Andrea Hohmann

Ph.D. Brown University, 1996
Sc.M. Brown University, 1993
B.Sc. Brown University, 1988

Email address: hohmanna(at)indiana.edu

Research Interests

My research has focused on understanding pain modulation from a neurochemical perspective. The discovery of cannabinoid receptors and identification of brain constituents that act at these receptors established the existence of an endogenous cannabis-like (endocannabinoid) transmitter system. My research has identified functional roles of the endocannabinoid system in the nervous system and mapped it's distribution in sensory pathways. My research has identified enzymes implicated in endocannabinoid deactivation as novel therapeutic targets. My laboratory strives to maximize the therapeutic potential of endocannabinoid signaling systems while minimizing unwanted central nervous system side-effects (e.g. psychoactivity and addiction). My research program combines behavioral, drug self-administration, neuroanatomical, neurophysiological and molecular approaches to study cannabinoid mechanisms for suppression of pain and stress responsiveness.

Representative Publications

Please search for "A. G. Hohmann" on PubMed to view recent publications from this investigator.

Nackley, A.G., Makriyannis, A. and Hohmann, A.G. (2003) Selective activation of cannabinoid CB2 receptors suppresses spinal Fos protein expression and pain behavior in a rat model of inflammation. Neuroscience 119: 747-757.

Nackley, A.G., Zvonok, A.M., Makriyannis, A., and Hohmann, A.G. (2004) Activation of cannabinoid CB2 receptors suppresses C-fiber responses and windup in spinal wide dynamic range neurons in the absence and presence of inflammation. Journal of Neurophysiology 92: 3562-3574.