Instrument

Make

Model

Year Purchased

Location

Major Applications

Fluorometer

Perkin Elmer

LS50B

2001

SI033

Structure, folding, binding thermodynamics and kinetics

Analytical Ultracentrifuge

Beckman Coulter

Optima XL-I

1998

SI033

Self-association (size, shape, and thermodynamics)

Isothermal Titration Calorimeter

Microcal

VP-ITC

2003

SI033

Thermodynamics of binding

Variable Mode Imaging System

Amersham Biosciences

Typhoon 9210

2003

SI033

Quantitation of gels, plates, autoradiograms, etc.

Circular Dichroism Spectrometer

Jasco

J-715

1999

A715

Structure and interactions

UV/Visible Spectrometer

Varian

Cary 100 Bio

2001

SI033

Thermodynamics of folding and kinetic assays, oligonucleotide melting

Dynamic Light Scattering

Malvern

Zetasizer Nano-S

2004

SI033

Particle size distributions, diffusion coefficients, and molecular weight information

Surface Plasmon Resonance

BIACORE

3000

2001

SI033

Kinetics of binding, binding heirarchies, concentration studies

Scintillation Counter

Packard

1600TR

1994

SI033

Quantitation of assays and substrates