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Authors NAM Bemelmans,
MAD Tilanus, MHM Cuypers, AJLG Pinckers
Title Pattern-reversal visual evoked potentials in patients with epiretinal
membrane
Full source American Journal of Ophthalmology, 1997, Vol 123, Iss 1, pp
97-102
KeyWords Plus MACULAR PUCKER; CHECK SIZE; EYES; AGE
TGA/Book No. WB822
Discipline Medical Research, Organs & Systems
Document type Article
Language English
Address Bemelmans NAM, Univ Nijmegen Hosp, Inst Ophthalmol, POB 9101, NL-6500
HB Nijmegen, NETHERLANDS
ISBN/ISSN 0002-9394
Publisher Ophthalmic Publ Co, 77 West Wacker Dr, Ste 660, Chicago, IL 60601
Abstract PURPOSE: To determine the extent of pattern-reversal visual evoked potential parameter alteration by epiretinal membranes and to investigate the use of pattern-reversal visual evoked potential in the estimation of macular function in eyes with epiretinal membrane and in the fellow eyes.
METHODS: In both eyes of 162 patients with epiretinal membrane, 92 of primary and 70 of: secondary origin, pattern-reversal visual evoked potentials were recorded. Check sizes of 17', 10', and 7' (minutes of arc) were used. Parameters investigated were N80 and P100 latencies and P100 amplitude.
RESULTS: No significant difference was detected between eyes with epiretinal membrane of primary and secondary origin regarding visual acuity and the pattern-reversal visual evoked potential parameters for the different check sizes. Compared with the fellow eyes, the eyes with epiretinal membrane had a significantly reduced visual acuity, prolonged N80 and P100 latencies, and a reduced P100 amplitude for the different check sizes. Compared with a separate control group (N = 20) with patients 50 to 59 years old, eyes with epiretinal membrane (N = 9) showed the same features as in the total group, but only for the 17' and 10' check sizes. The fellow eyes (N = 9) showed a significant reduction of the P100 amplitude (P < .05) for the pattern sizes of 17' and 10', but no difference in visual acuity or pattern-reversal visual evoked potential latency was found.
CONCLUSIONS: In eyes with epiretinal membrane, pattern-reversal visual evoked potential latencies are prolonged, and amplitude is reduced. Relationships between clinical parameters and pattern reversal visual evoked potential parameters require further study.
Authors JR Wilkins, CA Puliafito, MR Hee, JS Duker, E Reichel, JG Coker, JS Schuman, EA Swanson, JG Fujimoto
Title Characterization of epiretinal membranes using optical coherence tomography
Full source Ophthalmology, 1996, Vol 103, Iss 12, pp 2142-2151
KeyWords Plus PROGNOSTIC FACTORS; MACULAR PUCKER; IN-VIVO; REFLECTOMETRY;
VITRECTOMY; EDEMA; EYES
TGA/Book No. WB759
Discipline Medical Research, Organs & Systems
Document type Article
Language English
Address Puliafito CA, Tufts Univ, New England Med Ctr, Sch Med, 750 Washington
St, Box 450, Boston,MA 02111 USA
ISBN/ISSN 0161-6420
Publisher Lippincott-Raven Publ, 227 East Washington Sq, Philadelphia, PA
19106
Abstract Objective: To evaluate optical coherence tomography (OCT)la novel noncontact and noninvasive imaging technique, for the diagnosis and quantitative characterization of epiretinal membranes.
Methods: Optical coherence tomography is similar to an ultrasound B-scan, except that light rather than sound is used, which enables higher resolution, Over a 2-year period, OCT was used to examine 186 eyes of 160 patients who had a diagnosis of an epiretinal membrane, Optical coherence tomograms were correlated with visual acuity, slit-lamp biomicroscopy, fluorescein angiography, and fundus photography,
Results: Based on OCT, the epiretinal membrane was clearly separated from the retina with focal points of attachment in 49 eyes and globally adherent (no observed separation) in 125 eyes. Globally adherent membranes were associated with the following features: macular pseudohole (32 eyes), a difference in optical reflectivity between the membrane and retina (65 eyes), and/or a visible membrane left: or edge (92 eyes). The membrane was undetectable on OCT in 12 eyes, The membrane thickness (mean +/- standard deviation) was 61 +/- 28 mu m in the 169 eyes in which the thickness could be measured with OCT, Mean central macular thickness measured with OCT correlated with visual acuity (R(2) = 0.73),
Conclusion: Optical coherence tomography was able to provide a structural assessment of the macula that was useful in the preoperative and postoperative evaluation of epiretinal membrane surgery, Quantitative measurements and the assessment oi membrane adherence with OCT may be useful in characterizing the surgical prognosis of eyes with an epiretinal membrane.