lois Pollack (Cornell University) "Pioneering New Methods for Exploring DNA or RNA Binding Partners" Host: Giedroc
Sept 25
SI 001
Dennis Discher (University of Pennsylvania) "Foreign vs Self Recognition of Materials & Cells by Macrophages" Host: Yan Yu
Sept 25 Inorganic Alumni Symposium
Oct 2 George Lorimer (UMD-College Park) "Optimizing Protein Folding with a Parallel-Processing, Iterative Annealing Machine" Host: Lingling
Oct 9 Fall Break-Watanabe Symposium on 10/10
Oct 16 Yong Xiong (Yale University)"A Structural Biology View of HIV Suppression by Host Antiviral Factors and Viral Immune Evasion Strategies" Host: Niu
Oct 30 Jianming Hu (Penn State University)"Hepatitis B Virus Capsid Assembly, Maturation, and Disassembly" Host: Zlotnick
Nov 6 Rui Zhao (University of Colorado-Boulder)"Targeting the Six1/Eya Transcriptional Complex for Breast Cancer Therapy" Host: Giedroc
Nov 13 Tanja Kortemme (UCSF)"Computational Design of Modified and New Protein Functions - Sensors for New Signals and Controllable Machines" Host: Giedroc *Visit Co-sponsored by NIH-Funded QCB Training Program and IU MCB Department
Nov 20 Anna Kashina (University of Pennsylvania)"Protein Arginylation as the Global Regulator of Cell Migration and Protein Function" Host: Ke Hu
Nov 27 Thanksgiving Break
Dec 4 Samy Meroueh (IU School of Medicine)"Small Molecules to Explore Protein-Protein Interactions in Cancer Metastasis" Host: Charles Dann
Dec 11 Kirill Afonin (UNC-Charlotte)"Multifunctional RNA and DNA Nanoparticles for Biomedical Applications" Host: Dragnea

Spring 2016

Jan 15 Malcolm Winkler (Professor of Biology; Dept. of Biology IUB) "Sizing Up Streptococcus pneumoniae: Peptidoglycan Biosynthesis Mechanisms That Determine Cell Shape, Size, and Chaining of Gram-positive Ovococcus Bacterial Pathogens"
Feb 5 Jiajie Diao (University of Cincinnati )"Ultra-sensitive single-molecule quantification of DNA epigenetic modifications" Host: Ressl
Feb 12 Brandt Eichman (Vanderbilt University)"A New Paradigm for DNA Repair Revealed through Structural Biology of Bacterial DNA glycosylases" Host: Bochman
Feb 19 Caryn Outten (University of South Carolina)"Fe-S Clusters as Sensors of Cellular Iron Status" Host: David Giedroc
Feb 26 Anja Bielinsky (University of Minnesota)"SUMO and Ubiquitin Networks Promoting Replication Stress Tolerance" Host: Matt Bochman
Mar 4 Patrick Sung (Yale University)"Role of the BRCA2-DSS1 Complex in Homologous Recombination" Host: Niu
Mar 11 Sandra Weller (University of Connecticut)"Herpes Simplex Virus Must Navigate a Hostile Environment to Establish a Lytic Infection" Host: Tuli
Mar 18 Spring Break
Mar 25 Steven Boxer (Stanford University)"Vibrational Stark Spectroscopy Connects Electrostatics to Catalytic Rates at Enzyme Active Sites" Host: Yan Yu
Apr 8 Christine Dunham (Emory University)"The role of bacterial toxin-antitoxin complexes in translational inhibition during stress" Host: Tuli
Apr 15 Aaron Straight (Stanford Medical School)"RNA dependent control of chromatin silencing" Host: Oakley
Apr 22 Amy Palmer (University of Colorado)"Development of fluorescent tools for live cell imaging: how quantitative imaging led to exploration of zinc ions as cellular messengers " Host: Giedroc
May 6 Reza Khayat (The City College of New York)"Mechanism of cellular recognition by porcine circovirus 2" Host: Zlotnick

BMB Research Club Series

Wednesdays at 12:30 p.m. - 1:30 p.m. in SI 001
(unless otherwise noted)

Spring 2016:

Feb 3 Virginia Smith (Dragnea) "SNARE Mediated Vesicle Fusion: A Future Assay for Viral Assembly"
Feb 17 Vivekananda Kedage (Hollenhorst) "ERG-EZH2 mediated gene repression is relieved by ERK phosphorylation of ERG"
Feb 24 Ali Ozes (Nephew) "Targeting the long non-coding RNA HOTAIR with tumor-specific peptides to reverse chemotherapy resistance"
Mar 2 Andrew Elliot (Shaw) "Seeing biology in a new light with Light Sheet Microscopy"
Mar 23 Haley Hoover (Kao) "Brome Mosaic Virus Phosphorylation and Infection of Rice"
Mar 30 Chinmayi Chandrasekhara (Pikaard) "A Duplicated Nucleolin Gene with Antagonistic Activity Is Required for Chromatin Organization of Silent 45S rDNA in Arabidopsis"
April 6 Ryan Over (Michaels) "MicroProtein-Mediated Recruitment of CONSTANS into a TOPLESS Trimeric Complex Represses Flowering in Arabidopsis"
April 13 Wan-Hung Lee (Hohmann)"Disrupting protein-protein interactions as novel analgesics"
April 20 Sundhar Subramanian (Dann) "Understanding the role of the c-di-GMP receptor DgrA in the regulation of Bacillus subtilis swarming motiilty"
April 27 Haley Hoover (Kao) "Virus Coat Protein Phosphorylation: A Common Theme"
May 4 Kayla Bell (Cochran) "Directional Regulation of the Yeast Kinesin-5, Cin8"
May 11 Heidi Schindel (Bauer) "Bacterial Microcompartments and their Potential as Platforms for Metabolic Engineering"


Upcoming Ph.D. Defense/Upcoming MA Defense/Prelims

Upcoming Ph.D. Defense:

Aug 5
SI 001
Natasha Gebhart (Hardy) "The Identification and Characterization of RNA-Binding Proteins Involved in Alphavirus Replication"  
Aug 19
SI 001
Melissa Illingworth (Chen) "Activation of Folding Function of the Single Ring Groelsr"  
Sept 4
SI 101
Joseph Kumka (Bauer) "Global Transcriptional Control of Photosynthetic and Aerobic Events in Rhodobacter Capsulatus"  
Dec 15
SI 001
Erkin Kuru (VanNieuwenhze) “Novel Ways for Decorating Bacterial Cell Walls Advance Fundamental Knowledge About Bacterial Growth”  
Jan 26
IMU Oak Rm
Rachel Samson (Bell) "The Regulated Recruitment of the MCM Helicase to Origins of Replication"  
May 5 2:00pm SI 001 Jiangchuan Shen (Giedroc) "Characterization of enzymes involved in hydrogen sulfide (H2S) detoxification and H2S-reactive nitrogen species crosstalk in bacterial pathogens"  
May 12 2:00pm SI 001 John Lisher (Giedroc) "Probing manganese homeostasis and the oxidative stress response in Streptococcus pneumoniae"  
May 25 2:30pm C 033 Siobhan Deis (Dann) "Biochemical and Biophysical Analysis of Antifolate Drugs with Disease Tissue Specificity"  
July 27 10:00am JH 248 Chinmayi Chandrasekhara (Pikaard) "TBA"  

Masters Defense:

TBA TBA () "TBA"  


Aug 21
SI 001
David Dudek (Daleke) "ATP8A1, A P4-Type Atpase and Phosphatidylserine 'Flippase' with sn-1,2-Stereospecificity"  
Nov 10
SI 001
Cody Rogers (Bochman) "RecQ4 Family Helicases are Multifunctional Genome Caretakers"  
Nov 11
CH C127
Benjamin Walker (Cochran) "Biophysical Details of an Unconventional Drosophila Kinesin"  
Nov 12
SI 001
Hui Peng (Giedroc) "Intersection of Reactive Nitrogen and Sulfur Species in Staphylococcus Aureus"  
Nov 24
SI 001
Jiefei Wang (Giedroc) "Biochemical Investigation of the Zinc-limitation Response in Acinetobacter Baumannii"  
Dec 1
SI 001
Brian Towell (Tuli) "Elucidating the Role of Interdimer Contacts in Alphavirus Spike Assembly"  
Dec 8
JH 001
Nick Pulliam (Nephew) "The Novel Combination of DNMTi and PARPi in BRCA-proficient Ovarian Cancer"  
Dec 9
CH C033
Yen-Pang Hsu (VanNieuwenhze) "Analysis of Bacterial Peptidoglycan Synthesis and Dynamics through Fluorescent Molecule Probing"  
Dec 11
SI 001
Michael Priestley (VanNieuwenhze) "Functionalizing the Hepatitis B Virus Capsid with a Small Molecule"