Indiana University Bloomington

Neuroscience
Neuroscience
Heather B. Bradshaw

Heather B. Bradshaw

B.S., Florida State University, 1994
Ph.D., Florida State University, 2001
Postdoctoral Fellow, Brown University and Indiana University 2001-2007

Email address: hbbradsh(at)indiana.edu

Research Interests

My research focuses on how physiological and biochemical aberrations in the reproductive system leads to sexual dysfunction disorders and chronic pelvic pain in women.

Representative Publications

Bradshaw, H.B., Temple, J.L., Wood, E., and Berkley, K.J. (1999). Estrous variations in behavioral responses to vaginal and uterine distention in the rat. Pain, 82: 187-197.

Temple, J.L., Bradshaw, H.F., Wood, E., and Berkley, K.J. (1999). Effects of hypogastric neurectomies on escape responses to uterine distention in the rat. Pain, Suppl 6: S13-20.

Bradshaw, H., Miller, J., Ling, Q., Malsnee, K., and Ruda, M.A. (2000). Sex differences and phases of the estrous cycle alter the response of spinal cord dynorphin neurons to peripheral inflammation and hyperalgesia. Pain, 85: 93-99.

Bradshaw, H.B. and Berkley, K.J. (2000). Estrous changes in responses of rat gracile nucleus neurons to stimulation of skin and pelvic viscera. Journal of Neuroscience, 20: 7722-7727.

Berkley, K.J., Cason, A., Jacobs, H., Bradshaw, H., and Wood, E. (2001). Vaginal hyperalgesia in a rat model of endometriosis. Neuroscience Letters, 306: 185-188.

Bradshaw, H.B. and Berkley, K.J. (2002). Estrogen replacement reverses ovariectomy-induced vaginal hyperalgesia in the rat. Maturitas, 41: 157-165.

Bradshaw, H.B. and Berkley, K.J. (2003). The influence of ovariectomy with or without estrogen replacement on responses of rat gracile nucleus neurons to stimulation of hindquarter skin and pelvic viscera. Brain Research, 986: 82-90.

Fernandez-Rodriguez, C.M., Romero, J., Petros, T.J., Bradshaw, H., Gasalla, J.M., Gutierrez, M.L., Lledo, J.L., Santander, C., Fernandez, T.P., Tomas, E., Cacho, G., and Walker, J.M. (2004). Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis. Liver International, 24: 477-483.

Bradshaw, H.B. and Walker, J.M. (2005). The expanding field of cannabimimetic and related lipid mediators. British Journal of Pharmacology, 144: 459-465.

Walker, J.M., Krey, J.F., Chen, J.S., Vefring, E., Jahnsen, J.A., Bradshaw, H., and Huang, S.M. (2005). Targeted lipidomics: fatty acid amides and pain modulation. Prostaglandins & Other Lipid Mediators, 77: 35-45.

Bradshaw, H.B, Rimmerman, N., Krey, J.F., and Walker, J.M. (2006). Sex and hormonal cycle differences in brain levels of pain-related cannabimimetic lipid mediators. American Journal of Physiology, Regulatory, Integrative and Comparative Physiology, 291: R349-358.

Tan, B., Bradshaw, H.B, Rimmerman, N., Hughes, H.F., Yu, Y.W., Krey, J.F., Monn, F.M., Chen, J., Hu, S.S-J., O'Dell, D.K., and Walker, J.M. (2006). Targeted lipidomics: discovery of new fatty acyl amides. AAPS Journal, 8: E461-465.

Burnstein, S.H., Adams, J.K., Bradshaw, H.B, Fraioli, C., Rossetti, R.G., Salmonsen, R.A., Shaw, J.W., Walker, J.M., Zipkin, R.E., and Zurier, R.B. (2007). Potential anti-inflammatory actions of the elmiric (lipoamino) acids. Bioorganic & Medicinal Chemistry, 15: 3345-3355.