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ELLIS-VAN CREVELD SYNDROME 01: the 1991-1995 literature


A literature search at Indiana University, Bloomington, Indiana

Ellis-van Creveld syndrome, also known as chrondro-ectodermal dysplasia, is an autosomal recessive condition that typically involves: a) malformations of certain cartilages (especially those derived from "neural crest" cells, i. e., branchiomeric cartilages); b) malformed, atretic or absence of some glands and ducts (e. g. bile duct); c) polydactyly. Some fifty percent of afflicted persons also have defects in the heart. In extremely rare instances (one recorded in the Medline literature) Ellis-van Creveld syndrome has occurred along with agenesis of the corpus callosum.
The following MEDLINE items were compiled in response to a Shufflebrain reader's inquiry about agenesis of the corpus callosum and are presented with the generous co-operation and kind permission of SilverPlatter
MEDLINE EXPRESS (R) 1991-1995 1 of 24

TI: Single atrium, atrioventricular canal/postaxial hexodactyly indicating Ellis-van Creveld syndrome [letter; comment]

CM: Comment on: Hum Genet 1994 Jul;94(1):104-6

AU: Digilio-MC; Marino-B; Giannotti-A; Dallapiccola-B

SO: Hum-Genet. 1995 Aug; 96(2): 251-3

ISSN: 0340-6717

PY: 1995

LA: ENGLISH

CP: GERMANY

MESH: Adult-; Foot-Deformities,-Congenital; Hand-Deformities,-Congenital; Heart-Atrium-abnormalities; Heart-Defects,-Congenital; Infant,-Newborn; Tooth-Abnormalities

MESH: *Ellis-Van-Creveld-Syndrome-diagnosis

TG: Case-Report; Female; Human; Male

PT: COMMENT; LETTER

AN: 95362264

UD: 9511

MEDLINE EXPRESS (R) 1991-1995 2 of 24

TI: Symptomatic heterozygosity in the Ellis-van Creveld syndrome?

AU: Spranger-S; Tariverdian-G

AD: Institute of Human Genetics and Anthropology, University of Heidelberg, Germany.

SO: Clin-Genet. 1995 Apr; 47(4): 217-20

ISSN: 0009-9163

PY: 1995

LA: ENGLISH

CP: DENMARK

AB: A 13-month-old girl with Ellis-van Creveld syndrome and her mildly affected father are described. We discuss whether the father is a symptomatic heterozygote of the Ellis-van Creveld syndrome or an untypical affected patient with Weyers' acrodental dysostosis.

MESH: Adult-; Ellis-Van-Creveld-Syndrome-pathology; Heterozygote-; Infant-; Pedigree-

MESH: *Ellis-Van-Creveld-Syndrome-genetics

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 95354330

UD: 9511

MEDLINE EXPRESS (R) 1991-1995 3 of 24

TI: Common atrium with Ebstein's anomaly in a neonate with Ellis-van Creveld syndrome.

AU: Chang-YC; Wu-JM; Lin-SJ; Wu-MH

AD: Department of Pediatrics, National Cheng Kung University Hospital, Tainan, Taiwan, R.O.C.

SO: Acta-Paediatr-Sin. 1995 Jan-Feb; 36(1): 50-2

ISSN: 0001-6578

PY: 1995

LA: ENGLISH

CP: TAIWAN

AB: A female newborn with characteristic multiple anomalies of Ellis-van Creveld syndrome is reported. Common atrium with Ebstein's malformation of the tricuspid valve was diagnosed by serial echocardiographic examinations. Such a combination of cardiac anomalies have not previously been reported in this syndrome.

MESH: Infant,-Newborn

MESH: *Ebstein's-Anomaly-complications; *Ellis-Van-Creveld-Syndrome-complications

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE

AN: 95297349

UD: 9509

MEDLINE EXPRESS (R) 1991-1995 4 of 24

TI: Del(12)(p11.21p12.2) associated with an asphyxiating thoracic dystrophy or chondroectodermal dysplasia-like syndrome.

AU: Nagai-T; Nishimura-G; Kato-R; Hasegawa-T; Ohashi-H; Fukushima-Y

AD: Division of Pediatrics, Tokyo Metropolitan Kiyose Children's Hospital, Japan.

SO: Am-J-Med-Genet. 1995 Jan 2; 55(1): 16-8

ISSN: 0148-7299

PY: 1995

LA: ENGLISH

CP: UNITED-STATES

AB: We describe a 5-year-old Japanese boy who has some radiographic findings characteristic of asphyxiating thoracic dystrophy (ATD)-chondroectodermal dysplasia with a de novo chromosome abnormality. He also has mild mental retardation, short stature, hypoplastic hair and skin, oligodontia, small thoracic cage, hypoplastic pelvis and cone-shaped epiphyses of hands. On cytogenetic studies he was found to have a de novo del(12)(p11.21p12.2). These results suggest that the locus of the gene associated with ATD-chondroectodermal dysplasia may be situated at 12p11.21p12.2.

MESH: Child,-Preschool; Chromosome-Banding; Epiphyses-abnormalities; Pelvic-Bones-abnormalities

MESH: *Chromosome-Deletion; *Chromosomes,-Human,-Pair-12; *Ellis-Van-Creveld-Syndrome-genetics; *Thorax-abnormalities

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 95216651

UD: 9507

MEDLINE EXPRESS (R) 1991-1995 5 of 24

TI: Ellis-van Creveld syndrome (chondroectodermal dysplasia).

AU: Avolio-A Jr; Berman-AT; Israelite-CL

AD: Department of Orthopedics, Hahnemann University, Philadelphia, PA 19102.

SO: Orthopedics. 1994 Aug; 17(8): 735-7

ISSN: 0147-7447

PY: 1994

LA: ENGLISH

CP: UNITED-STATES

MESH: Child-; Dwarfism-complications; Ellis-Van-Creveld-Syndrome-complications

MESH: *Ellis-Van-Creveld-Syndrome-radiography

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 95061683

UD: 9502

MEDLINE EXPRESS (R) 1991-1995 6 of 24

TI: [The Ellis-Van Creveld syndrome. Apropos 2 clinical cases]

TO: Sindrome de Ellis-Van Creveld. A proposito de dois casos clinicos.

AU: Santos-JM; Pipa-J; Antunes-L; Neves-O; Nascimento-C; Cabral-C; Costa-A; Barros-O; Carvalho-J; Angelo-F; et-al

AD: Internato Complementar de Cardiologia, Hospital Distrital de Viseu.

SO: Rev-Port-Cardiol. 1994 Jan; 13(1): 45-50, 8

ISSN: 0304-4750

PY: 1994

LA: PORTUGUESE; NON-ENGLISH

CP: PORTUGAL

AB: The chondroectodermal dysplasia--Ellis-Van Creveld Syndrome--is an unusual form of congenital disease, genetically transmitted with a recessive autosomal pattern, which involves the skeletal system, nails and teeth. In about 50 to 60 percent of cases, the affected individuals show cardiac abnormalities, and the most common are single atrium, large atrial septal defect, ostium primum type. Other abnormalities may accompany these lesions, such as aortic atresia, hypoplasia of the ascending aorta or of the left ventricle. About half of the patients die in the childhood due to cardiorespiratory complications. Two cases are described with this syndrome, a male and a female, with 54 and 45 years old respectively; they were followed in our Departments and showed congestive heart failure and single atrium. These cases led us to review the subject; we believe that the unusual longevity of these patients can be related to their relatively benign cardiac disease.

MESH: Ellis-Van-Creveld-Syndrome-complications; English-Abstract; Heart-Atrium-abnormalities; Heart-Defects,-Congenital-etiology; Heart-Failure,-Congestive-etiology; Middle-Age

MESH: *Ellis-Van-Creveld-Syndrome-diagnosis; *Heart-Defects,-Congenital-diagnosis; *Heart-Failure,-Congestive-diagnosis

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 94206569

UD: 9407

MEDLINE EXPRESS (R) 1991-1995 7 of 24

TI: Short limbed dwarfism, genital hypoplasia, sparse hair, and vertebral anomalies: a variant of Ellis-van Creveld syndrome?

AU: Fryns-JP; Moerman-P

AD: Centre for Human Genetics, Leuven, Belgium.

SO: J-Med-Genet. 1993 Apr; 30(4): 322-4

ISSN: 0022-2593

PY: 1993

LA: ENGLISH

CP: ENGLAND

AB: A male newborn with acromesomelic short limbed dwarfism, genital hypoplasia, and vertebral anomalies is reported. As the child had an important number of clinical and radiological symptoms seen in patients with Ellis-van Creveld syndrome, we raise the question of whether he may represent a variant example of this syndrome despite the absence of cardinal symptoms such as postaxial polydactyly and ectodermal changes (nail hypoplasia).

MESH: Abnormalities,-Multiple-genetics; Ellis-Van-Creveld-Syndrome-genetics; Heart-Defects,-Congenital-genetics; Infant,-Newborn; Phenotype-

MESH: *Bone-and-Bones-abnormalities; *Dwarfism-genetics; *Ellis-Van-Creveld-Syndrome-diagnosis; *Genitalia,-Male-abnormalities; *Hair-abnormalities

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 93253754

UD: 9308

MEDLINE EXPRESS (R) 1991-1995 8 of 24

TI: Skeletal histopathology in fetuses with chondroectodermal dysplasia (Ellis-van Creveld syndrome).

AU: Qureshi-F; Jacques-SM; Evans-MI; Johnson-MP; Isada-NB; Yang-SS

AD: Department of Pathology, Hutzel Hospital, Detroit, MI 48201.

SO: Am-J-Med-Genet. 1993 Feb 15; 45(4): 471-6

ISSN: 0148-7299

PY: 1993

LA: ENGLISH

CP: UNITED-STATES

AB: Chondroectodermal dysplasia (CED) is an uncommon autosomal recessive disorder and one of the short rib polydactyly syndromes (SRPS). It is characterized by acromelic and mesomelic shortness of limbs, postaxial polydactyly, small chest, ectodermal dysplasia, and in many cases, congenital heart defects. Controversy exists over possible changes in the growth plate. With the advent of ultrasonographic examination, increasing numbers of fetuses with osteochondrodysplasias are examined by pathologists. Since histopathologic examination of the skeletal system is useful in defining various osteochondrodysplasias and it has not been described in the fetus with CED, we herein describe 3 cases of fetal CED with emphasis on skeletal histopathology. All 3 pregnancies were terminated at 22-23 weeks because of ultrasonographic demonstration of short limbs and growth retardation. Radiologically, each fetus had acromelic and mesomelic shortness of long bones with smooth round metaphyses, vertically short iliac bones, short ribs and normal vertebrae. These findings are similar to those described in the larger newborn infant with CED. Histopathologically, the cartilage of the long bones showed chondrocytic disorganization in the physeal growth zone. The findings are dissimilar to those of larger infants and older children in whom chondrocytic columnization has been seen in the central physis and disorganization in peripheral physis. Furthermore, a variable degree of chondrocytic disorganization was also seen in the central physeal growth zone of vertebrae in these fetuses. Other findings noted at fetopsy were: polydactyly in all 3 cases, congenital heart defect in 2 and an abnormal frenulum in one case. The foregoing phenotypic and radiographic manifestations and skeletal histopathology help separate CED from other SRPS.

MESH: Bone-and-Bones-radiography; Bone-and-Bones-ultrasonography; Ellis-Van-Creveld-Syndrome-radiography; Ellis-Van-Creveld-Syndrome-ultrasonography; Fetal-Diseases-radiography; Fetal-Diseases-ultrasonography; Infant,-Newborn; Prenatal-Diagnosis; Xeroradiography-

MESH: *Bone-and-Bones-pathology; *Ellis-Van-Creveld-Syndrome-pathology; *Fetal-Diseases-pathology

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 93220716

UD: 9307

MEDLINE EXPRESS (R) 1991-1995 9 of 24

TI: The Ellis-Van Creveld Foundation [letter]

AU: Sutton-Y; Sutton-C

SO: Health-Visit. 1993 Jan; 66(1): 32

ISSN: 0017-9140

PY: 1993

LA: ENGLISH

CP: ENGLAND

MESH: Child,-Preschool; Ellis-Van-Creveld-Syndrome-genetics

MESH: *Ellis-Van-Creveld-Syndrome-psychology; *Family-psychology; *Self-Help-Groups-organization-and-administration

TG: Case-Report; Female; Human

PT: LETTER

AN: 93194595

UD: 9306

SB: NURSING

MEDLINE EXPRESS (R) 1991-1995 10 of 24

TI: [Ellis van Creveld syndrome (chondroectodermal dysplasia) in a 7 year old girl]

TO: Zespol Ellisa van Crevelda (dysplazja chonderoektodermalna) U 7-letniej dziewczynki.

AU: Zoch-Zwierz-W; Iwaszkiewicz-Powlowska-A; Wiercinski-R; Hubert-E; Winiecka-W; Biernaka-A

AD: I Kliniki Chorob Dzieci Ak. Med., Bialymstoku.

SO: Wiad-Lek. 1992 Nov; 45(21-22): 866-9

ISSN: 0043-5147

PY: 1992

LA: POLISH; NON-ENGLISH

CP: POLAND

MESH: Child-; English-Abstract

MESH: *Ellis-Van-Creveld-Syndrome

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE

AN: 93227630

UD: 9307

MEDLINE EXPRESS (R) 1991-1995 11 of 24

TI: Ellis-van Creveld syndrome in a Western Australian aboriginal community. Postaxial polydactyly as a heterozygous manifestation?

AU: Goldblatt-J; Minutillo-C; Pemberton-PJ; Hurst-J

AD: Princess Margaret Hospital for Children, Perth, WA.

SO: Med-J-Aust. 1992 Aug 17; 157(4): 271-2

ISSN: 0025-729X

PY: 1992

LA: ENGLISH

CP: AUSTRALIA

AB: OBJECTIVE: To report two children with Ellis-van Creveld syndrome in an extended kindred of Western Australian Aboriginal descent. Furthermore, to document two family members with isolated postaxial polydactyly of the feet as probable heterozygous manifestations of the Ellis-van Creveld gene. CLINICAL FEATURES: Male and female second cousins with short limbs, postaxial polydactyly and cardiac malformations are described. CONCLUSIONS: It is proposed that founder effect and random genetic drift resulted in a relatively high frequency of the Ellis-van Creveld gene in the Aboriginal people of Western Australia. In addition, further evidence is provided for the postulate that isolated postaxial polydactyly is a heterozygous manifestation of the gene.

MESH: Heterozygote-; Infant-; Pedigree-

MESH: *Aborigines-genetics; *Australoid-Race-genetics; *Ellis-Van-Creveld-Syndrome-genetics; *Fingers-abnormalities; *Toes-abnormalities

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 93062334

UD: 9302

MEDLINE EXPRESS (R) 1991-1995 12 of 24

TI: Chondro-ectodermal dysplasia.

AU: Maitra-TK; Acharyya-B; Chatterjee-RN; Das-AK

AD: BC Roy Polio Clinic, Calcutta.

SO: J-Indian-Med-Assoc. 1992 Apr; 90(4): 108

ISSN: 0019-5847

PY: 1992

LA: ENGLISH

CP: INDIA

MESH: Child-; Ellis-Van-Creveld-Syndrome-pathology; Ellis-Van-Creveld-Syndrome-radiography

MESH: *Ellis-Van-Creveld-Syndrome-diagnosis

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 92355922

UD: 9211

MEDLINE EXPRESS (R) 1991-1995 13 of 24

TI: Ellis-van Creveld syndrome.

AU: Ghosh-S; Saha-AK; Bhowmik-P

AD: Medical College, Calcutta.

SO: J-Indian-Med-Assoc. 1992 Mar; 90(3): 71

ISSN: 0019-5847

PY: 1992

LA: ENGLISH

CP: INDIA

MESH: Child-; Ellis-Van-Creveld-Syndrome-diagnosis; Ellis-Van-Creveld-Syndrome-genetics; Ellis-Van-Creveld-Syndrome-ultrasonography; India-

MESH: *Ellis-Van-Creveld-Syndrome

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE

AN: 92340919

UD: 9210

MEDLINE EXPRESS (R) 1991-1995 14 of 24

TI: Quiz. Ellis-Van Creveld syndrome or chondroectodermic dysplasia.

AU: Preti-P; Stilli-S; Donzelli-O; Marchiodi-L

AD: Divisione di Ortopedia e Traumatologia Infantile, Istituto Ortopedico Rizzoli, Bologna.

SO: Chir-Organi-Mov. 1991 Jan-Mar; 76(1): 87-91

ISSN: 0009-4749

PY: 1991

LA: ENGLISH; ITALIAN

CP: ITALY

MESH: Diagnosis,-Differential; Infant-; Nomenclature-

MESH: *Ellis-Van-Creveld-Syndrome-diagnosis

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 91372018

UD: 9112

MEDLINE EXPRESS (R) 1991-1995 15 of 24

TI: Postaxial polydactyly as heterozygote manifestation in Ellis-Van Creveld syndrome? [letter; comment]

CM: Comment on: Am J Med Genet 1990 May;36(1):37-42

AU: Fryns-JP

SO: Am-J-Med-Genet. 1991 Jun 15; 39(4): 500-1

ISSN: 0148-7299

PY: 1991

LA: ENGLISH

CP: UNITED-STATES

MESH: Infant,-Newborn

MESH: *Ellis-Van-Creveld-Syndrome-genetics; *Fingers-abnormalities; *Heterozygote-

TG: Human

PT: COMMENT; LETTER

AN: 91345062

UD: 9111

MEDLINE EXPRESS (R) 1990 16 of 24

TI: [Asphyxiating thoracic dysplasia associated with hepatic ductal hypoplasia, agenesis of the corpus callosum and Dandy-Walker syndrome]

TO: Dystrophie thoracique asphyxiante de Jeune associee a une hypoplasie ductulaire hepatique, une agenesie du corps calleux et un syndrome de Dandy-Walker.

AU: Trabelsi-M; Hammou-Jeddi-A; Kammoun-A; Bennaceur-B; Gharbi-HA

AD: Service de pediatrie, hopital d'enfants de Tunis, Tunisie.

SO: Pediatrie-Bucur. 1990; 45(1): 35-8

ISSN: 0031-4021

PY: 1990

LA: FRENCH; NON-ENGLISH

CP: FRANCE

AB: The authors report on a case of a newborn with asphyxiating thoracic dysplasia who died 36 h after birth. This chondrodysplasia was associated with hepatic ductular hypoplasia, agenesis of the corpus callosum and Dandy-Walker malformation. To our knowledge, such an association has not previously been reported in the literature.

MESH: English-Abstract; Infant,-Newborn

MESH: *Bile-Ducts,-Intrahepatic-abnormalities; *Cholestasis,-Intrahepatic-complications; *Corpus-Callosum-abnormalities; *Dandy-Walker-Syndrome-complications; *Ellis-Van-Creveld-Syndrome-complications; *Hydrocephalus-complications; *Thorax-abnormalities

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE; REVIEW; REVIEW,-TUTORIAL

AN: 90221681

UD: 9007

MEDLINE EXPRESS (R) 1990 17 of 24

TI: [A case of Ellis-van Creveld syndrome]

TO: Przypadek zespolu Ellisa-van Crevelda.

AU: Postek-G

AD: Oddzialu Wewnetrznego Szpitala Dzieciecego w Toruniu.

SO: Pol-Tyg-Lek. 1990 Sep 17-24; 45(38-39): 787-9

ISSN: 0032-3756

PY: 1990

LA: POLISH; NON-ENGLISH

CP: POLAND

AB: A case of the Ellis-van Creveld syndrome in a 18-year girl with congenital disturbances is presented. In the patients described they were coexisting with insulin dependent diabetes mellitus.

MESH: Adolescence-; Diabetes-Mellitus,-Insulin-Dependent-complications; Ellis-Van-Creveld-Syndrome-complications; English-Abstract

MESH: *Diabetes-Mellitus,-Insulin-Dependent-diagnosis; *Ellis-Van-Creveld-Syndrome-diagnosis

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE

AN: 91252395

UD: 9109

MEDLINE EXPRESS (R) 1990 18 of 24

TI: [Ellis van Creveld syndrome]

TO: Sindrome de Ellis van Creveld.

AU: Salvador-Amores-AM; Grande-Baos-C; Blanco-Caneda-ML; Alonso-Ortiz-T; Moro-Serrano-M; Arrabal-Teran-MC

AD: Departamento de Pediatria, Hospital Clinico Universitario de San Carlos, Madrid.

SO: An-Esp-Pediatr. 1990 May; 32(5): 445-50

ISSN: 0302-4342

PY: 1990

LA: SPANISH; NON-ENGLISH

CP: SPAIN

AB: The last two cases of Ellis van Creveld syndrome diagnosed in the Neonatology Service of our department are presented and the clinical and radiological features described. One of the children, the boy, was suffering from ocular malformations which are not common in this syndrome. Both have heart malformations which are frequent in this syndrome. Paradoxically the boy, who was quite below the third percentile in height, has less alterations in the long bones than did the baby girl, who was within the normal height range. Attention is called to the lack of adipose panniculus in the boy, but the girl's weight is within the normal limits. Both died because of the heart anomalities with accompanying respiratory distress.

MESH: Ellis-Van-Creveld-Syndrome-pathology; Ellis-Van-Creveld-Syndrome-radiography; English-Abstract; Heart-Defects,-Congenital-pathology; Infant,-Newborn; Prognosis-; Respiratory-Distress-Syndrome-etiology

MESH: *Ellis-Van-Creveld-Syndrome

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 90379590

UD: 9012

MEDLINE EXPRESS (R) 1990 19 of 24

TI: Ellis-Van Creveld syndrome: description of four cases. Orthopaedic aspects.

AU: Pinelli-G; Cottafava-F; Senes-FM; Becchetti-S; Cosso-D; Costa-M

AD: 1. Divisione Ortopedia e Traumatologia, Istututo G. Gaslini, Genova.

SO: Ital-J-Orthop-Traumatol. 1990 Mar; 16(1): 113-21

ISSN: 0390-5489

PY: 1990

LA: ENGLISH

CP: AUSTRIA

AB: Four cases of Ellis-Van Creveld syndrome are reported in which three were in the same family. The clinical and radiological findings were characteristic of the traditional features of the disease. The authors discuss the role of the orthopaedic surgeon in correcting the skeletal deformities.

MESH: Adolescence-; Child-; Dwarfism-radiography; Ellis-Van-Creveld-Syndrome-surgery; Scoliosis-radiography; Tooth-Abnormalities-radiography

MESH: *Ellis-Van-Creveld-Syndrome-radiography

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 90337730

UD: 9011

MEDLINE EXPRESS (R) 1990 20 of 24

TI: Ellis-van creveld syndrome, Jeune syndrome, and renal-hepatic-pancreatic dysplasia: separate entities or disease spectrum?

AU: Brueton-LA; Dillon-MJ; Winter-RM

AD: Kennedy Galton Centre, Northwick Park Hospital, Harrow, Middlesex.

SO: J-Med-Genet. 1990 Apr; 27(4): 252-5

ISSN: 0022-2593

PY: 1990

LA: ENGLISH

CP: ENGLAND

AB: We describe two children with multiple abnormalities, neither of whom fits neatly into a classical diagnostic category, but who show overlapping features of Ellis-van Creveld syndrome, Jeune syndrome, and renal-hepatic-pancreatic dysplasia. It seems possible that these three entities form part of a disease spectrum rather than being distinct conditions.

MESH: Hand-radiography; Infant,-Newborn; Kidney-abnormalities; Liver-abnormalities; Pancreas-abnormalities; Pelvic-Bones-radiography; Thoracic-Radiography

MESH: *Ellis-Van-Creveld-Syndrome-diagnosis; *Pelvic-Bones-abnormalities; *Ribs-abnormalities; *Situs-Inversus-diagnosis

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 90218961

UD: 9007

MEDLINE EXPRESS (R) 1/96-9/96 21 of 24

TI: Short rib-dysplasia group (with/without polydactyly): report of a patient suggesting the existence of a continuous spectrum.

AU: Franceschini-P; Guala-A; Vardeu-MP; Signorile-F; Franceschini-D; Bolgiani-MP

AD: Istituto di Discipline Pediatriche, Servizio di Genetica Clinica, Chivasso, Italy.

SO: Am-J-Med-Genet. 1995 Nov 20; 59(3): 359-64

ISSN: 0148-7299

PY: 1995

LA: ENGLISH

CP: UNITED-STATES

AB: We report on a patient with manifestations typical of Mohr syndrome and of the short rib (polydactyly) syndromes (SR(P)S) Majewski, Verma-Naumoff, Beemer, and Jeune. It seems possible that the different types of SR(P) syndromes, rather than being distinct conditions, are part of a large disease spectrum. The frequent overlap between orofaciodigital syndromes and SR(P) syndromes may be interpreted as the outcome of deletions of different size within the same chromosome region.

MESH: Abnormalities,-Multiple-pathology; Ellis-Van-Creveld-Syndrome-classification; Ellis-Van-Creveld-Syndrome-pathology; Fatal-Outcome; Infant,-Newborn; Orofaciodigital-Syndromes-classification; Sequence-Deletion; Short-Rib-Polydactyly-Syndrome-classification; Syndrome-

MESH: *Abnormalities,-Multiple-classification; *Chromosomes,-Human,-Pair-17-genetics; *Orofaciodigital-Syndromes-pathology; *Short-Rib-Polydactyly-Syndrome-pathology

TG: Case-Report; Human; Male

PT: JOURNAL-ARTICLE

AN: 96162321

UD: 9606

MEDLINE EXPRESS (R) 1/96-9/96 22 of 24

TI: Atrioventricular septal defect and type A postaxial polydactyly without other major associated anomalies: a specific association.

AU: Levin-SE; Dansky-R; Milner-S; Benatar-A; Govendrageloo-K; du-Plessis-J

AD: Department of Pediatrics, Johannesburg Hospital, University of the Witwatersrand, South Africa.

SO: Pediatr-Cardiol. 1995 Sep-Oct; 16(5): 242-6

ISSN: 0172-0643

PY: 1995

LA: ENGLISH

CP: UNITED-STATES

AB: Four children are described, (three black and one white, two boys and two girls) with type A postaxial polydactyly. All four of them, in addition, had either a partial or complete atrioventricular septal defect (AVSD). None of these children had associated major malformations. Minor anomalies were observed (e.g., two patients with hypersegmentation of the sternal segments, one patient with undescended testes, one patient with hypoplastic lumbar vertebra, and one patient with a degree of craniofacial abnormality). Chromosome analysis was carried out for three of the four patients, and was normal in all of them. It is suggested that there is a specific association between type A postaxial polydactyly and the AVSD found in each of these patients. This picture does not conform to, but bears some resemblance to, the Ellis-van Creveld syndrome.

MESH: Child-; Diseases-in-Twins-genetics; Ellis-Van-Creveld-Syndrome-diagnosis; Ellis-Van-Creveld-Syndrome-surgery; Heart-Septal-Defects-diagnosis; Heart-Septal-Defects-surgery; Infant-; Karyotyping-; Polydactyly-diagnosis

MESH: *Ellis-Van-Creveld-Syndrome-genetics; *Heart-Septal-Defects-genetics; *Polydactyly-genetics

TG: Case-Report; Female; Human; Male

PT: JOURNAL-ARTICLE

AN: 96030205

UD: 9603

MEDLINE EXPRESS (R) 1/96-9/96 23 of 24

TI: [The Ellis-van Creveld syndrome. A case report]

TO: Sindrome di Ellis-van Creveld. Descrizione di un caso.

AU: Gambardella-A; Cusati-B; Rotondo-A

AD: Facolta di Medicina e Chirurgia, Istituto di Scienze Radiologiche, Universita degli Studie Federico II, Napoli.

SO: Radiol-Med-Torino. 1995 Sep; 90(3): 311-3

ISSN: 0033-8362

PY: 1995

LA: ITALIAN; NON-ENGLISH

CP: ITALY

MESH: Bone-and-Bones-radiography; Child-

MESH: *Ellis-Van-Creveld-Syndrome-radiography

TG: Case-Report; Female; Human

PT: JOURNAL-ARTICLE; REVIEW; REVIEW-OF-REPORTED-CASES

AN: 96096838

UD: 9603

MEDLINE EXPRESS (R) 1/96-9/96 24 of 24

TI: [Value of echocardiography in Ellis-Van Creveld syndrome (letter)]

TO: Interet de l'echographie cardiaque dans le syndrome d'Ellis et Van Creveld.

AU: Bouguerra-L; Turki-R; Hichri-A

SO: Arch-Pediatr. 1995 Oct; 2(10): 1022

ISSN: 0929-693X

PY: 1995

LA: FRENCH; NON-ENGLISH

CP: FRANCE

MESH: Echocardiography-; Infant-

MESH: *Ellis-Van-Creveld-Syndrome-ultrasonography

TG: Case-Report; Female; Human

PT: LETTER

AN: 96099592

UD: 9603


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