Instrumentation


List of Equipment

Click an instrument's name for image and details

Instrument Make Model Major Applications
Microscale Thermophoresis NanoTemper Monotlith NT.115 Blue/Red Quantitation of biomolecular interaction strength
Fluorometer PerkinElmer LS50B Structure, folding, binding thermodynamics and kinetics
Tabletop Ultracentrifuge Beckman Coulter

Optima Max-XP

Small volume ultracentrifugation. Zonal and continuous flow separation methods.

Isothermal Titration Calorimeter TA Instruments

nanoITC

Thermodynamics of binding

Variable Mode Imaging System

GE Life Sciences

Typhoon 9210 and 9500

Quantitation of gels, plates, autoradiograms, etc.

Circular Dichroism Spectrometer Jasco

J-715

Structure and interactions

UV / Visible Spectrometer

Varian

Cary 100 Bio

Thermodynamics of folding and kinetic assays, oligonucleotide melting

Dynamic Light Scattering Malvern

Zetasizer Nano-S

Particle size distributions, diffusion coefficients, and molecular weight information

Surface Plasmon Resonance

BIACORE

3000

Kinetics of binding, binding heirarchies, concentration studies

Scintillation Counter PerkinElmer Tri-CArb 4810 TR

Quantitation of assays and substrates

Stopped Flow Spectrometer KinTek SF-300X Fast reaction kinetics
Multi-angle Light Scattering Instrument and Refractive Index Detector Wyatt Technology DAWN HELEOS II (MALS) / OptiLab rEX Absolute molecular weight, size and conformation of macromolecules in solution
Real-time Polymerase Chain Reaction Instrument Applied Biosystems StepOne Plus RT-PCR Quantitation of gene expression, assay validation
Preparative Ultracentrifuge Beckman XPN Pelleting of samples, zonal and continuous flow separation methods.
Nanodrop 1000 Thermo Scientific Nanodrop 1000 Measurement of DNA, RNA and protein concentration.
Microfluidizer Microfluidics Microfluidizer Cell disruption.
Freezer/Mill SPEX Freezer/MIll 6875A The Freezer/Mill is a cryogenic grinder to process samples in liquid nitrogen.
Emulsifier Avestin EmulsiFlex-C3 Cell disruption and sample homogenization.
Nanoparticle Tracking Analyzer Particle Metrix Zetaview Measurement of sizes and concentrations of nanoparticles in solution.
Thermocycler Tetrad MJ Research Tetrad MTC-225 Thermocylcler to perform Polymerase Chain Reactions using temperature gradients and up to 4 different programs.
BLI Octect K2 ForteBio Octect K2 Bio-Layer Interferometry (BLI) to measure binding interactions of small molecules, proteins, antibodies, and even cells.