INPUT TO THE HUMAN BRAIN, Part 1*

Introduction to Somesthesia

-- a self-paced audio-tutorial on the neuroanatomy of the general senses**

Paul Pietsch, PhD,
Professor Emeritus,

School of Optometry
Indiana University

Web Contact pietsch@indiana.edu

SOUND CONTROL

{90-min tape}
Before you mash the tape button Doc, here are a few "suggestions."
  • First off, the most important part of the lesson uses slides in a carousel you probably don't have. But don't get a case of the uptights!
    We've taken those same slides, given them the same numbers as on the tape and put them right here for you. AND we've given you a "slide control panel" -- where the numbers to click match those they guy on the tape will be tell you to go and get.
  • You won't need the sheep brains you'll hear about. (Go to a French restaurant if that talk makes you hungry.)
  • Pictures will substitute for the human brain slices the tape also mentions. They're interesting, but optional.
  • There's a diagram of the Somesthetic System below to compensate for when the tape talks about a drawing in Netter.
  • And we have some pictures to help you form a 3-D concept of the caudate nucleus.
  • Also among the pictures is a diagram of the plan of the Trigeminal or Vth cranial nerve. The trigeminal does for the head what spinal nerves do for the rest of the body.
  • Because you probably don't carry a copy of Truex and Carpenter (T & C) around in your back pack, and thus can't use the atlas referred to on the tape, we've put labels on the slides you'll be working with. If you run across those labels during a preview, don't panic. We'll get to them if they're important. If not, "don't worry about it already," as inhabitants are prone to say on the small island off the east coast of North America known as Manhattan.

Slide Control Panel

They're in descending order here because that's how the man on the tape takes them up.
There is a slide 17 even though you'll hear otherwise -- but still no slide 08.
To get back to "suggestions," click here!

SOMESTHETIC PATHWAYSTo get back to "suggestions," click here!
Based on the underlying anatomy, we can think of the the general sensations as falling to into two main categories, with markedly different courses through the spinal cord:
  1. "Dorsal (posterior) Division"
    • tactile discrimination (smart touch)
    • deep sensations (from tendons and joints),
    • proprioception (feedback from sensors in the muscles called muscle spindles)
  2. "Ventral (anterior)-Lateral Division"
    • pain
    • temperature
    • light touch (e. g., itch, tickles, libidinous sensations)
The two systems part company in the spinal cord but reunite in the upper brainstem in a final common pathway, the medical lemniscus.

The medial lemniscus terminates in the thalamus. Axons from the thalamus pass though the internal capsule and white matter of the parietal lobe to relay the somesthetic signals to the postcentral gyrus, -- the primary sensory cortex.

The neuronal cell bodies of both sets occupy the dorsal (posterior) root ganglia (in the head, the trigeminal nerve's ganglion -- semilunar g. -- serves the same purpose). The neurons of the sensory ganglia are so-called bipolar cells, with one fiber attached to the sense organ in the periphery and the other entering the spinal cord (or brainstem up in the head).

Upon penetrating the spinal cord, the incoming fibers give off branches for local (or spinal or bulbar) reflexes.
The main trunk of the fibers serving the dorsal division enter and form the bulik of the dorsal part of the spinal cord (the dorsal funiculus); uncrossed, these fibers proceed virtually straight up the spinal cord to the medulla before synapsing in the nucleus gracilis or nucleus cuneatus). [The tracts formed by these fibers are called the fasciculus (or tractus) gracilis and cuneatus. Gracilis serves the lower and cuneatus the parts of the body.]
Axons from the cuneate and gracile nuclei arc ventrally in the medulla, as the internal arcuate fibers; they cross to the opposite side of the brainstem as the decussation of the medial lemniscus.
The medial lemniscus proceeds up to and terminates in the thalamus. Fibers from cells in the thalamus pass through the internal capsule, into the white matter of the parietal lobe and terminte in the cortex of the postcentral gyrus.

Senstions of the somesthetic system's ventral division travel on fibers that synapse soon after entering the spinal cord -- on cells of the dorsal gray horn. Fibers of dorsal horn cells cross to the other side of the cord (in the anterior commissure) and form tracts in the ventral (anterior) and ventro-lateral portions of the of the cord: the spino-thalamic tracts. The spinothalamic tracts join the medial lemniscus in the midbrain and thereafter follow the same overall pathway as the somesthetic system in general. (See also discussion relative to the trigeminal nerve).

LATERAL DISSECTION OF THE INTERNAL CAPSULE
Here, the side of the cerebrum and lenticular nucleus have been dissected away to expose the lateral aspect of the internal capsule:
  • anterior limb -- AL
  • genu --G
  • posterior limb -- PL
  • the untagged arrow points toward what shows of the brain stem
The thalamus lies on the other side of the posterior limb of the internal capsule (PL). Somesthetic pathways from the thalamus reach the postcenral gyrus (partially dissected away here) via the internal capsule. Back to narrative on somesthetic pathways!