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AVM (arteriovenus malformation),

the recent (September, 2001) literature

web contact: pietsch@indiana.edu
A literature search at Indiana University, Bloomington, Indiana
The following MEDLINE items were compiled by SilverPlatter and are presented with their generous co-operation and permission.

Record 1 of 34 in MEDLINE(R) on CD 2001/07

TITLE: CT and DSA appearances of ruptured congenital AVM.

AUTHOR: Jackson,-J; Thompson,-W; Graham,-A

SOURCE: Br-J-Radiol. 2001 Jun; 74(882): 565-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0007-1285

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: England

MAJOR MESH DESCRIPTORS: *Aorta,-Thoracic-abnormalities; *Arteriovenous-Malformations-diagnosis

MINOR MESH DESCRIPTORS: Adult-; Angiography,-Digital-Subtraction; Diagnosis,-Differential; Rupture,-Spontaneous; Tomography,-X-Ray-Computed

CHECKTAGS: Case-Report; Human

PUBLICATION TYPE: Letter

SUBHEADINGS: abnormalities; diagnosis

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21352626

Record 2 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Concurrent spinal dural and intradural arteriovenous fistulas. Case report.

AUTHOR: Dam-Hieu,-P; Mineo,-J-F; Bostan,-A; Nonent,-M; Besson,-G

ADDRESS OF AUTHOR: Department of Neurosurgery and Neuroradiology, Cavale-Blanche Hospital, University of Bretagne Occidentale, Brest, France. phongdamhieu@hotmail.com

SOURCE: J-Neurosurg. 2001 Jul; 95(1 Suppl): 96-9

INTERNATIONAL STANDARD SERIAL NUMBER: 0022-3085

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: Among spinal arteriovenous malformations (AVMs), dural arteriovenous fistulas (DAVFs) should be distinguished from intradural AVMs. The authors report the unusual and well-documented case of a 49-year-old man who suffered from a rapidly progressive myelopathy. Two concurrent spinal AVMs (one DAVF and one intradural direct AVF [Anson-Spetzler Type IV-B AVM]) were found located in the midthoracic region and in the conus medullaris, respectively. Both AVMs were successfully treated by surgery. To the authors' knowledge, the association of these two pathological entities has not been previously described. Clinically, if the patient fails to improve or deteriorates after the treatment of a spinal AVM, the presence of another AVM should be investigated by repeated angiography, especially if a complete spinal angiography study was not initially performed.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Fistula-surgery; *Arteriovenous-Malformations-surgery; *Dura-Mater-blood-supply; *Spinal-Cord-blood-supply

MINOR MESH DESCRIPTORS: Angiography-; Arteriovenous-Fistula-diagnosis; Arteriovenous-Malformations-diagnosis; Dura-Mater-surgery; Magnetic-Resonance-Imaging; Middle-Age; Reoperation-

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnosis; surgery; blood-supply

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21345973

RECORD FEATURES: ABSTRACT (AB)

Record 3 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Morbidite et mortalite du traitement chirurgical des malformations arterio-veineuses cerebrales. Donnees actuelles et analyse de la litterature recente.

[Postoperative morbidity and mortality after microsurgical exclusion of cerebral arteriovenous malformations. Current data and analysis of recent literature]

AUTHOR: Castel,-J-P; Kantor,-G

ADDRESS OF AUTHOR: Clinique Universitaire de Neurochirurgie, Hopital Pellegrin, 33076 Bordeaux Cedex.

SOURCE: Neurochirurgie. 2001 May; 47(2-3 Pt 2): 369-83

INTERNATIONAL STANDARD SERIAL NUMBER: 0028-3770

PUBLICATION YEAR: 2001

LANGUAGE: French; Non-English

COUNTRY OF PUBLICATION: France

ABSTRACT: BACKGROUND AND PURPOSE: Microsurgical exclusion of a cerebral arteriovenous malformation (AVM) can compare favorably with radiosurgery. We sought to assess its rate of morbidity-mortality as it is presently reported in the literature, and to discuss some of its current and worthwhile indications. METHODS: Through Medline and additional searches by hand, we retrieved studies reporting the clinical and angiographic results after microsurgical excision of an AVM published between january 1990 and december 2000. RESULTS: a) Postoperative mortality was 3.3% (68/2 452 patients from 25 studies). Permanent postoperative morbidity was 8.6%. Morbidity was never absent varying from 1.5% to 18,7%. The morbidity-mortality rate increased with an increasing Spetzler-Martin's grade, and was related to the location of the AVM. A 4.6% morbidity (from 1.5% to 9.7%) and a zero mortality were reported after microsurgical removal of small lesions of less than 3 cm in diameter. b) Postoperative angiography confirmed a total excision of the AVM in 97% of the cases (1 050/1 076 patients over 11 series), varying from 91% to 100%. c) Permanent morbidity related to pre-surgical embolization varied from 4% to 8.9%. Results from multiple or combined treatment including microsurgery could not be summed up. CONCLUSIONS: A complete and definitive microsurgical excision of an AVM can be achieved with a high success rate and a low morbidity-mortality rate, according to sound indications and to the neurosurgeon's personal experience. The choice for a best treatment of an AVM is no longer limited to microsurgery; it is a team decision where the neurosurgeon plays a determining role.

MAJOR MESH DESCRIPTORS: *Brain-Damage,-Chronic-etiology; *Intracranial-Arteriovenous-Malformations-surgery; *Microsurgery-adverse-effects; *Postoperative-Complications-etiology; *Radiosurgery-adverse-effects

MINOR MESH DESCRIPTORS: Adult-; Aged-; Brain-Damage,-Chronic-epidemiology; Case-Management; Cerebral-Angiography; Cerebral-Hemorrhage-etiology; Cerebral-Hemorrhage-surgery; Child-; Combined-Modality-Therapy; Comorbidity-; Cost-Benefit-Analysis; Embolization,-Therapeutic; Emergencies-; France-epidemiology; Hematoma-etiology; Hematoma-surgery; Intracranial-Aneurysm-epidemiology; Intracranial-Aneurysm-etiology; Intracranial-Aneurysm-surgery; Intracranial-Arteriovenous-Malformations-complications; Intracranial-Arteriovenous-Malformations-epidemiology; Intracranial-Arteriovenous-Malformations-radiography; Intracranial-Arteriovenous-Malformations-therapy; Microsurgery-economics; Microsurgery-methods; Microsurgery-mortality; Middle-Age; Postoperative-Complications-epidemiology; Postoperative-Complications-mortality; Prospective-Studies; Radiosurgery-economics; Radiosurgery-mortality; Retrospective-Studies; Severity-of-Illness-Index; Treatment-Outcome

CHECKTAGS: Comparative-Study; English-Abstract; Female; Human; Male

PUBLICATION TYPE: Journal-Article; Review; Review,-Tutorial

SUBHEADINGS: epidemiology; etiology; surgery; complications; radiography; therapy; adverse-effects; economics; methods; mortality

SUBSET: Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21297853

RECORD FEATURES: ABSTRACT (AB)

Record 4 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Incidentally discovered giant renal arteriovenous malformation.

AUTHOR: Asakuma,-J; Miyajima,-A; Sawazaki,-H; Mizuguchi,-Y; Seguchi,-K; Ito,-K; Asano,-T; Ogata,-S; Tamai,-S; Hayakawa,-M

ADDRESS OF AUTHOR: Department of Urology, National Defense Medical College, Tokorozawa, Saitama, Japan. cal80240@pop07.odn.ne.jp

SOURCE: Int-J-Urol. 2001 Jun; 8(6): 322-5

INTERNATIONAL STANDARD SERIAL NUMBER: 0919-8172

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: Australia

ABSTRACT: A case is presented of giant renal arteriovenous malformation (AVM). A 61-year-old woman was admitted to the National Defense Medical College Hospital for further evaluation of a renal cyst. Doppler ultrasonography and magnetic resonance imaging revealed a giant renal AVM, although the patient had no history nor clinical sign suggesting an AVM. Under the diagnosis of a right renal AVM, the patient underwent AVM resection.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-pathology; *Arteriovenous-Malformations-ultrasonography; *Kidney,-Cystic-ultrasonography

MINOR MESH DESCRIPTORS: Arteriovenous-Malformations-surgery; Kidney-blood-supply; Magnetic-Resonance-Angiography; Middle-Age; Renal-Veins-pathology; Renal-Veins-surgery; Renal-Veins-ultrasonography; Ultrasonography,-Doppler; Vena-Cava,-Inferior-pathology; Vena-Cava,-Inferior-surgery; Vena-Cava,-Inferior-ultrasonography

CHECKTAGS: Case-Report; Female; Human

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: pathology; surgery; ultrasonography; blood-supply

SUBSET: Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21286269

RECORD FEATURES: ABSTRACT (AB)

Record 5 of 34 in MEDLINE(R) on CD 2001/07

TITLE: What factors are related to impairment of cerebrovascular reserve before and after arteriovenous malformation resection? A cerebral blood flow study using xenon-enhanced computed tomography.

AUTHOR: Van-Roost,-D; Schramm,-J

ADDRESS OF AUTHOR: Department of Neurosurgery, University of Bonn, Germany. DVRoost@meb.uni-bonn.de

SOURCE: Neurosurgery. 2001 Apr; 48(4): 709-16; discussion 716-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0148-396X

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: OBJECTIVE: To examine the incidence and possible determinants of impaired vascular reserve in arteriovenous malformation (AVM)-affected brain, before and after surgery. METHODS: In a prospective study of 30 patients, the regional cerebrovascular reserve capacity (rCRC) and the vasodilated regional cerebral blood flow (rCBF) were assessed during an acetazolamide challenge, using xenon-enhanced computed tomography, before and after complete AVM resection. Single brain slices at the level of the basal ganglia were examined, and scanning through the AVMs was avoided. Five regions of interest in the AVM-bearing hemisphere were compared with their counterparts in the unaffected hemisphere. Vasodilated rCBF reductions of at least 20% in one or more regions of interest and rCRC values of less than 10 ml/100 g/min were considered to be significant. RESULTS: Ipsilateral vasodilated rCBF was significantly reduced in 17 patients before surgery and 15 patients after surgery. Ipsilateral rCRC was impaired in 14 patients before surgery and 12 patients after surgery. Large AVM size, venous congestion, and AVM-related vascular territories were correlated with impaired vascular reserve in AVM-nonadjacent brain tissue before surgery. Similar correlations were observed after surgery, except that not AVM size but a large number of AVM-supplying vascular territories was correlated. Moreover, the smallest AVMs and those supplied by a single vascular territory, as well as hemorrhage and nonhemorrhagic neurological deficits as presenting symptoms, were correlated with reduced ipsilateral vasodilated rCBF before surgery. Among patients with AVMs and nonhemorrhagic epilepsy, a trend of impaired cerebrovascular reserve was observed. In the only case of postresectional "breakthrough," the preoperative rCRC was not impaired but abnormally high. CONCLUSION: Among the determinants of impaired cerebrovascular reserve, AVM size is already a constituent of current grading scales and decision-making paradigms, whereas factors such as venous congestion have been less closely considered or less obvious but may deserve increased attention in the future. Nonhemorrhagic epilepsy in patients with AVMs may constitute the clinical equivalent of chronic cerebral ischemia in a murine model. Postresectional breakthrough may be partly attributable to individual predisposition to excessive vasoreactivity in the whole brain.

MAJOR MESH DESCRIPTORS: *Brain-blood-supply; *Brain-Ischemia-radiography; *Contrast-Media; *Intracranial-Arteriovenous-Malformations-surgery; *Postoperative-Complications-radiography; *Tomography,-X-Ray-Computed; *Xenon-Isotopes-diagnostic-use

MINOR MESH DESCRIPTORS: Acetazolamide-diagnostic-use; Adolescence-; Adult-; Aged-; Basal-Ganglia-blood-supply; Brain-radiography; Brain-Ischemia-physiopathology; Dominance,-Cerebral-physiology; Intracranial-Arteriovenous-Malformations-physiopathology; Intracranial-Arteriovenous-Malformations-radiography; Middle-Age; Postoperative-Complications-physiopathology; Regional-Blood-Flow-physiology; Risk-Factors; Vasodilation-physiology

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnostic-use; blood-supply; radiography; physiopathology; physiology; surgery

CAS REGISTRY NUMBER OR EC NUMBER: 0; 0; 59-66-5

NAME OF SUBSTANCE: Contrast-Media; Xenon-Isotopes; Acetazolamide

SUBSET: Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21219772

RECORD FEATURES: ABSTRACT (AB)

Record 6 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Determination of blood flow velocity and transit time in cerebral arteriovenous malformation using microdroplet angiography.

AUTHOR: Divani,-A-A; Lieber,-B-B; Wakhloo,-A-K; Gounis,-M-J; Hopkins,-L-N

ADDRESS OF AUTHOR: Department of Mechanical and Aerospace Engineering, State University of New York at Buffalo, USA.

SOURCE: Ann-Biomed-Eng. 2001 Feb; 29(2): 135-44

INTERNATIONAL STANDARD SERIAL NUMBER: 0090-6964

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: Advancement in imaging and biomedical technology has improved the use of catheter-based transarterial embolization (occlusive therapy) of cerebral arteriovenous malformations (AVMs). Among a variety of embolic agents, liquid adhesives (acrylates) have proven to be more successful in permanent obliteration of AVMs. The use of liquid adhesives requires the experience and skill of the operator. However, acquiring accurate information on blood flow and transit times through the AVM prior to embolization can optimize the treatment. In addition, knowledge of the polymerization time and behavior of the acrylate enables a complete and safe occlusion of the arteriovenous transition within the AVM nidus. Standard commercially available iodine-based contrast agents seem to be insufficient to determine AVM transit times from angiograms. For a more accurate assessment of AVM transit times, the use of a nonsoluble contrast agent (Ethiodol) and a high-speed digital subtraction angiography (DSA) is suggested. Small amounts (<20 microl) of Ethiodol were infused to create microdroplets and traced using DSA at 15 fps. Transit time, defined as the time interval required for a droplet to reach the venous part of the AVM after being flushed from the tip of the catheter, could be accurately calculated. Postprocessing was used to calculate trajectories and velocities of microdroplets.

MAJOR MESH DESCRIPTORS: *Angiography,-Digital-Subtraction-methods; *Cerebral-Angiography-methods; *Intracranial-Arteriovenous-Malformations-physiopathology; *Intracranial-Arteriovenous-Malformations-radiography

MINOR MESH DESCRIPTORS: Biomedical-Engineering; Blood-Flow-Velocity; Cerebrovascular-Circulation; Contrast-Media; Embolization,-Therapeutic; Ethiodized-Oil; Intracranial-Arteriovenous-Malformations-therapy; Time-Factors

CHECKTAGS: Human

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: methods; physiopathology; radiography; therapy

CAS REGISTRY NUMBER OR EC NUMBER: 0; 8008-53-5

NAME OF SUBSTANCE: Contrast-Media; Ethiodized-Oil

SUBSET: Index-Medicus

UPDATE CODE: 20010802

ACCESSION NUMBER: 21177914

RECORD FEATURES: ABSTRACT (AB)

Record 7 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Is stagnating flow in former feeding arteries an indication of cerebral hypoperfusion after resection of arteriovenous malformations?

AUTHOR: Meyer,-B; Urbach,-H; Schaller,-C; Schramm,-J

ADDRESS OF AUTHOR: Department of Neurosurgery, University of Bonn, Germany. bmey@ukb.uni-bonn.de

SOURCE: J-Neurosurg. 2001 Jul; 95(1): 36-43

INTERNATIONAL STANDARD SERIAL NUMBER: 0022-3085

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: OBJECT: The authors' goal in this study was to challenge the proposed mechanism of the occlusive hyperemia theory, in which it is asserted that stagnating flow in the former feeding arteries of cerebral arteriovenous malformations (AVMs) leads to parenchymal hypoperfusion or ischemia, from which postoperative edema and hemorrhage originate. METHODS: Cortical oxygen saturation (SaO2) was measured in 52 patients by using microspectrophotometry in areas adjacent to AVMs before and after resection. The appearance of the former feeding arteries was categorized as normal (Group A); moderately stagnating (Group B); and excessively stagnating (Group C) on postoperative angiographic fast-film series. Patients and SaO2 values were pooled accordingly and compared using analysis of variance and Duncan tests (p < 0.05). Angiographic stagnation times in former feeding arteries were correlated in a linear regression/correlation analysis with SaO2 data (p < 0.05). All values are given as the mean +/- standard deviation. The average median postoperative SaO2 in Group C (15 patients) was significantly higher than in Groups B (17 patients) and A (20 patients) (Group C, 75.2 +/- 8.5; Group B, 67.5 +/- 10.8; Group A, 67.1 +/- 12 %SaO2), as was the average postoperative increase in SaO2 (Group C. 25.9 +/- 14.9; Group B, 14.6 +/- 14; Group A, 11.1 +/- 14 %SaO2). Angiographically confirmed stagnation times were also significantly longer in Group C than in Group B (Group C, 5.6 +/- 2.5; Group B, 1.3 +/- 0.6 seconds). A significant correlation/regression analysis showed a clear trend toward higher postoperative SaO2 levels with increasing stagnation time. CONCLUSIONS: Stagnating flow in former feeding arteries does not cause cortical ischemia, but its presence on angiographic studies is usually indicative of hyperperfusion in the surrounding brain tissue after AVM resection. In the context of the pathophysiology of AVMs extrapolations made from angiographically visible shunt flow to blood flow in the surrounding brain tissue must be regarded with caution.

COMMENTS: Comment In: J Neurosurg. 2001 Jul;95(1):165-7 21345954

MAJOR MESH DESCRIPTORS: *Brain-blood-supply; *Brain-Ischemia-diagnosis; *Intracranial-Arteriovenous-Malformations-surgery; *Oxygen-Consumption-physiology; *Postoperative-Complications-diagnosis

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Aged-; Brain-Edema-diagnosis; Brain-Edema-physiopathology; Brain-Ischemia-physiopathology; Cerebral-Hemorrhage-diagnosis; Cerebral-Hemorrhage-physiopathology; Child-; Child,-Preschool; Collateral-Circulation-physiology; Hyperemia-diagnosis; Hyperemia-physiopathology; Intracranial-Arteriovenous-Malformations-physiopathology; Microspectrophotometry-; Microsurgery-; Middle-Age; Postoperative-Complications-physiopathology

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: blood-supply; diagnosis; physiopathology; physiology; surgery

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010726

ACCESSION NUMBER: 21345932

RECORD FEATURES: ABSTRACT (AB)

Record 8 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Paraplegie et malformation arterioveineuse medullaire. Place de la chirurgie, de la corticotherapie et de l'embolisation.

[Paraplegia and medullary arteriovenous malformation. Role of surgery, corticosteroids and embolization]

AUTHOR: Vodoff,-M-V; Gilbert,-B; Le-Breton,-F; Rodesch,-G; Laroche,-C; Lagarrigue,-J-F; de-Lumley,-L; Lasjaunias,-P

ADDRESS OF AUTHOR: Service de pediatrie 1, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges, France.

SOURCE: Arch-Pediatr. 2001 Jun; 8(6): 608-10

INTERNATIONAL STANDARD SERIAL NUMBER: 0929-693X

PUBLICATION YEAR: 2001

LANGUAGE: French; Non-English

COUNTRY OF PUBLICATION: France

ABSTRACT: CASE REPORT: We report the case of a nine-year-old child with a cervical medullary arteriovenous malformation (AVM), revealed by total paraplegia, whose regression started during steroid therapy, before embolization. CONCLUSION: The frequency of AVM's spontaneous favorable outcome is unknown but should not be underestimated. It might be improved by steroids.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-complications; *Paraplegia-etiology; *Spinal-Cord-blood-supply

MINOR MESH DESCRIPTORS: Adrenal-Cortex-Hormones-therapeutic-use; Arteriovenous-Malformations-pathology; Arteriovenous-Malformations-surgery; Child-; Embolization,-Therapeutic; Magnetic-Resonance-Imaging; Spinal-Cord-pathology; Treatment-Outcome

CHECKTAGS: Case-Report; English-Abstract; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: therapeutic-use; complications; pathology; surgery; etiology; blood-supply

CAS REGISTRY NUMBER OR EC NUMBER: 0

NAME OF SUBSTANCE: Adrenal-Cortex-Hormones

SUBSET: Index-Medicus

UPDATE CODE: 20010726

ACCESSION NUMBER: 21339853

RECORD FEATURES: ABSTRACT (AB)

Record 9 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Intracranial arteriovenous malformations: real-time auto-triggered elliptic centric-ordered 3D gadolinium-enhanced MR angiography--initial assessment.

AUTHOR: Farb,-R-I; McGregor,-C; Kim,-J-K; Laliberte,-M; Derbyshire,-J-A; Willinsky,-R-A; Cooper,-P-W; Westman,-D-G; Cheung,-G; Schwartz,-M-L; Stainsby,-J-A; Wright,-G-A

ADDRESS OF AUTHOR: Department of Medical Imaging, Division of Neuroradiology, University of Toronto, University Health Network, Toronto Western Hospital, Fell Pavilion 3-404, 300 Bathurst St, Toronto, Ontario, Canada M5T 2S8. richard.farb@utoronto.ca

SOURCE: Radiology. 2001 Jul; 220(1): 244-51

INTERNATIONAL STANDARD SERIAL NUMBER: 0033-8419

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: Auto-triggered elliptic centric-ordered three-dimensional (3D) gadolinium-enhanced magnetic resonance (MR) angiography was compared with 3D multiple overlapping thin-slab acquisition time-of-flight (TOF) MR angiography in the evaluation of intracranial arteriovenous malformations (AVMs) in 10 patients. Intraarterial digital subtraction angiography (DSA) was the reference standard. Gadolinium-enhanced MR angiograms were found to be equivalent to DSA images in AVM component depiction in 70%--90% of cases and were consistently superior to TOF MR angiograms.

MAJOR MESH DESCRIPTORS: *Contrast-Media; *Gadolinium-diagnostic-use; *Image-Enhancement-methods; *Intracranial-Arteriovenous-Malformations-diagnosis; *Magnetic-Resonance-Angiography-methods

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Aged-; Cerebral-Angiography-methods; Middle-Age; Prospective-Studies; Sensitivity-and-Specificity

CHECKTAGS: Comparative-Study; Female; Human; Male; Support,-Non-U.S.-Gov't

PUBLICATION TYPE: Clinical-Trial; Journal-Article

SUBHEADINGS: methods; diagnostic-use; diagnosis

CAS REGISTRY NUMBER OR EC NUMBER: 0; 7440-54-2

NAME OF SUBSTANCE: Contrast-Media; Gadolinium

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010719

ACCESSION NUMBER: 21319557

RECORD FEATURES: ABSTRACT (AB)

Record 10 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Congenital arteriovenous malformation of the pancreas: its diagnostic features on images.

AUTHOR: Koito,-K; Namieno,-T; Nagakawa,-T; Ichimura,-T; Hirokawa,-N; Mukaiya,-M; Hirata,-K; Hareyama,-M

ADDRESS OF AUTHOR: Department of Radiology, Sapporo Medical University, Japan. koito@sapmed.ac.jp

SOURCE: Pancreas. 2001 Apr; 22(3): 267-73

INTERNATIONAL STANDARD SERIAL NUMBER: 0885-3177

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: To analyze diagnostic features on images of congenital arteriovenous malformation (AVM) of the pancreas, we analyzed the diagnostic findings in six patients with the disease, using gray-scale ultrasonography (US), color Doppler US, computed tomography, and angiography and analyzed previously reported cases. AVM characteristic findings on images were multiple, small hypoechoic nodules on US, mosaic appearance of the lesion and pulsatile wave form in the portal vein on color Doppler US, conglomerated small nodular enhancement of the lesion and early appearance of the portal vein on CT, and a racemose network and early appearance of the portal vein on angiography. Five of the six patients underwent surgery, and all resected specimens were histologically found to be AVMs of the pancreas; however, one with developed portal hypertension at surgery died of repeated bleeding from esophageal varices. From analysis of total of 35 cases including our six cases, a mosaic appearance of the lesion was found in 100% and a pulsatile wave form in the portal vein in 77.8% on color Doppler US. Color Doppler US is noninvasive and useful for detecting congenital AVM of the pancreas at an early stage, preventing the portal hypertension causing esophageal varices and their rupture.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-diagnosis; *Pancreas-blood-supply

MINOR MESH DESCRIPTORS: Adult-; Aged-; Angiography-; Arteriovenous-Malformations-surgery; Common-Bile-Duct-pathology; Esophageal-and-Gastric-Varices-complications; Fibrosis-; Middle-Age; Pancreatic-Ducts-pathology; Pancreaticoduodenectomy-; Tomography,-X-Ray-Computed; Ultrasonography-; Ultrasonography,-Doppler,-Color

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnosis; surgery; pathology; complications; blood-supply

SUBSET: Index-Medicus

UPDATE CODE: 20010719

ACCESSION NUMBER: 21187271

RECORD FEATURES: ABSTRACT (AB)

Record 11 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Aplicacoes pre-cirurgicas do mapeamento cortical por Ressonancia Magnetica Funcional.

[Preoperative applications of cortical mapping with functional magnetic resonance]

AUTHOR: Cravo,-I; Palma,-T; Conceicao,-C; Evangelista,-P

ADDRESS OF AUTHOR: Servico de Neurorradiologia, Hospital de Egas Moniz, Centro de Ressonancia Magnetica de Caselas, Lisboa.

SOURCE: Acta-Med-Port. 2001 Jan-Feb; 14(1): 21-5

INTERNATIONAL STANDARD SERIAL NUMBER: 0870-399X

PUBLICATION YEAR: 2001

LANGUAGE: Portuguese; Non-English

COUNTRY OF PUBLICATION: Portugal

ABSTRACT: The authors describe a clinical experience in cortical brain mapping by Functional Magnetic Resonance Imaging (FMRI) with a 1.0 T MR scanner with BOLD technique and echo-planar imaging (EPI). A brief review is made of the theoretical basis of the BOLD technique and of the different functional tasks used. The main clinical applications of FMRI cortical mapping regarding the sensorimotor cortex of the hand and of language are mentioned. The experiment involves 29 patients, 16 with gliomas (G), 7 with mesial temporal sclerosis (MT S) and 6 with arteriovenous malformations (AVM) The most frequent clinical applications were the determination of the topographic relationship of the cerebral lesions with these eloquent cortices as well as the presurgical lateralization of language in medically intractable epileptic patients. The results are discussed in order to assess the FMRI cortical mapping role as a noninvasive method for presurgical planning, regarding the evaluation of the potential neurosurgical risks and the identification of viable cortex regions displaced or reorganized as a consequence of disease. Additionally, FMRI cortical mapping can also assess the atypical speech representations and the language lateralization of the patients.

MAJOR MESH DESCRIPTORS: *Brain-Diseases-pathology; *Brain-Diseases-surgery; *Brain-Mapping-methods; *Cerebral-Cortex-pathology; *Intracranial-Arteriovenous-Malformations-pathology; *Intracranial-Arteriovenous-Malformations-surgery; *Magnetic-Resonance-Imaging; *Preoperative-Care

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Middle-Age

CHECKTAGS: English-Abstract; Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: pathology; surgery; methods

SUBSET: Index-Medicus

UPDATE CODE: 20010712

ACCESSION NUMBER: 21220401

RECORD FEATURES: ABSTRACT (AB)

Record 12 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Hochaufgeloste MR-Venographie zerebraler arteriovenoser Malformationen.

[High resolution MR-venography of cerebral arteriovenous malformations]

AUTHOR: Essig,-M; Reichenbach,-J-R; Schad,-L; Debus,-J; Kaiser,-W-A

ADDRESS OF AUTHOR: Forschungsschwerpunkt Radiologische Diagnostik und Therapie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg. M.Essig@dkfz-heidelberg.de

SOURCE: Radiologe. 2001 Mar; 41(3): 288-95

INTERNATIONAL STANDARD SERIAL NUMBER: 0033-832X

PUBLICATION YEAR: 2001

LANGUAGE: German; Non-English

COUNTRY OF PUBLICATION: Germany

ABSTRACT: PURPOSE: The purpose of this study was to evaluate the diagnostic potential of a high resolution MR venography technique in patients with cerebral arteriovenous malformations (AVM). A high-resolution 3D gradient echo sequence was used with a long echo time TE to obtain venous information down to sub-pixel sized vessel diameters of several hundred microns. The method is based on the paramagnetic property of deoxyhemoglobin and the resulting developing phase difference between veins and brain parenchyma at long echo times which leads to signal cancellation. The reconstructed venograms were compared with TOF-MR angiography using qualitative and quantitative criteria with the conventional DSA serving as the reference gold standard. METHODS: In 17 patients with angiographically proven cerebral AVM the method indicates its potential in clinical applications. Venography was able to detect all AVM whereas TOF-MRA failed in three patients. In the delineation of venous drainage patterns MR venography was superior to TOF-MRA, however, as expected the method detected only about half of the main feeding arteries. Due to susceptibility artifacts at air/tissue boundaries or interference with paramagnetic hemosiderin, MR venography was limited with respect to the delineation of the exact nidus sizes and shapes in ten patients with AVM located close to the skull base or in patients having suffered from previous bleeding. RESULTS: Although the visualization of draining veins represents an important prerequisite in the surgical and radiosurgical treatment planning of cerebral AVM, there exist limitations of the technique in regions where strong induced static field inhomogeneities are present. CONCLUSIONS: Due to its high sensitivity the method may be of special importance in the early detection and assessment of small AVM which are difficult to diagnose with other MR methods.

MAJOR MESH DESCRIPTORS: *Image-Enhancement; *Imaging,-Three-Dimensional; *Intracranial-Arteriovenous-Malformations-diagnosis; *Magnetic-Resonance-Angiography; *Phlebography-

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Artifacts-; Cerebral-Veins-pathology; Child-; Middle-Age; Predictive-Value-of-Tests; Skull-Base-blood-supply

CHECKTAGS: English-Abstract; Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: pathology; diagnosis; blood-supply

SUBSET: Index-Medicus

UPDATE CODE: 20010705

ACCESSION NUMBER: 21220511

RECORD FEATURES: ABSTRACT (AB)

Record 13 of 34 in MEDLINE(R) on CD 2001/07

TITLE: Europium fluorescence to visualize N-butyl 2-cyanoacrylate in embolized vessels of an arteriovenous malformation swine model.

AUTHOR: Calvo,-W-J; Lieber,-B-B; Hopkins,-L-N; Wakhloo,-A-K

ADDRESS OF AUTHOR: Toshiba Stroke Research Center, NY, USA.

SOURCE: AJNR-Am-J-Neuroradiol. 2001 Apr; 22(4): 691-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0195-6108

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: BACKGROUND AND PURPOSE: Standard tissue staining using the lipid dye Oil-Red-O has been previously applied to stain vessel specimens, which were embolized with a mixture of n-butyl 2-cyanoacrylate (NBCA) and oil (Lipiodol). That technique, however, results in nonspecific and nonquantitative staining that does not provide the necessary differentiation between NBCA and Lipiodol. We present an innovative staining procedure that quantifies NBCA within treated tissues. METHODS: An arteriovenous malformation (AVM) model in swine was used to evaluate the polymerization characteristics of various ratios of Lipiodol/NBCA/glacial acetic acid (GAA) mixtures. To determine the depth of NBCA penetration within the AVM model and to characterize the polymerization patterns of various mixtures within the vessel, histologic cross- and longitudinal sections were prepared for microscopy. These paraffin-embedded tissue sections were stained with a europium aryl-beta-diketone complex (TEC) to improve differentiation between NBCA and Lipiodol. Quantification of NBCA and Lipiodol within the lumen of rete cross-sections was accomplished using image analysis software to determine percent luminal area occluded by embolization. RESULTS: Upon application of TEC, intense europium fluorescence was seen when the tissue samples were excited by low-power UV light (excitation at 365 nm; emission at 614 nm). The area of europium intensity within the lumen corresponded to NBCA concentration, and addition of GAA aided the NBCA distribution throughout the lumen without affecting fluorescence intensity. It was seen that NBCA could be easily differentiated from Lipiodol and that quantification could be readily performed on these sections because of the improved differentiation. For the case of a 50:50 (vol. %) mixture with an added 20 microL of GAA, luminal area distribution of Lipiodol, NBCA, and blood products was 42.6 +/- 3.5%, 33.8 +/- 5.7%, and 23.7 +/-2.7%, respectively. CONCLUSION: The rare earth metal europium, when added as a fluorescent chelate compound to histologic tissue sections, allowed for differentiation between NBCA and Lipiodol with good detail. These results have facilitated further characterization of NBCA polymerization for the use of AVM embolization.

MAJOR MESH DESCRIPTORS: *Embolization,-Therapeutic; *Enbucrilate-pharmacology; *Europium-; *Intracranial-Arteriovenous-Malformations-therapy; *Microscopy,-Fluorescence

MINOR MESH DESCRIPTORS: Cerebral-Arteries-pathology; Cerebral-Veins-pathology; Disease-Models,-Animal; Intracranial-Arteriovenous-Malformations-pathology; Swine-

CHECKTAGS: Animal; Support,-Non-U.S.-Gov't; Support,-U.S.-Gov't,-P.H.S.

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: pathology; pharmacology; therapy

CAS REGISTRY NUMBER OR EC NUMBER: 6606-65-1; 7440-53-1

NAME OF SUBSTANCE: Enbucrilate; Europium

CONTRACT OR GRANT NUMBERS: HL0776509HLNHLBI

SUBSET: Index-Medicus

UPDATE CODE: 20010705

ACCESSION NUMBER: 21185652

RECORD FEATURES: ABSTRACT (AB)

Record 14 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Association of cerebral arteriovenous malformation with cerebral arterial fenestration.

AUTHOR: Uchino,-A; Kato,-A; Abe,-M; Kudo,-S

ADDRESS OF AUTHOR: Department of Radiology, Saga Medical School, Japan. uchino@post.saga-med.ac.jp

SOURCE: Eur-Radiol. 2001; 11(3): 493-6

INTERNATIONAL STANDARD SERIAL NUMBER: 0938-7994

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: Germany

ABSTRACT: Cerebral arteriovenous malformations (AVMs) are rarely associated with other vascular lesions. Our goal was to examine the incidence of the coexistence of cerebral AVMs and cerebral arterial fenestrations. During the past 18 years, 51 patients with a cerebral AVM were examined with selective cerebral angiography in our institution. We retrospectively reviewed these cerebral angiographies and noted associated cerebral arterial fenestrations. We found five fenestrations distributed among 3 patients. In each patient one fenestration was located in the vertebral artery (VA). In 1 patient there were additional basilar and left middle cerebral artery fenestrations. Vertebral artery angiography was performed in 43 of the 51 patients; thus, the frequency of coexistence of AVM and VA fenestration was 7% (3 of 43). Although the clinical significance may not be great, we found a noteworthy incidence of associated VA fenestrations in AVM cases.

MAJOR MESH DESCRIPTORS: *Cerebral-Angiography; *Intracranial-Arteriovenous-Malformations-radiography; *Vertebral-Artery-abnormalities

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Aged-; Angiography,-Digital-Subtraction; Basilar-Artery-abnormalities; Basilar-Artery-radiography; Child-; Child,-Preschool; Middle-Age; Middle-Cerebral-Artery-abnormalities; Middle-Cerebral-Artery-radiography; Subarachnoid-Hemorrhage-radiography; Vertebral-Artery-radiography

CHECKTAGS: Case-Report; Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: abnormalities; radiography

SUBSET: Index-Medicus

UPDATE CODE: 20010628

ACCESSION NUMBER: 21182484

RECORD FEATURES: ABSTRACT (AB)

Record 15 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Pulmonary arteriovenous malformation: Characterization with time-resolved ultrafast 3D MR angiography.

AUTHOR: Goyen,-M; Ruehm,-S-G; Jagenburg,-A; Barkhausen,-J; Kroger,-K; Debatin,-J-F

ADDRESS OF AUTHOR: Department of Diagnostic Radiology, University Hospital, Essen, Germany. mathias.goyen@uni-essen.de

SOURCE: J-Magn-Reson-Imaging. 2001 Mar; 13(3): 458-60

INTERNATIONAL STANDARD SERIAL NUMBER: 1053-1807

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: To avoid potentially deadly consequences from paradoxical emboli, early detection and accurate characterization of pulmonary arteriovenous malformations (AVMs) is highly desirable. We report on a patient with a suspected pulmonary AVM who underwent ultrafast time-resolved 3D MR angiography of the pulmonary arteries. The case documents the suitability of the MRA technique as a noninvasive alternative to computed tomographic angiography and digital subtraction angiography for accurate pre-therapeutic characterization of pulmonary AVMs.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-diagnosis; *Image-Enhancement; *Imaging,-Three-Dimensional; *Lung-blood-supply; *Magnetic-Resonance-Angiography

MINOR MESH DESCRIPTORS: Contrast-Media; Gadolinium-DTPA-diagnostic-use; Image-Processing,-Computer-Assisted; Middle-Age; Pulmonary-Artery-abnormalities; Pulmonary-Artery-pathology

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnosis; diagnostic-use; blood-supply; abnormalities; pathology

CAS REGISTRY NUMBER OR EC NUMBER: 0; 80529-93-7

NAME OF SUBSTANCE: Contrast-Media; Gadolinium-DTPA

SUBSET: Index-Medicus

UPDATE CODE: 20010628

ACCESSION NUMBER: 21134909

RECORD FEATURES: ABSTRACT (AB)

Record 16 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: [A case of cerebral arteriovenous malformation complicated with intracerebral hemorrhage after endovascular embolization]

AUTHOR: Hayashi,-K; Takahata,-H; Kitagawa,-N; Morikawa,-M; Ochi,-M; Hayashi,-T; Kazekawa,-K; Kaminogo,-M; Shibata,-S

ADDRESS OF AUTHOR: Department of Neurosurgery, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

SOURCE: No-Shinkei-Geka. 2001 Apr; 29(4): 353-8

INTERNATIONAL STANDARD SERIAL NUMBER: 0301-2603

PUBLICATION YEAR: 2001

LANGUAGE: Japanese; Non-English

COUNTRY OF PUBLICATION: Japan

ABSTRACT: We reported a case of cerebral arteriovenous malformation (AVM), complicated with intracerebral hemorrhage (ICH), after endovascular embolization. A 51-year-old male suffered from intraventricular hemorrhage due to a rupture of an intranidal aneurysm on October 4, 1999. The first embolization procedure for the aneurysm and a part of the nidus was performed with 2-hydroxyethyl methacrylate-methyl methacrylate (HEMA-MMA) and Liquid coil on day 21 after admission. On day 28, a second embolization was carried out for the residual nidus. Although most of the nidus was obliterated, the patient became comatose 10 hours after the second embolization. Computed tomography revealed a massive ICH in the right parietal lobe, and he underwent emergency evacuation of the hematoma. During the surgery, HEMA-MMA was seen in a draining vein. This caused venous stasis. Although the patient gradually improved postoperatively, he became comatose again because of a recurrence of ICH on day 36. Evacuation of the hematoma and removal of the nidus were performed again. The operative specimen showed AVM embolized by HEMA-MMA with non-specific inflammation and partial inflammatory degeneration of the vascular wall. Hemodynamic change such as venous stasis or elevated pressure of the feeding artery seemed to be the cause of the hemorrhage. Multi-staged embolization with longer intervals and intraoperative flow control were regarded as crucial for avoiding delayed hemorrhage.

MAJOR MESH DESCRIPTORS: *Embolization,-Therapeutic-adverse-effects; *Intracranial-Arteriovenous-Malformations-therapy; *Intracranial-Hemorrhages-etiology

MINOR MESH DESCRIPTORS: Aneurysm,-Ruptured-complications; Intracranial-Aneurysm-complications; Intracranial-Arteriovenous-Malformations-complications; Intracranial-Arteriovenous-Malformations-pathology; Intracranial-Hemorrhages-pathology; Middle-Age; Recurrence-

CHECKTAGS: Case-Report; English-Abstract; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: complications; adverse-effects; pathology; therapy; etiology

SUBSET: Index-Medicus

UPDATE CODE: 20010531

ACCESSION NUMBER: 21242166

RECORD FEATURES: ABSTRACT (AB)

Record 17 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Cerebral intraventricular hemorrhage caused by a large cerebral arteriovenous malformation at 31 years after diagnosis.

AUTHOR: Wang,-Y-C; Lee,-S-D; Chen,-N-F; Shen,-C-C

ADDRESS OF AUTHOR: Department of Neurosurgery, Taichung Veterans General Hospital, 160, Taichung-Kang Road, Sec. 3, Taichung 407, Taiwan. ycwang@vghtc.vghtc.gov.tw

SOURCE: Zhonghua-Yi-Xue-Za-Zhi-(Taipei). 2001 Feb; 64(2): 121-8

INTERNATIONAL STANDARD SERIAL NUMBER: 0578-1337

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: China-(Republic:-1949--)

ABSTRACT: Cerebral arteriovenous malformation (AVM) has an overall 2% to 4% annual risk of hemorrhage. The annual risk of hemorrhage does not decrease with age. However, the natural history of non-operative AVM is difficult to follow up consistently for more than 30 years. In this report, we present a case with a large cerebral AVM which developed a major bleeding causing intraventricular hemorrhage (IVH) 31 years after the diagnosis. A male patient was proved to have a cerebral AVM in the right corpus callosum by cerebral angiography at ages 20 and 28. He was found losing consciousness due to rupture of AVM with IVH at age 51. A small cerebral aneurysm and a dilated vein (aneurysm) of Galen were noted also. A craniotomy with removal of the hematoma and microsurgical resection of the AVM was performed immediately, and the patient regained normal respiration and consciousness about 2 months and 7 months after craniotomy, respectively. We recommend that neurosurgeons should play active roles in encouraging young patients with large AVMs to receive microsurgical resection.

MAJOR MESH DESCRIPTORS: *Cerebral-Hemorrhage-etiology; *Intracranial-Arteriovenous-Malformations-complications

MINOR MESH DESCRIPTORS: Age-Factors; Cerebral-Hemorrhage-radiography; Cerebral-Hemorrhage-surgery; Cerebral-Ventricles; Middle-Age; Time-Factors

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: etiology; radiography; surgery; complications

SUBSET: Index-Medicus

UPDATE CODE: 20010524

ACCESSION NUMBER: 21254760

RECORD FEATURES: ABSTRACT (AB)

Record 18 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Pelvic arteriovenous malformation with iliac vein thrombosis. A case report.

AUTHOR: Chikamatsu,-E; Nagashima,-T; Mizukami,-Y; Ikuta,-K; Sakurai,-T

ADDRESS OF AUTHOR: Department of Surgery, Enshu General Hospital, Hamamatsu, Japan.

SOURCE: J-Cardiovasc-Surg-(Torino). 2001 Feb; 42(1): 115-8

INTERNATIONAL STANDARD SERIAL NUMBER: 0021-9509

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: Italy

ABSTRACT: BACKGROUND: Congenital arteriovenous malformations (AVMs) of the pelvis are relatively rare and are difficult to treat because of diffuse extension and the number of feeding vessels. METHODS: We describe a patient with a pelvic AVM with shunts who also developed iliac vein thrombosis. The AVM was diagnosed during evaluation of what had initially appeared to be a venous stasis ulcer. RESULTS: The ulcer was successfully treated by Palma s procedure, partial resection of the feeding vessels, and transcatheter arterial embolization. CONCLUSIONS: Coexistence of a pelvic AVM with an iliac vein thrombosis has not previously been reported.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-complications; *Iliac-Vein-radiography; *Pelvis-blood-supply; *Venous-Thrombosis-complications

MINOR MESH DESCRIPTORS: Aged-; Arteriovenous-Malformations-radiography; Arteriovenous-Malformations-surgery; Venous-Thrombosis-radiography

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: complications; radiography; surgery; blood-supply

SUBSET: Index-Medicus

UPDATE CODE: 20010524

ACCESSION NUMBER: 21189347

RECORD FEATURES: ABSTRACT (AB)

Record 19 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Cerebellar mutism caused by arteriovenous malformation of the vermis.

AUTHOR: Al-Anazi,-A; Hassounah,-M; Sheikh,-B; Barayan,-S

ADDRESS OF AUTHOR: Department of Neurosurgery King Fahad Hospital of the University, Al-Khobar, Saudi Arabia. alanazil@hotmail.com

SOURCE: Br-J-Neurosurg. 2001 Feb; 15(1): 47-50

INTERNATIONAL STANDARD SERIAL NUMBER: 0268-8697

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: England

ABSTRACT: Transient mutism following posterior fossa tumour resection in children is well known in the literature. To our Knowledge, this phenomenon has never been reported without surgical intervention. We report a case of cerebellar mutism secondary haemorrhage from a vermian arteriovenous malformation (AVM), which resolved to ataxic dysarthria after 6 weeks. Embolization of the AVM was performed and the patient's clinical status continued to improve gradually till she became normal 6 months from the insult. The mutism was due to rupture of the AVM which might correlate the cerebellar mutism with the transient vasospasm of the blood vessels supplying the cerebellum. It is possible for a spontaneus posterior fossa bleed to result in transient mutism similar to post surgical mutism.

MAJOR MESH DESCRIPTORS: *Intracranial-Arteriovenous-Malformations-complications; *Mutism-etiology

MINOR MESH DESCRIPTORS: Adolescence-; Embolization,-Therapeutic-methods; Intracranial-Arteriovenous-Malformations-therapy; Tomography,-X-Ray-Computed-methods; Treatment-Outcome; Unconsciousness-etiology

CHECKTAGS: Case-Report; Female; Human

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: methods; complications; therapy; etiology

SUBSET: Index-Medicus

UPDATE CODE: 20010521

ACCESSION NUMBER: 21198644

RECORD FEATURES: ABSTRACT (AB)

Record 20 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio.

AUTHOR: Sims,-E-C; Plowman,-P-N

ADDRESS OF AUTHOR: Department of Radiotherapy, St Bartholomew's Hospital, West Smithfield, London, UK.

SOURCE: Br-J-Neurosurg. 2001 Feb; 15(1): 28-34

INTERNATIONAL STANDARD SERIAL NUMBER: 0268-8697

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: England

ABSTRACT: Large arteriovenous malformations (AVM) are less likely to be 'cured' by single fraction stereotactically delivered radiation therapy (radiosurgery) and such treatment is attended by higher complication risks. Out of 200 successive AVM patients accepted for curative radiosurgery at St. Bartholomew's Hospital (and all treated by the same 6MV x-ray technique to 17.5 Gy marginal dose) were 62 patients whose target volume exceeded 10 ml. Laboratory data demonstrating that gamma linolenic [omega-6-] acid (GLA) protected rat spinal cord from the damaging effect of single shot radiation prompted this study which employed GLA in conjunction with radiosurgery for large AVM. Without GLA, 41% of large AVM obliterated, but in the GLA treated cohort the obliteration rate was only 5.3% (p < 0.02). The permanent complication rates in the same patient groups were 20% versus 0%, respectively. There was a small skew to smaller volume 'large AVM' in the GLA treated cohort. This fact strengthens the conclusion concerning a difference for AVM obliteration, but could lead to a false conclusion quae GLA modulation of complications. When four patients were censored to minimize this possible bias, the risk for complications in the GLA treated patients was still significantly (p < 0.05), less than in the control group. We therefore conclude: (1) GLA spares AVM from radiation induced obliteration; (2) GLA modifies the response of normal human brain to radiation damage; (3) GLA does not improve the therapeutic ratio for AVM based radiosurgery; (4) GLA may have other uses (notably after radiation accidents and in radiation neuro-oncology, radiation cranial prophylaxis, chemoradiation protocols, whole brain radiation for metastases etc.).

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-surgery; *Radiation-Sensitizing-Agents-administration-and-dosage; *Radiosurgery-methods; *gamma-Linolenic-Acid-administration-and-dosage

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Aged-; Cerebral-Hemorrhage-etiology; Child-; Cohort-Studies; Follow-Up-Studies; Middle-Age; Postoperative-Hemorrhage-etiology; Radiosurgery-adverse-effects; Radiosurgery-standards; Recurrence-; Treatment-Failure

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: surgery; etiology; administration-and-dosage; adverse-effects; methods; standards

CAS REGISTRY NUMBER OR EC NUMBER: 0; 506-26-3

NAME OF SUBSTANCE: Radiation-Sensitizing-Agents; gamma-Linolenic-Acid

SUBSET: Index-Medicus

UPDATE CODE: 20010521

ACCESSION NUMBER: 21198640

RECORD FEATURES: ABSTRACT (AB)

Record 21 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: 3D reconstruction of the encapsulating contour of arteriovenous malformations for radiosurgery using digital subtraction angiography.

AUTHOR: Coste,-E; Gibon,-D; Leclercq,-X; Verdonck,-B; Vasseur,-C; Rousseau,-J

ADDRESS OF AUTHOR: Laboratoire de Biophysique, CHRU de Lille, 59037 Lille, France.

SOURCE: Int-J-Radiat-Oncol-Biol-Phys. 2001 May 1; 50(1): 247-55

INTERNATIONAL STANDARD SERIAL NUMBER: 0360-3016

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: PURPOSE: Treatment planning for radiosurgery depends on the precise definition of radiation target volumes. For vascular pathologies such as arteriovenous malformations (AVM), the most usual technique remains standard X-ray projection imaging, most often carried out under stereotactic conditions. To further benefit from the advantages of two-dimensional digital subtraction angiography (DSA), the authors have developed a method for determining the three-dimensional shape of arteriovenous malformations from two views. METHODS AND MATERIALS: After correction of image intensifier distortion and calibration of both views, the 3D shape of the AVM was determined from two DSA projections using epipolarity geometry. The AVM-encapsulating contour was modeled by triangulation of a stack of almost parallel ellipses. The method was technically validated using artificial targets in a skull phantom. Clinical validation was carried out on 10 patients who were examined using both conventional angiography under stereotactic conditions (SX-ray) and DSA. RESULTS: There was excellent agreement between the artificial target volumes measured with SX-ray and with DSA. The correspondence between AVM volumes found for patients was not as good as with the phantom. CONCLUSIONS: The different image characteristics of the two modalities lead to some differences in AVM estimations. However, the results were sufficiently satisfactory to justify routine use of this AVM modeling technique for radiosurgery planning.

MAJOR MESH DESCRIPTORS: *Angiography,-Digital-Subtraction-methods; *Intracranial-Arteriovenous-Malformations-radiography; *Intracranial-Arteriovenous-Malformations-surgery; *Radiosurgery-methods; *Radiotherapy-Planning,-Computer-Assisted-methods

MINOR MESH DESCRIPTORS: Intracranial-Arteriovenous-Malformations-pathology; Models,-Biological; Phantoms,-Imaging; Radiosurgery-instrumentation; Radiotherapy-Planning,-Computer-Assisted-instrumentation; Reproducibility-of-Results

CHECKTAGS: Comparative-Study; Human; Support,-Non-U.S.-Gov't

PUBLICATION TYPE: Clinical-Trial; Journal-Article

SUBHEADINGS: methods; pathology; radiography; surgery; instrumentation

SUBSET: Index-Medicus

UPDATE CODE: 20010517

ACCESSION NUMBER: 21216629

RECORD FEATURES: ABSTRACT (AB)

Record 22 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Microsurgical treatment of deep arteriovenous malformations--basal ganglia and thalamus.

AUTHOR: Liu,-K-D; Lee,-L-S

ADDRESS OF AUTHOR: Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan. hhlin@vghtpe.gov.tw

SOURCE: Zhonghua-Yi-Xue-Za-Zhi-(Taipei). 2001 Jan; 64(1): 23-30

INTERNATIONAL STANDARD SERIAL NUMBER: 0578-1337

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: China-(Republic:-1949--)

ABSTRACT: BACKGROUND: Surgery for deep nuclei arteriovenous malformations (AVMs) is controversial after the introduction of stereotactic irradiation and embolization. However, rupture of an AVM in this location can lead to catastrophic parenchymal or intraventricular hemorrhage. Thus, microsurgery still has its place in treatment of such lesions to prevent the untreated AVM bleeding or rebleeding. We present a series of 16 AVMs located in the deep nuclei treated by direct microsurgery before radiosurgery was available in 1993. METHODS: We reviewed the clinical and angiographic characteristic of 16 patients with deep-seated AVMs (three in caudate nucleus, three in lentiform nucleus and ten in thalamus). The surgical approach was described separately depending upon the location of the AVMs. The surgical outcomes were classified as excellent (symptoms improved), good (no additional neurological deficit), fair (minor neurological deficit), bad (major neurological deficit) and dead. RESULTS: Complete AVM elimination was achieved in 16 patients (100%) in one-stage operation. Eleven patients had excellent or good outcomes, three had fair outcomes and two had bad outcomes. There were no deaths in this series. Two patients had permanent hemiparesis to make a late morbidity rate of 12.5%. CONCLUSIONS: With improving microsurgical techniques, neuroimaging and neuroanesthesia, difficult and deeply hidden AVMs can be successfully resected under microsurgery with an acceptably low morbidity and mortality rate.

MAJOR MESH DESCRIPTORS: *Basal-Ganglia-surgery; *Intracranial-Arteriovenous-Malformations-surgery; *Thalamus-surgery

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Child-; Microsurgery-; Radiosurgery-

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: surgery

SUBSET: Index-Medicus

UPDATE CODE: 20010503

ACCESSION NUMBER: 21205517

RECORD FEATURES: ABSTRACT (AB)

Record 23 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Growth of occult arteriovenous malformation after cerebral hemorrhage demonstrated by serial magnetic resonance imaging--case report.

AUTHOR: Fuse,-T; Niwa,-Y; Umezu,-M; Yamada,-K

ADDRESS OF AUTHOR: Department of Neurosurgery, National Tohsei Hospital, Shizuoka.

SOURCE: Neurol-Med-Chir-(Tokyo). 2001 Feb; 41(2): 83-6

INTERNATIONAL STANDARD SERIAL NUMBER: 0470-8105

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: Japan

ABSTRACT: A 19-year-old male presented with sudden onset of right hemiparesis caused by left cerebral hemorrhage. Cerebral angiography demonstrated no vascular abnormality, and the hematoma was removed surgically. At operation, no abnormal vascular lesion was found in the brain adjoining the hematoma. Two years later, magnetic resonance (MR) imaging demonstrated a few foci of flow voids adjacent to the hematoma cavity. Four years after the hemorrhage, MR imaging showed more extensive flow-void abnormalities that indicated growth of an occult arteriovenous malformation (AVM). Cerebral angiography indicated a definite AVM supplied mainly by branches of the middle cerebral artery. Total resection of this lesion was performed. The histological diagnosis was typical AVM. Immunohistochemistry with vascular endothelial growth factor showed staining in the walls of the abnormal vessels. Serial MR imaging is very useful for the diagnosis and management of occult AVMs.

MAJOR MESH DESCRIPTORS: *Cerebral-Angiography; *Cerebral-Hemorrhage-diagnosis; *Intracranial-Arteriovenous-Malformations-diagnosis; *Magnetic-Resonance-Imaging

MINOR MESH DESCRIPTORS: Adult-; Cerebral-Hemorrhage-pathology; Cerebral-Hemorrhage-surgery; Follow-Up-Studies; Intracranial-Arteriovenous-Malformations-pathology; Intracranial-Arteriovenous-Malformations-surgery; Middle-Cerebral-Artery-abnormalities; Middle-Cerebral-Artery-pathology; Middle-Cerebral-Artery-surgery; Postoperative-Complications-diagnosis; Postoperative-Complications-pathology; Postoperative-Complications-surgery; Recurrence-; Reoperation-

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnosis; pathology; surgery; abnormalities

SUBSET: Index-Medicus

UPDATE CODE: 20010503

ACCESSION NUMBER: 21151458

RECORD FEATURES: ABSTRACT (AB)

Record 24 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Endovascular management of a bleeding mandibular arteriovenous malformation by transfemoral venous embolization with NBCA.

AUTHOR: Benndorf,-G; Campi,-A; Hell,-B; Holzle,-F; Lund,-J; Bier,-J

ADDRESS OF AUTHOR: Department of Radiology, Virchow Hospital, Charite, Humboldt University Berlin, Germany.

SOURCE: AJNR-Am-J-Neuroradiol. 2001 Feb; 22(2): 359-62

INTERNATIONAL STANDARD SERIAL NUMBER: 0195-6108

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: A 13-year-old boy presented with an arteriovenous malformation (AVM) involving the left mandible that bled after intraoral biopsy. The AVM was treated on an emergency basis by primary intravenous delivery of n-butyl cyanoacrylate after transfemoral catheterization, resulting in complete anatomic and clinical cure.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-complications; *Arteriovenous-Malformations-therapy; *Embolization,-Therapeutic-methods; *Enbucrilate-therapeutic-use; *Hemorrhage-etiology; *Mandible-blood-supply

MINOR MESH DESCRIPTORS: Adolescence-; Arteriovenous-Malformations-radiography; Carotid-Artery,-Common-radiography; Cerebral-Angiography; Femoral-Vein; Phlebography-

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: complications; radiography; therapy; methods; therapeutic-use; etiology; blood-supply

CAS REGISTRY NUMBER OR EC NUMBER: 6606-65-1

NAME OF SUBSTANCE: Enbucrilate

SUBSET: Index-Medicus

UPDATE CODE: 20010503

ACCESSION NUMBER: 21089143

RECORD FEATURES: ABSTRACT (AB)

Record 25 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Identification and anatomic description of the anterior choroidal artery by use of 3D-TOF source and 3D-CISS MR imaging.

AUTHOR: Wiesmann,-M; Yousry,-I; Seelos,-K-C; Yousry,-T-A

ADDRESS OF AUTHOR: Department of Neuroradiology, Klinikum Grosshadern, Munich, Germany.

SOURCE: AJNR-Am-J-Neuroradiol. 2001 Feb; 22(2): 305-10

INTERNATIONAL STANDARD SERIAL NUMBER: 0195-6108

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: BACKGROUND AND PURPOSE: The importance of the anterior choroidal artery (AChA) is related to its supply of crucial anatomic structures, such as the internal capsule. Angiographically, the AChA can be detected in 71% to 98% of patients, but as yet, its visibility on MR images has not been evaluated. Our goal was to assess the sensitivity of MR imaging in the identification of the AChA and its anatomic characteristics. METHODS: Twenty volunteers underwent MR imaging with a 3D time-of-flight (3D-TOF) sequence, 10 of them additionally with a 3D Fourier transformation constructive interference in steady state (3D-CISS) sequence. The MR angiographic source images and the 3D-CISS images were analyzed independently by two neuroradiologists, who evaluated the ability to identify the different segments of the AChA and the posterior communicating artery (PComA) according to a previously defined scoring system (0 = not identified, 1 = most probably identified, 2 = identified with certainty). Additionally, three patients were examined who had an arteriovenous malformation (AVM) supplied by the AChA. RESULTS: In the volunteers, the PComA was identified with certainty in 87.5% on 3D-TOF sequences and in 95% on 3D-CISS sequences; the AChA was identified with certainty in 92.5% on 3D-TOF sequences and in 90% on 3D-CISS sequences. 3D-CISS images showed additional anatomic information in six of 20 vessels. In the three patients, the enlarged AChA was identified with certainty on both imaging sequences. CONCLUSION: The AChA can be reliably identified using both 3D-CISS sequences and the source images of the 3D-TOF sequence. MR imaging can be used to assess and follow-up AChA-related disorders, especially AVMs.

MAJOR MESH DESCRIPTORS: *Arteries-anatomy-and-histology; *Choroid-blood-supply; *Imaging,-Three-Dimensional; *Intracranial-Arteriovenous-Malformations-diagnosis; *Magnetic-Resonance-Imaging-methods; *Magnetic-Resonance-Imaging-standards

MINOR MESH DESCRIPTORS: Adult-; Middle-Age; Reference-Values; Sensitivity-and-Specificity

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Evaluation-Studies; Journal-Article

SUBHEADINGS: anatomy-and-histology; blood-supply; diagnosis; methods; standards

SUBSET: Index-Medicus

UPDATE CODE: 20010503

ACCESSION NUMBER: 21089134

RECORD FEATURES: ABSTRACT (AB)

Record 26 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: [Preliminary results of PET activation study in cerebral arteriovenous malformation (AVM), using C15O2 and 18F-FDG]

AUTHOR: Itosaka,-H; Kuroda,-S; Houkin,-K; Abe,-H; Shiga,-S; Tamaki,-N

ADDRESS OF AUTHOR: Department of Neurosurgery, Hokkaido University Graduate Scholl of Medicine, North 15, West 7, Kitaku, Sapporo, Hokkaido 060-8638, Japan.

SOURCE: No-Shinkei-Geka. 2001 Jan; 29(1): 45-50

INTERNATIONAL STANDARD SERIAL NUMBER: 0301-2603

PUBLICATION YEAR: 2001

LANGUAGE: Japanese; Non-English

COUNTRY OF PUBLICATION: Japan

ABSTRACT: The authors applied PET activation study to two patients with arteriovenous malformation (AVM) to localize primary motor cortex before surgery or embolization. The change in regional cerebral blood flow (rCBF) was measured during foot movements in Case 1 who had a 2-cm AVM located in the post-central gyrus. Superimposed PET/MRI images revealed that the rCBF increase was located in the pre-central gyrus. Its validity was confirmed by intraoperative cortical mapping using electrical median nerve stimulation. The patient safely underwent total removal of AVM. The change in regional cerebral metabolic rate for glucose (rCMRglc) was measured during hand movements in Case 2 who had a huge AVM over the central sulcus. Superimposed PET/MRI images revealed that hand movements significantly increased rCMRglc in the frontal cortex, which was separated from the original primary motor area. The patient safely underwent partial embolization, although he suffered transient weakness of the face after embolization. The preliminary results strongly suggest that PET activation study is useful to localize precisely cortical functions of the patients with AVM, thus reducing morbidity after treatment. The results also suggest that cortical functions may undergo translocation when huge AVM involves the eloquent area.

MAJOR MESH DESCRIPTORS: *Intracranial-Arteriovenous-Malformations-radiography; *Tomography,-Emission-Computed

MINOR MESH DESCRIPTORS: Activation-Analysis; Adult-; Carbon-Radioisotopes-diagnostic-use; Cerebral-Cortex-physiopathology; Fludeoxyglucose-F-18-diagnostic-use; Intracranial-Arteriovenous-Malformations-pathology; Magnetic-Resonance-Imaging; Middle-Age

CHECKTAGS: Case-Report; English-Abstract; Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: diagnostic-use; physiopathology; pathology; radiography

CAS REGISTRY NUMBER OR EC NUMBER: 0; 63503-12-8

NAME OF SUBSTANCE: Carbon-Radioisotopes; Fludeoxyglucose-F-18

SUBSET: Index-Medicus

UPDATE CODE: 20010419

ACCESSION NUMBER: 21087325

RECORD FEATURES: ABSTRACT (AB)

Record 27 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Spinal AVM, epidermal nevus, and rhabdomyosarcoma: A rare neurocutaneous syndrome?

AUTHOR: Schulz,-U; O'Leary,-C-P

ADDRESS OF AUTHOR: Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, Scotland, UK.

SOURCE: Neurology. 2001 Feb 13; 56(3): 395-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0028-3878

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: A 26-year-old man with a history of an embryonal rhabdomyosarcoma arising from the urachus and a large, right-sided, epidermal nevus presented with a rapidly evolving tetraparesis. Investigations confirmed an intramedullary hemorrhage of the cervical spinal cord and an extensive arteriovenous malformation (AVM). An association between his nevus, rhabdomyosarcoma, and spinal AVM is hypothesized.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-pathology; *Nevus-pathology; *Rhabdomyosarcoma,-Embryonal-pathology; *Skin-Neoplasms-pathology; *Spinal-Cord-Diseases-pathology

MINOR MESH DESCRIPTORS: Adult-; Magnetic-Resonance-Imaging

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: pathology

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010405

ACCESSION NUMBER: 21106692

RECORD FEATURES: ABSTRACT (AB)

Record 28 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: [Colonic varices; a case report]

AUTHOR: Kuroki,-S; Kitagawa,-S; Nakajima,-R; Higashihara,-H; Fujiwara,-T

ADDRESS OF AUTHOR: Department of Radiology, Fukuoka University School of Medicine.

SOURCE: Nippon-Igaku-Hoshasen-Gakkai-Zasshi. 2001 Jan; 61(1): 42-4

INTERNATIONAL STANDARD SERIAL NUMBER: 0048-0428

PUBLICATION YEAR: 2001

LANGUAGE: Japanese; Non-English

COUNTRY OF PUBLICATION: Japan

ABSTRACT: Colonic varices is a rare entity that is caused by portal hypertension in most instances. In the case reported here, barium enema and colonoscopy showed multiple tortuous polypoid lesions with intact mucosal surface. Inferior mesenteric angiography showed arteriovenous malformation in the sigmoid colon, complete obstruction of the inferior mesenteric vein, and tortuous dilated marginal veins. We assume that the colonic varices of this case was secondary to complete obstruction of the inferior mesenteric vein following AVM of the sigmoid colon. Close follow-up should is warranted in cases of colonic varices because of the risk of bleeding.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-complications; *Colon-blood-supply; *Sigmoid-blood-supply; *Varicose-Veins-etiology

MINOR MESH DESCRIPTORS: Aged-; Colonoscopy-; Varicose-Veins-diagnosis

CHECKTAGS: Case-Report; English-Abstract; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: complications; blood-supply; diagnosis; etiology

SUBSET: Index-Medicus

UPDATE CODE: 20010405

ACCESSION NUMBER: 21087306

RECORD FEATURES: ABSTRACT (AB)

Record 29 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Risk for hemorrhage during the 2-year latency period following gamma knife radiosurgery for arteriovenous malformations.

AUTHOR: Karlsson,-B; Lax,-I; Soderman,-M

ADDRESS OF AUTHOR: Department of Neurosurgery, Karolinska Hospital, Stockholm, Sweden.

SOURCE: Int-J-Radiat-Oncol-Biol-Phys. 2001 Mar 15; 49(4): 1045-51

INTERNATIONAL STANDARD SERIAL NUMBER: 0360-3016

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: PURPOSE: Radiosurgery does not immediately obliterate an arteriovenous malformation (AVM), and the risk for hemorrhage still persists until the AVM is occluded. There is controversy about whether this risk is altered after as compared to before radiosurgery. The aim of this paper is to study this topic further and to suggest a model to predict the risk for posttreatment hemorrhage. METHODS AND MATERIALS: The incidence of hemorrhages within the first 24 months following Gamma Knife radiosurgery was studied retrospectively among 1593 AVM patients, and was related to patient, AVM, and treatment parameters. RESULTS: Fifty-six patients experienced a hemorrhage in the latency period, representing an average annual incidence of 1.8%. The incidence of posttreatment hemorrhage was related to the patient's age, AVM volume, minimum dose, and average dose delivered to the AVM nidus. Based on these observations, an equation was defined that could quantify the probability for a posttreatment hemorrhage to occur. CONCLUSION: A model that can predict the probability for a hemorrhage within the first 24 months after radiosurgery is presented. The risk is higher for larger AVMs and for older patients, and it is lower when higher doses of radiation are used.

MAJOR MESH DESCRIPTORS: *Algorithms-; *Intracranial-Arteriovenous-Malformations-surgery; *Intracranial-Hemorrhages-epidemiology; *Radiosurgery-

MINOR MESH DESCRIPTORS: Adult-; Age-Factors; Incidence-; Intracranial-Arteriovenous-Malformations-complications; Radiotherapy-Dosage; Retrospective-Studies; Risk-Assessment; Time-Factors

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: complications; surgery; epidemiology

SUBSET: Index-Medicus

UPDATE CODE: 20010329

ACCESSION NUMBER: 21135729

RECORD FEATURES: ABSTRACT (AB)

Record 30 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Developmental venous anomaly with an arteriovenous shunt and a thrombotic complication. Case report.

AUTHOR: Agazzi,-S; Regli,-L; Uske,-A; Maeder,-P; de-Tribolet,-N

ADDRESS OF AUTHOR: Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

SOURCE: J-Neurosurg. 2001 Mar; 94(3): 533-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0022-3085

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: Developmental venous anomalies (DVAs) are common congenital variations of normal venous drainage that are known for their benign natural history. Isolated cases of symptomatic DVAs with associated arteriovenous (AV) shunts have recently been reported. The present case, in which thrombosis occurred in a DVA involving an AV shunt, raises intriguing questions regarding the clinical characteristics of these lesions and can be used to argue in favor of considering such lesions to be arteriovenous malformations (AVMs). A 39-year-old man presented with acute thrombosis in a complex system of anomalous hemispheric venous drainage, which included two distinct DVAs, one of which involved an AV shunt. The hemodynamic turbulences induced by a communication between shunted and normal venous outflows were the possible predisposing factor of the thrombosis. Follow-up angiographic and magnetic resonance images revealed complete recanalization of the thrombosed vessel and provided a thorough visualization of the particular angioarchitecture of the DVA. Acute thrombosis within a DVA with an AV shunt has not been reported previously and, thus, this case can be added to other reports of complications that arise in this particular type of DVA. The authors hypothesize that the presence of an AV shunt in a DVA is a risk factor for aggressive clinical behavior of the anomaly, rendering those lesions prone to complications similar to AVMs. Although no treatment can be offered, the presence of an AV shunt in a DVA warrants close follow-up observation because such lesions may represent a particular subtype of AVM and, therefore, may exhibit an aggressive clinical behavior.

MAJOR MESH DESCRIPTORS: *Cerebral-Veins-abnormalities; *Intracranial-Arteriovenous-Malformations-complications; *Intracranial-Arteriovenous-Malformations-pathology; *Intracranial-Thrombosis-etiology; *Intracranial-Thrombosis-pathology

MINOR MESH DESCRIPTORS: Adult-; Cerebral-Angiography; Venous-Thrombosis-etiology; Venous-Thrombosis-pathology

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article; Review; Review-of-Reported-Cases

SUBHEADINGS: abnormalities; complications; pathology; etiology

SUBSET: Abridged-Index-Medicus; Index-Medicus

UPDATE CODE: 20010329

ACCESSION NUMBER: 21130693

RECORD FEATURES: ABSTRACT (AB)

Record 31 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Recurrence of a cerebral arteriovenous malformation after surgical excision.

AUTHOR: Freudenstein,-D; Duffner,-F; Ernemann,-U; Rachinger,-J; Grote,-E

ADDRESS OF AUTHOR: Department of Neurosurgery, Eberhard-Karls University, Tubingen, Germany.

SOURCE: Cerebrovasc-Dis. 2001; 11(1): 59-64

INTERNATIONAL STANDARD SERIAL NUMBER: 1015-9770

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: Switzerland

ABSTRACT: Complete resection of a cerebral arteriovenous malformation (AVM) should eliminate the future risk of an associated intracranial bleeding. Because total removal of an AVM may be difficult to assess at the time of surgery, postoperative angiography has become the accepted standard for documenting that complete removal has been achieved. However, even angiographically confirmed excision of an AVM does not completely exclude the possibility of rebleeding. Regrowth of an AVM with subsequent haemorrhage has been documented in children and is attributed to forces acting on the immature vasculature. The authors report the case of a 21-year-old man whose AVM recurred 5 years after angiographically proven complete excision. According to the presented case, the authors emphasise that, even in adults, angiographic documentation of total removal does not always eliminate the risk of reformation of an AVM. Copyright 2001 S. Karger AG, Basel.

MAJOR MESH DESCRIPTORS: *Intracranial-Arteriovenous-Malformations-surgery

MINOR MESH DESCRIPTORS: Adult-; Cerebral-Angiography; Intracranial-Arteriovenous-Malformations-radiography; Recurrence-; Time-Factors; Tomography,-X-Ray-Computed

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: radiography; surgery

SUBSET: Index-Medicus

UPDATE CODE: 20010329

ACCESSION NUMBER: 21111500

RECORD FEATURES: ABSTRACT (AB)

Record 32 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Stereotactic radiosurgery for motor cortex region arteriovenous malformations.

AUTHOR: Hadjipanayis,-C-G; Levy,-E-I; Niranjan,-A; Firlik,-A-D; Kondziolka,-D; Flickinger,-J-C; Lunsford,-L-D

ADDRESS OF AUTHOR: Department of Neurological Surgery, University of Pittsburgh Medical Center, Pennsylvania, USA.

SOURCE: Neurosurgery. 2001 Jan; 48(1): 70-6; discussion 76-7

INTERNATIONAL STANDARD SERIAL NUMBER: 0148-396X

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: OBJECTIVE: The optimal management of arteriovenous malformations (AVMs) in critical brain locations remains controversial. To reduce the risk of an AVM hemorrhage and to enhance the possibility of preserving neurological function, stereotactic radiosurgery was performed in 33 patients with newly diagnosed or residual AVMs located within the motor cortex. The role of embolization also was examined. METHODS: During a 9-year study period, 33 patients with AVMs located primarily in the motor cortex region were treated with stereotactic radiosurgery. These patients were followed up radiographically for a minimum of 36 months, or less if obliteration was documented before 36 months had elapsed. Of the 33 patients, 9 underwent embolization and 1 underwent microsurgery before radiosurgery. Nine patients required a second radiosurgery. The mean AVM target volume was 4.35 cc, and the average radiation dose to the AVM margin was 20 Gy. The median follow-up was 36 months (range, 10-91 mo), and angiographic follow-up of eligible patients was performed 24 or 36 months after radiosurgery. RESULTS: Results were stratified by radiosurgical target volumes: less than 3 cc (Group 1), 3 to 10 cc (Group 2), and greater than 10 cc (Group 3). Overall (including second radiosurgery), 13 (87%) of 15 patients in Group 1 had complete obliteration confirmed by angiography. Nine (64%) of 14 patients in Group 2 exhibited nidus obliteration, and one (25%) of four patients in Group 3 demonstrated obliteration on a magnetic resonance imaging scan. Eight patients (24%) underwent second-stage radiosurgery after angiography revealed a persistent AVM nidus; three patients demonstrated complete obliteration on follow-up angiography. The obliteration rate was higher (87%) for AVMs with less than 3 cc target volume and lower (56%) for those with target volumes larger than 3 cc. One patient experienced worsening neurological function after radiosurgery, and one died from delayed AVM hemorrhage during the latency period. No patient bled after angiographically confirmed AVM obliteration. CONCLUSION: Stereotactic radiosurgery is a successful and safe management option for patients with motor cortex AVMs. The obliteration of AVMs and the attendant low morbidity rates indicate a primary role for radiosurgery in these patients. Staged radiosurgery may be necessary to increase obliteration rates for larger AVMs or for those that are not obliterated after the first procedure.

MAJOR MESH DESCRIPTORS: *Intracranial-Arteriovenous-Malformations-surgery; *Motor-Cortex-blood-supply; *Radiosurgery-adverse-effects; *Stereotaxic-Techniques

MINOR MESH DESCRIPTORS: Adolescence-; Adult-; Aged-; Anticonvulsants-therapeutic-use; Cerebral-Angiography; Child-; Follow-Up-Studies; Headache-etiology; Intracranial-Arteriovenous-Malformations-complications; Intracranial-Arteriovenous-Malformations-diagnosis; Magnetic-Resonance-Imaging; Middle-Age; Seizures-drug-therapy; Seizures-etiology; Treatment-Outcome

CHECKTAGS: Female; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: therapeutic-use; etiology; complications; diagnosis; surgery; blood-supply; adverse-effects; drug-therapy

CAS REGISTRY NUMBER OR EC NUMBER: 0

NAME OF SUBSTANCE: Anticonvulsants

SUBSET: Index-Medicus

UPDATE CODE: 20010308

ACCESSION NUMBER: 21025668

RECORD FEATURES: ABSTRACT (AB)

Record 33 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Vascular orientation by intra-arterial dye injection during spinal arteriovenous malformation surgery.

AUTHOR: Tani,-S; Ikeuchi,-S; Hata,-Y; Abe,-T

ADDRESS OF AUTHOR: Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan. tani@jikei.ac.jp

SOURCE: Neurosurgery. 2001 Jan; 48(1): 240-2

INTERNATIONAL STANDARD SERIAL NUMBER: 0148-396X

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: United-States

ABSTRACT: OBJECTIVE: Rich and complicated vascular structures on the spinal cord often interfere with obliteration of a spinal arteriovenous malformation (AVM). Vascular orientation during spinal AVM surgery is essential. The authors recently performed six consecutive spinal AVM surgeries in five patients (two with perimedullary AVMs, and three with dural arteriovenous fistulae) with the aid of intra-arterial injection of dye (indigo carmine). METHODS: Two representative cases are described. A microcatheter was placed preoperatively in the artery of interest. Subsequent to the exposure of the vascular complex, a 1-ml injection of indigo carmine (2 mg/ml) clearly demonstrated the feeding arteries and the draining veins around the AVM or dural arteriovenous fistula. RESULTS: One patient had repeat surgery because of incomplete obliteration of the AVM owing to migration of the catheter. All patients, except one who had temporary postoperative deterioration and persistent neurological deficits, had good surgical outcomes, however. No apparent side effects caused by the dye were reported. CONCLUSION: The assistance system for spinal AVM surgery is easy and safe and can be applied in other surgical institutions.

MAJOR MESH DESCRIPTORS: *Arteriovenous-Malformations-surgery; *Indigo-Carmine-diagnostic-use; *Spinal-Cord-blood-supply

MINOR MESH DESCRIPTORS: Angiography-; Arteriovenous-Malformations-radiography; Dyes-administration-and-dosage; Dyes-diagnostic-use; Indigo-Carmine-administration-and-dosage; Injections,-Intra-Arterial; Middle-Age; Postoperative-Complications; Spinal-Cord-radiography; Treatment-Outcome

CHECKTAGS: Case-Report; Human; Male

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: radiography; surgery; administration-and-dosage; diagnostic-use; blood-supply

CAS REGISTRY NUMBER OR EC NUMBER: 0; 860-22-0

NAME OF SUBSTANCE: Dyes; Indigo-Carmine

SUBSET: Index-Medicus

UPDATE CODE: 20010308

ACCESSION NUMBER: 21025691

RECORD FEATURES: ABSTRACT (AB)

Record 34 of 34 in MEDLINE(R) on CD 2001/01-2001/06

TITLE: Contribution of neurons to habituation to mechanical stimulation in Caenorhabditis elegans.

AUTHOR: Kitamura,-K-I; Amano,-S; Hosono,-R

ADDRESS OF AUTHOR: Department of Physical Information, Faculty of Medicine, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan.

SOURCE: J-Neurobiol. 2001 Jan; 46(1): 29-40

INTERNATIONAL STANDARD SERIAL NUMBER: 0022-3034

PUBLICATION YEAR: 2001

LANGUAGE: English

COUNTRY OF PUBLICATION: UNITED-STATES

ABSTRACT: In Caenorhabditis elegans, a light touch induces a locomotor response. Repeated touches, however, result in an attenuation of response, that is, habituation. Withdrawal responses elicited by anterior touch are controlled by anterior mechanosensory neurons (AVM and ALMs), and by four pairs of interneurons (AVA, AVB, AVD, and PVC) (Chalfie et al., 1985; White et al., 1986). To identify the neurons that participate in habituation, we ablated these neurons with a laser microbeam and investigated the resulting habituation of the operated animals. The animals lacking both left and right homologues AVDLR were habituated more rapidly than intact animals. We propose that chemical synapses at AVD play a critical role in the habituation of intact animals. Copyright 2000 John Wiley & Sons, Inc.

MAJOR MESH DESCRIPTORS: *Caenorhabditis-elegans-physiology; *Habituation-Psychophysiology-physiology; *Interneurons-physiology; *Mechanoreceptors-physiology

MINOR MESH DESCRIPTORS: Caenorhabditis-elegans-cytology; Interneurons-cytology; Laser-Surgery; Learning-physiology; Mechanoreceptors-cytology; Movement-physiology; Neural-Pathways-cytology; Neural-Pathways-physiology; Neural-Pathways-surgery; Physical-Stimulation; Touch-physiology

CHECKTAGS: Animal; Support,-Non-U.S.-Gov't

PUBLICATION TYPE: Journal-Article

SUBHEADINGS: cytology; physiology; surgery

SUBSET: Index-Medicus

UPDATE CODE: 20010208

ACCESSION NUMBER: 20560879

RECORD FEATURES: ABSTRACT (AB)


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