A search of Medline at Indiana University, Bloomington, Indiana
Record 1 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sister and brother with Vici syndrome: agenesis of the corpus callosum, albinism, and recurrent infections.
AUTHOR: Chiyonobu,-Tomohiro; Yoshihara,-Takao; Fukushima,-Yoko; Yamamoto,-Yasutoshi; Tsunamoto,-Kentaro; Nishimura,-Yasutaka; Ishida,-Hiroyuki; Toda,-Tatsushi; Kasubuchi,-Yasuo
ADDRESS OF AUTHOR: Department of Pediatrics, Matsushita Memorial Hospital, Osaka, Japan. kidsaid@mhio.meli.co.jp
SOURCE: Am-J-Med-Genet. 2002 Apr 15; 109(1): 61-6
INTERNATIONAL STANDARD SERIAL NUMBER: 0148-7299
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: United-States
ABSTRACT: A sister and brother with Vici syndrome are described. They both had oculocutaneous albinism, agenesis of the corpus callosum, cataracts, and cardiomyopathy. They were born to healthy unrelated parents, and had postnatal growth retardation, profound developmental delay, hypotonia, and cataracts. The sister had recurrent infections, and died of progressive heart failure at age 19 months. The brother is alive at age six months with mild cardiomyopathy, and had a single episode of acute bronchitis at age three months. Review of the clinical manifestations of the sibs we described and six children reported in the literature indicates that Vici syndrome is a distinct clinical entity. Its main clinical manifestations include growth retardation, profound developmental delay, hypotonia, albinism, agenesis of the corpus callosum, cataracts, cardiomyopathy, and recurrent infections. The occurrence of the syndrome in three pairs of sibs of both sexes born to unaffected parents supports autosomal recessive inheritance. Copyright 2002 Wiley-Liss, Inc.
MAJOR MESH DESCRIPTORS: *Abnormalities,-Multiple-pathology; *Albinism-; *Corpus-Callosum-abnormalities; *Skin-Diseases,-Infectious-pathology
MINOR MESH DESCRIPTORS: Abnormalities,-Multiple-genetics; Family-Health; Fatal-Outcome; Infant-; Syndrome-
CHECKTAGS: Case-Report; Female; Human; Male
PUBLICATION TYPE: Journal-Article; Review; Review-of-Reported-Cases
SUBHEADINGS: genetics; pathology; abnormalities
SUBSET: Index-Medicus
UPDATE CODE: 20020619
ACCESSION NUMBER: 21929237
RECORD FEATURES: ABSTRACT (AB)
Record 2 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 3 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 4 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 5 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 6 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 7 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 8 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 9 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 10 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 11 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 12 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 13 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 14 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 15 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 16 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 17 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 18 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 19 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 20 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 21 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 22 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 23 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 24 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 25 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 26 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 27 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 28 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 29 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 30 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 31 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 32 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 33 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)
Record 34 of 34 in MEDLINE(R) on CD 2002/01-2002/06
TITLE: Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.
AUTHOR: Lessard,-Nadia; Lepore,-Franco; Villemagne,-Jean; Lassonde,-Maryse
ADDRESS OF AUTHOR: Hopital du Sacre-Coeur de Montreal, Canada.
SOURCE: Brain. 2002 May; 125(Pt 5): 1039-53
INTERNATIONAL STANDARD SERIAL NUMBER: 0006-8950
PUBLICATION YEAR: 2002
LANGUAGE: English
COUNTRY OF PUBLICATION: England
ABSTRACT: In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.
MAJOR MESH DESCRIPTORS: *Brain-physiology; *Corpus-Callosum-abnormalities; *Corpus-Callosum-surgery; *Sound-Localization-physiology
MINOR MESH DESCRIPTORS: Acoustic-Stimulation-methods; Acoustic-Stimulation-statistics-and-numerical-data; Adolescence-; Adult-; Analysis-of-Variance; Child-; Child,-Preschool; Corpus-Callosum-physiology; Neuronal-Plasticity-physiology
CHECKTAGS: Case-Report; Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't
PUBLICATION TYPE: Journal-Article
SUBHEADINGS: methods; statistics-and-numerical-data; physiology; abnormalities; surgery
SUBSET: Abridged-Index-Medicus; Index-Medicus
UPDATE CODE: 20020617
ACCESSION NUMBER: 21958709
RECORD FEATURES: ABSTRACT (AB)