Indiana University Bloomington

Neuroscience
Neuroscience
Laura L. Murray

Laura L. Murray

B.Sc., University of Western Ontario, 1987
M.S., Minot State University, 1988
Ph.D., University of Arizona, 1994

Email address: lmurray(at)indiana.edu

Research Interests

Dr. Murray's general research interest is the cognitive and neural bases of adult neurogenic communication disorders. She is particularly interested in determining how deficits in cognitive processes other than language, such as attention and memory, interact with communication skills. Her work describes and compares the integrity of language and cognition in adults with left or right hemisphere brain-damage, traumatic brain injury, or progressive diseases such as Alzheimer's, Huntington's, and Parkinson's Diseases. Current projects compare dual-task performances of adults with aphasia and adults with right hemisphere brain-damage to examine whether site of lesion or brain-damage in general is most detrimental to attentional skills and to associations between attention and language processes. Additionally, several single-subject research projects are ongoing that focus on developing new or modifying existing treatment protocols to remediate linguistic and cognitive impairments in adults with aphasia as well as other patient populations. Previous research has included: (a) relating patterns of discourse production (i.e., syntactic, semantic, and pragmatic levels) in progressive disorders to the degree of cognitive, behavioral, and/or motor impairment to identify possible underlying sources of communication impairment, and consequently to develop interventions to improve or maintain effective interaction between brain-damaged patients and their daily communicative partners; (b) resolving the clinical diagnostic dilemma of distinguishing reversible pseudodementia from the early stages of irreversible dementia by quantitatively and qualitatively comparing the language and attention skills of elderly adults with these disorders; and (c) quantifying and qualifying linguistic and cognitive changes associated with normal aging.

Representative Publications

Murray, L.L. (1999) Attention and aphasia: Theory, research and clinical implications. Aphasiology, 13, 91-112.

Murray, L.L. and Stout, J.C. (1999) Discourse comprehension in Huntington's and Parkinson's Diseases. American Journal of Speech-Language Pathology, 8, 137-148.

Murray, L.L. (2000) Spoken language production in Huntington's and Parkinson's diseases. Journal of Speech, Language, and Hearing Research, 43, 1350-1366.

Murray, L.L. (2000) The effects of varying attentional demands on the word-retrieval skills of adults with aphasia, right hemisphere brain-damage or no brain-damage. Brain and Language, 72, 40-72.

Murray, L. L. and Ray, A. H. (2001). A comparison of relaxation training and syntax stimulation for chronic nonfluent aphasia. Journal of Communication Disorders, 34, 87-113.

Murray, L. L. (2002) Cognitive distinctions between depression and early Alzheimer's disease in the elderly. Aphasiology, 16, 573-586.

Murray, L.L., Dickerson, S., Lichtenberger, B. and Cox, C. (2003) Effects of toy stimulation on the cognitive, communicative, and emotional functioning of adults in the middle stages of Alzheimer's disease. Journal of Communication Disorders, 36, 101-127.

Murray, L.L. (2004) Cognitive treatments for aphasia: Should we and can we help attention and working memory problems? Medical Journal of Speech-Language Pathology, 12, xxi-xxxviii.

Murray, L.L. and Kim, H.-Y. (2004) A review of select alternative treatment approaches for acquired neurogenic disorders: Relaxation therapy and acupuncture. Seminars in Speech and Language, 25, 133-149.

Murray, L.L. and Kean, J. (2004) Resource theory and aphasia: Time to abandon or time to revise: Aphasiology, 18, 830-835.

Murray, L.L. and Clark, H.M. (2005) Neurogenic disorders of language: Theory driven clinical practive. Clifton Park, NY: Thomson Delmar Learning.

Murray, L.L., Keeton, R.J. and Karcher, L. (2006) Treating attention in mild aphasia: Evaluation of attention process training-II. Journal of Communication Disorders, 39, 37-61.

Murray, L.L. (2006). Cardiovascular disease: Implications for speech-language pathologists and audiologists. ASHA Leader, 11, 10-11, 22-23.

Murray, L.L., Timberlake, A., and Eberle, R. (2007) Treatment of Underlying Forms in a discourse context. Aphasiology, 21, 139-163.

Raymer, A.M., Beeson, P., Holland, A., Maher, L.M., Martin, N., Murray, L., Rose, M., Thompson, C. K., Turkstra, L., Altmann, L., Boyle, M., Conway, T., Hula, W., Kearns, K., Kendall, D., Rapp, B., Simmons-Mackie, N., & Gonzalez-Rothi, L.J. (2008). Translational research in aphasia: From neuroscience to neurorehabilitation. Journal of Speech, Language, and Hearing Research, 51, S259-S275.

Murray, L.L. (2008) Language and Parkinson¹s disease. Annual Review of Applied Linguistics, 28, 1-15.

Lorenzen, B., & Murray, L.L. (2008). Bilingual aphasia: A theoretical and clinical review. American Journal of Speech-Language Pathology, 17, 21-19.

Murray, L.L. (2010). Distinguishing clinical depression from early Alzheimer¹s disease in the elderly: Can narrative analysis help? Aphasiology, 24(6), 928-939.

Miller, E., Murray, L., Richards, L., Zorowitz, R., Bakas, T., Clark, P., & Sullivan, K. (2010). Comprehensive overview of nursing and interdisciplinary rehabilitation care of the stroke patient. Stroke, 41, DOI: 10.1161/STR.0b013e3181e7512b.

Kean, J., Trzepacz, P. T., Murray, L. L., Abell, M., & Trexler, L. E. (2010). Initial validation of a brief provisional diagnostic scale for delirium. Brain Injury, 24(10), 1222-1230.

Murray, L. L. (in press). Direct and indirect treatment approaches for addressing short-term or working memory deficits in aphasia. Aphasiology.