B.1.12 Compare and contrast the form and function of prokaryotic and eukaryotic cells.

Molecules and Cells

7.4.1Explain that similarities among organisms are found in external & internal anatomical features, including specific characteristics at the cellular level, such as the number of chromosomes. Understand that these similarities are used to classify organisms since they may be used to infer the degree of relatedness among organisms.

7.4.3 Explain how, in sexual reproduction, a single specialized cell from a female merges with a specialized cell from a male & this fertilized egg carries genetic information from each parent & multiplies to form the complete organism.

7.4.4 Explain that the basic functions of organisms, such as extracting energy from food & getting rid of wastes, are carried out within the cell & understand that the way which cells function is similar in all organisms.

7.4.5 Explain how food provides the fuel & the building material for all organisms.

7.4.6 Describe how plants use the energy from light to make sugars from carbon dioxide & water to produce food that can be used immediately or stored for later use.

7.4.7 Describe how organisms that eat plants break down the plant structures to produce the materials & energy that they need to survive, & in turn, how they are consumed by other organisms.

8.4.5 Explain that energy can be transferred from one form to another in living things.

8.4.6 Describe how animals get their energy from oxidizing their food & releasing some of this energy as heat.

B.1.2 Explain that every cell is covered by a membrane that controls what can enter and leave the cell. Recognize that in all but quite primitive cells, a complex network of proteins provides organization and shape. In addition, understand that flagella and/or cilia may allow some Protista, some Monera, and some animal cells to move.

B.1.3 Know and describe that within the cell are specialized parts for the transport of materials, energy capture and release, protein building, waste disposal, information feedback, and movement. In addition to these basic cellular functions common to all cells, understand that most cells in multicellular organisms perform some special functions that others do not.

B.1.4 Understand and describe that the work of the cell is carried out by the many different types of molecules it assembles, such as proteins, lipids, carbohydrates, and nucleic acids.

B.1.5 Demonstrate that most cells function best within a narrow range of temperature and acidity. Note that extreme changes may harm cells, modifying the structure of their protein molecules and therefore, some possible functions.

B.1.6 Show that a living cell is composed mainly of a small number of chemical elements - carbon, hydrogen, nitrogen, oxygen, phosphorous, and sulfur. Recognize that carbon can join to other carbon atoms in chains and rings to form large and complex molecules.

B.1.7 Explain that complex interactions among the different kinds of molecules in the cell cause distinct cycles of activities, such as growth and division. Note that cell behavior can also be affected by molecules from other parts of the organism, such as hormones.

B.1.8 Understand and describe that all growth and development is a consequence of an increase in cell number, cell size, and/or cell products. Explain that cellular differentiation results from gene expression and/or environmental influence. Differentiate between mitosis and meiosis.

B.1.9 Recognize and describe that both living and nonliving things are composed of compounds, which are themselves made up of elements joined by energy-containing bonds, such as those in ATP.

B.1.10 Recognize and explain that macromolecules such as lipids contain high energy bonds as well.

Developmental and Organismal Biology

7.4.11 Explain that viruses, bacteria, fungi, & parasites may infect the human body & interfere with normal body functions. Recognize that a person can catch a cold many times because there are many varieties of cold viruses that cause similar symptoms.

B.1.11 Describe that through biogenesis all organisms begin their life cycles as a single cell and that in multicellular organisms, successive generations of embryonic cells form by cell division.

B.1.13 Explain that some structures in the modern eukaryotic cell developed from early prokaryotes, such as mitochondria, and in plants, chloroplasts.

B.1.14 Recognize and explain that communication and/or interaction are required between cells to coordinate their diverse activities.

B.1.15 Understand and explain that, in biological systems, structure and function must be considered together.

B.1.16 Explain how higher levels of organization result from specific complexing and interactions of smaller units and that their maintenance requires a constant input of energy as well as new material.

B.1.17 Understand that and describe how the maintenance of a relatively stable internal environment is required for the continuation of life and explain how stability is challenged by changing physical, chemical, and environmental conditions, as well as the presence of disease agents.

B.1.18 Explain that the regulatory and behavioral responses of an organism to external stimuli occur in order to maintain both short- and long-term equilibrium.

B.1.19 Recognize and describe that metabolism consists of the production, modification, transport, and exchange of materials that are required for the maintenance of life.

Genetics

8.4.2 Describe that in some organisms, such as yeast or bacteria, all genes come from a single parent, while in those that have sexes, typically half of the genes come from each parent.

8.4.7 Recognize & explain that small genetic differences between parents & offspring can accumulate in successive generations so that descendants are very different from their ancestors.

B.1.21 Understand and explain that the information passed from parents to offspring is transmitted by means of genes which are coded in DNA molecules.

B.1.23 Understand that and describe how inserting, deleting, or substituting DNA segments can alter a gene. Recognize that an altered gene may be passed on to every cell that develops from it, and that the resulting features may help, harm, or have little or no effect on the offspring’s success in its environment.

B.1.24 Explain that gene mutations can be caused by such things as radiation and chemicals. Understand that when they occur in sex cells, the mutations can be passed on to offspring; if they occur in other cells, they can be passed on to descendant cells only.

B.1.26 Demonstrate how the genetic information in DNA molecules provides instructions for assembling protein molecules and that this is virtually the same mechanism for all life forms.

B.1.29 Understand that and explain how the actions of genes, patterns of inheritance, and the reproduction of cells and organisms account for the continuity of life, and give examples of how inherited characteristics can be observed at molecular and whole-organism levels - in structure, chemistry, or behavior.

Evolution

B.1.30 Understand and explain that molecular evidence substantiates the anatomical evidence for evolution and provides additional detail about the sequence in which various lines of descent branched off from one another.

B.1.33 Describe how life on Earth is thought to have begun as simple, one-celled organisms about 4 billion years ago. Note that during the first 2 billion years, only single-cell microorganisms existed, but once cells with nuclei developed about a billion years ago, increasingly complex multicellular organisms evolved.

B.1.34 Explain that evolution builds on what already exists, so the more variety there is, the more there can be in the future. Recognize, however, that evolution does not necessitate long-term progress in some set direction.

B.1.35 Explain that the degree of kinship between organisms or species can be estimated from the similarity of their DNA sequences, which often closely matches their classification based on anatomical similarities. Know that amino acid similarities also provide clues to this kinship.

Ecology

7.4.2 Describe that all organisms, including the human species, are part of & depend on two main interconnected global food webs, the ocean food web & the land food web.

7.4.8 Understand & explain that as any population of organisms grows, it is held in check by one or more environmental factors. These factors could result in depletion of food or nesting sites and/or increased loss to increased numbers of predators or parasites. Give examples of some consequences of this.

7.4.9 Describe how technologies having to do with food production, sanitation, & disease prevention have dramatically changed how people live & work & have resulted in changes in factors that affect the growth of human population.

8.4.4 Describe how matter is transferred from one organism to another repeatedly & between organisms & their physical environment.

8.4.8 Describe how environmental conditions affect the survival of individual organisms & how entire species may prosper in spite of the poor survivability or bad fortune of individuals.

B.1.37 Explain that the amount of life any environment can support is limited by the available energy, water, oxygen, and minerals, and by the ability of ecosystems to recycle the residue of dead organic materials. Recognize, therefore, that human activities and technology can change the flow and reduce the fertility of the land.

B.1.44 Describe the flow of matter, nutrients, and energy within ecosystems.

B.1.45 Recognize that and describe how the physical or chemical environment may influence the rate, extent, and nature of the way organisms develop within ecosystems.

B.1.46 Recognize and describe that a great diversity of species increases the chance that at least some living things will survive in the face of large changes in the environment.

Historical

7.7.1 Understand /explain that throughout history, people have created explanations for disease. Note that some held that disease had spiritual causes, but that the most persistent biological theory over the centuries was that illness resulted from an imbalance in the body fluids. Realize that the introduction of germ theory by Louis Pasteur & others in the nineteenth century led to the modern understanding of how many diseases are caused by microorganisms, such as bacteria, viruses, yeasts, & parasites.

7.7.2 Understand & explain that Louis Pasteur wanted to find out what caused milk & wine to spoil. Note that he demonstrated that spoilage & fermentation occur when microorganisms enter from the air, multiply rapidly, & produce waste products, with some desirable results, such as carbon dioxide in bread dough, & some undesirable, such as acetic acid in wine. Understand that after showing that spoilage could be avoided by keeping germs out or by destroying them with heat, Pasteur investigated animal diseases & showed that microorganisms were involved in many of them. Also note that other investigators later showed that specific kinds of germs caused specific diseases.

7.7.3 Understand & explain that Louis Pasteur found that infection by disease organisms (germs) caused the body to build up an immunity against subsequent infection by the same organisms. Realize that Pasteur then demonstrated more widely what Edward Jenner had shown for smallpox w/o understanding the underlying mechanism: that it was possible to produce vaccines that would induce the body to build immunity to a disease without actually causing the disease itself.

7.7.4 Understand/describe that changes in health practices have resulted from the acceptance of the germ theory of disease. Realize that before germ theory, illness was treated by appeals to supernatural powers or by trying to adjust body fluids through induced vomiting or bleeding. Note that the modern approach emphasizes sanitation, the safe handling of food & water, the pasteurization of milk, quarantine, & aseptic surgical techniques to keep germs out of the body; vaccinations to strengthen the body’s immune system against subsequent infection by the same kind of microorganisms; & antibiotics & other chemicals & processes to destroy

microorganisms.

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