Indiana University Research & Creative Activity

25th Anniversary

Volume XXV Number 1
Fall 2002

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Just as molecular biology techniques are helping reunify biology, collaboration is at the heart of the Indiana Genomics Initiative (INGEN), funded by a $105 million, three-year grant from Lilly Endowment.

INGEN's goal is to build tomorrow's medicine and health care on the foundation provided by the sequencing of the human genome, as well as the genomes of other species.

Six programs make up INGEN: genomics, bioethics, medical informatics, bioinformatics, education, and training. These programs are supported by nine cores: animals, cell and protein expression, information technology, integrated microscopy, in vivo imaging, genotyping and gene expression, human expression, proteomics, and technology transfer.

INGEN brings together scientists from the Indiana University School of Medicine in Indianapolis and from science departments at IU Bloomington in new ways. Last spring, for example, IUB Distinguished Professor of biology Thomas Kaufman told a Medical School audience about the opportunities his specialty--Drosophila, the fruit fly--holds for researchers studying human disease. It was the first of a series of lectures planned to let folks on both campuses learn more about what their counterparts are doing.

INGEN's proteomics (the comprehensive analysis of large sets of proteins) core explicitly includes scientists from both Indianapolis and Bloomington. Chemistry faculty members David E. Clemmer, Milos V. Novotny, and James P. Reilly comprise the active faculty of the Bloomington proteomics unit, focusing on new equipment for proteomics research. Proteomics core faculty from the School of Medicine--John Hawes, Mu Wang, Frank Witzmann, and Robert Harris--are developing proteomics applications and helping faculty use the new resources provided by INGEN.

In its first 18 months, INGEN has contributed to a substantial buildup of research infrastructure, both human and equipment. Grant applications--and grants--have followed. The next 18 months should see the first early research results.

For more information, see