Richard DiMarchi Research Group

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Publications

1.         DiMarchi, RD; Wang, CC; Hemenway, JB; Gurd, FR Complete amino acid sequence of the major component myoglobin of finback whale (BalaenopteraPhysalus).  Biochemistry (1978), 17(10), 1968-70.  Journal Code:  0370623.  ISSN: 0006-2960. PubMed ID 656375 AN 1978 187212 Medline

2.         DiMarchi, Richard D; Garner, William H; Wang, Chi-Chin; Hanania, George I.H.; Gurd, Frank, RN; Characterization of the reaction of methyl acetimidate with sperm whale myoglobin. Biochemstry (1978), 17(14), 2822-9.  CODEN: BICHAW ISSN: 0006-2960. CAN 89:18699 AN 1978:418699 CAPLUS

3.         DiMarchi, Richard Dennis. Semisynthetic studies of the amino-terminal region of sperm whale myoglobin and the complete amino acid sequence of the major component myoglobin of the finback whale (Balaenoptera physalus). (1979), 281 pp.  CAN 91:170247  AN 1979:570247    CAPLUS

4.         Gurd, Frank R. N.; Garner, William H.; DiMarchi, Richard D.; Wang, Chi-Chin.   Production of semisynthetic myoglobin by stepwise fragment condensation.  Pept., Proc. Am. Pept. Symp., 5th  (1977), 480-3.  CODEN: 37OBAT  CAN 89:6544  AN 1978:406544    CAPLUS

5.         DiMarchi, Richard D.; Garner, William H.; Wang, Chi-Chin; Gurd, Frank R. N.   Semisynthetic studies at the amino-terminal region of sperm whale myoglobin.    Semisynth. Pept. Proteins, Pap. Int. Meet. Protein Semisynth.  (1978),  Meeting Date 1977, 45-57.  CODEN: 39MMAW  CAN 90:204486  AN 1979:204486    CAPLUS

6.         Wang, Chi-Chin; DiMarchi, Richard; Gurd, Frank R. N.   Replacement of the N-terminal tetradecapeptide sequence of sperm whale myoglobin.    Semisynth. Pept. Proteins, Pap. Int. Meet. Protein Semisynth.  (1978),  Meeting Date 1977,     59-69.  CODEN: 39MMAW  CAN 90:138195  AN 1979:138195    CAPLUS

7.         DiMarchi, Richard D.; Neireiter, George W.; Garner, William H.; Gurd, Frank R. N.   Myoglobin semisynthesis:  removal of the amino-terminal valine of sperm whale myoglobin and its subsequent reincorporation. Biochemistry  (1979),  18(14),  3101-9.  CODEN: BICHAW  ISSN:0006-2960.  CAN 91:74893  AN 1979:474893    CAPLUS

8.         Neireiter, G. W.; DiMarchi, R. D.; Gurd, F. R. N.   NH2-Terminal myoglobin semisynthesis.    Pept., Struct. Biol. Funct., Proc. Am. Pept. Symp., 6th  (1979),  621-4.  CODEN: 44LVAU  CAN 94:157235  AN 1981:157235    CAPLUS

9.         DiMarchi, Richard D.; Neireiter, George W.; Heath, William F.; Gurd, Frank R. N.   Structural significance of the amino-terminal residues of sperm whale myoglobin. Biochemistry  (1980),  19(11),  2454-65.  CODEN: BICHAW  ISSN:0006-2960.  CAN 93:20994  AN 1980:420994    CAPLUS

10.       Tam, James P.; DiMarchi, Richard D.; Merrifield, R. B.   Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis. International Journal of Peptide & Protein Research  (1980),  16(5),  412-25.  CODEN: IJPPC3  ISSN:0367-8377.  CAN 94:175508  AN 1981:175508    CAPLUS

11.       Tam, James P.; DiMarchi, Richard D.; Merrifield, R. B.   Design and synthesis of a multidetachable benzhydrylamine resin for solid phase peptide synthesis.    Tetrahedron Letters  (1981),  22(30),  2851-4.  CODEN: TELEAY  ISSN:0040-4039.  CAN 95:204411  AN 1981:604411    CAPLUS

12.       DiMarchi R D; Tam J P; Kent S B; Merrifield R B   Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling.    International journal of peptide and protein research  (1982),  19(1),  88-93.  Journal code: 0330420.  ISSN:0367-8377.  PubMed ID 7118385 AN 83006105    MEDLINE

13.       DiMarchi, Richard D.; Tam, James P.; Merrifield, R. B.   Solid phase synthesis of the protected 43-55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid.    International Journal of Peptide & Protein Research  (1982),  19(3),  270-9.  CODEN: IJPPC3  ISSN:0367-8377.  CAN 97:24225  AN 1982:424225    CAPLUS

14.       Voss, Christoph; DiMarchi, Richard; Whitney, Donald B.; Tjoeng, Foe Siong; Merrifield, R. B.; Tam, James P.   Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports.    International Journal of Peptide & Protein Research  (1983),  22(2),  204-13.  CODEN: IJPPC3  ISSN:0367-8377.  CAN 100:51962  AN 1984:51962    CAPLUS

15.       DiMarchi, Richard; Brooke, Gerald; Gale, Charles; Cracknell, Victor; Doel, Timothy; Mowat, Noel.   Protection of cattle against foot-and-mouth disease by a synthetic peptide.    Science (Washington, DC, United States)  (1986),  232(4750),  639-41.  CODEN: SCIEAS  ISSN:0036-8075.  CAN 104:223063  AN 1986:223063    CAPLUS

16.       Wagner, J. F., Anderson, D. B., Cain, T. D., DiMarchi, R. D., Monrey, D. H., McGuffey, R. K., and Wray, M. I. (1987).  Effect of Continuously Infused Human Pancreatic Growth Hormone-Releasing Factor on Plasma Growth Hormone Concentration in the Wether Lamb.  J. Animal Science 221, 89-97.

17.       Johnson, B. G., DiMarchi, R. D., Smith, M. C., and Mendelsohn, L. G. (1987).  Stimulation of Aminoisobutyrate Transport and Protein Synthesis in Human Fibroblasts by the Insulin-Like Growth Factors:  Measurement of the Biopotencies of Recombinant Human Peptides.  J. of Cell Biol. 104, 109-114.

18.       Doel, T. R.; Gale, C.; Brooke, G.; DiMarchi, R..   Immunization against foot-and-mouth disease with synthetic peptides representing the C-terminal region of VP1.    Journal of General Virology  (1988),  69(9),  2403-6.  CODEN: JGVIAY  ISSN:0022-1317.  CAN 109:168519  AN 1988:568519    CAPLUS

19.       DiMarchi, R.; Osborne, E.; Roberts, E.; Slieker, L.   Chemical synthesis of human epidermal growth factor (EGF) and human type a  transforming growth factor (TGFa ).    Pept.:  Chem. Biol., Proc. Am. Pept. Symp. 10th  (1988),  Meeting Date 1987,     202-3.  CODEN: 56MDA6  CAN 112:7906  AN 1990:7906    CAPLUS

20.       DiMarchi, R.; Brooke, G.; Gale, C.; Doel, T.   Structure-function relationship in protection against foot and mouth disease (FMD) by a synthetic peptide.    Pept.:  Chem. Biol., Proc. Am. Pept. Symp. 10th  (1988),  Meeting Date 1987,     531-3.  CODEN: 56MDA6  CAN 111:55346  AN 1989:455346    CAPLUS

21        DiMarchi, Richard; Long, Harlan; Epp, Janet; Schoner, Brigitte; Belagaje, Rama.   Synthesis of insulin-like growth factor I through recombinant DNA techniques and selective chemical cleavage at tryptophan.    UCLA Symposia on Molecular and Cellular Biology, New Series  (1989),  86(Synth. Pept.),  283-94.  CODEN: USMBD6  ISSN:0735-9543.  CAN 110:208830  AN 1989:208830    CAPLUS

22.       Thakker, Jay K.; DiMarchi, Richard; MacDonald, Kenneth; Caro, Jose F.   Effect of insulin and insulin-like growth factors I and II on phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate breakdown in liver from humans with and without type II diabetes.    Journal of Biological Chemistry  (1989),  264(13),  7169-75.  CODEN: JBCHA3  ISSN:0021-9258.  CAN 110:225833  AN 1989:225833    CAPLUS

23.       Sinha, Madhur K.; Buchanan, Cresada; Leggett, Nancy; Martin, Lourdes; Khazanie, Prabhaker G.; DiMarchi, Richard; Pories, Walter J.; Caro, Jose F.   Mechanism of IGF-I-stimulated glucose transport in human adipocytes.  Demonstration of specific IGF-I receptors not involved in stimulation of glucose transport.    Diabetes  (1989),  38(10),  1217-25.  CODEN: DIAEAZ  ISSN:0012-1797.  CAN 111:209673  AN 1989:609673    CAPLUS

24.       Schalch, Don S.; Yang, Huan; Ney, Denise M.; DiMarchi, Richard D..   Infusion of human insulin-like growth factor I (IGF-I) into malnourished rats reduces hepatic IGF-I mRNA abundance.    Biochemical and Biophysical Research Communications  (1989),  160(2),  795-800.  CODEN: BBRCA9  ISSN:0006-291X.  CAN 110:226096  AN 1989:226096    CAPLUS

25.       Gale, Charles; Doel, Tim; Brooke, Gerry; White, Don; Mulcahy, Grace; DiMarchi, Richard.   Protection induced by synthetic peptides corresponding to three serotypes in foot and mouth disease virus.    Advances in Experimental Medicine and Biology  (1989),  251(Immunobiol. Proteins Pept. 5),  161-7.  CODEN: AEMBAP  ISSN:0065-2598.  CAN 113:56868  AN 1990:456868    CAPLUS

26.       DiMarchi, Richard Dennis; Long, Harlan Beall Reduction of methionine sulfoxide residues in peptides and proteins.  Ger. Offen. (1989), 6 pp. CODEN: GWXXBX DE 3828287 A1 19890309 CAN 111:97728 AN 1989:497728 CAPLUS

27.       Sinha, Madhur K.; Buchanan, Cresada; Raineri-Maldonado, Carla; Khazanie, Prabhaker; Atkinson, Samuel; DiMarchi, Richard; Caro, Jose F.   IGF-II receptors and IGF-II-stimulated glucose transport in human fat cells.    American Journal of Physiology  (1990),  258(3, Pt. 1),  E534-E542.  CODEN: AJPHAP  ISSN:0002-9513.  CAN 112:192651  AN 1990:192651    CAPLUS

28.       Doel, T. R.; Gale, C.; Do Amaral, C. M. C. F.; Mulcahy, G.; DiMarchi, R..   Heterotypic protection induced by synthetic peptides corresponding to three serotypes of foot-and-mouth disease virus.    Journal of Virology  (1990),  64(5),  2260-4.  CODEN: JOVIAM  ISSN:0022-538X.  CAN 113:4279  AN 1990:404279    CAPLUS

29.       Mulcahy, G., Gale, C., Robertson, P., Lyisan, S., DiMarchi, R. D., and Doel, T. R. (1990).  Isotype Responses of Infected, Virus-Vaccinated and Peptide-Vaccinated Cattle to FMDV.  Vaccine 8, 249-256. CODEN: JOVIAM  ISSN:0022-538X.  CAN 113:4279  AN 1990:404279    CAPLUS

30.       Heiman, M. L.; Surface, P. L.; Mowrey, D. H.; DiMarchi, R. D..   Sexual dimorphic porcine pituitary response to growth hormone-releasing hormone.    Domestic Animal Endocrinology  (1990),  7(2),  273-6.  CODEN: DANEEE  ISSN:0739-7240.  CAN 113:126752  AN 1990:526752    CAPLUS

31.       Flynn, J. N.; Harkiss, G. D.; Doel, T.; DiMarchi, R..   Analysis of immune responses in the sheep to synthetic peptides of foot-and-mouth disease virus using ovine polyclonal and monoclonal antibodies.    Immunology  (1990),  69(1),  1-7.  CODEN: IMMUAM  ISSN:0019-2805.  CAN 112:196296  AN 1990:196296    CAPLUS

32.       Dohm, G. L., Elton, C. W., Raju, M. S., Mooney, N. D., DiMarchi, R. D., Pories, W. I, Flickinger, E. G., Atkinson, S. M., and Caro, J. F. (1990).  IGF-I Stimulated Glucose Transport in Human Skeletal Muscle:  IGF-I   Resistance in Obesity and NIDDM.  Diabetes, 39, (9) 1028-1032.

33.       Mulcahy, G., Pullen, L. A., Gale, C., DiMarchi, R. D., and Doel, T.R. (1990). A Mouse Protection Test as a Predictor of the Protective Capacity of Synthetic FMDV Vaccines.  Vaccine 9, 19-24.

34.       DiMarchi, R. D.; Long, H. B.; Kroeff, E. P.; Chance, R. E.   Utilization of analytical reversed-phase HPLC in biosynthetic insulin production.    High Perform. Liq. Chromatogr. Biotechnol.  (1990),     181-9.  CODEN: 56YYAR  CAN 115:127055  AN 1991:527055    CAPLUS

35.       DiMarchi, R. D.; Long, H.; Epp, J.; Schoner, B.; Belagaje, R.   Biosynthesis and characterization of insulin-like growth factor I (IGF-I).    Pept.:  Chem., Struct. Biol., Proc. Am. Pept. Symp., 11th  (1990),  Meeting Date 1989,     99-100.  CODEN: 56XTA7  CAN 114:222045  AN 1991:222045    CAPLUS

36.       DiMarchi, R. D.; Brooke, G. S.; Johnson, M.; Long, H. B.; Mayer, J. P.   Chromatography viewed as an integral part of successful solid-phase peptide synthesis.    Pept.:  Chem., Struct. Biol., Proc. Am. Pept. Symp., 11th  (1990),  Meeting Date 1989,     229-30.  CODEN: 56XTA7  CAN 115:29871  AN 1991:429871    CAPLUS

37.       DiMarchi, R. D., Mulcahy, G., DoAmaral, C. M. C. F., Brooke, G., Gale, C., and Doel, T.  Heterotypic Protection Induced by Synthetic Peptides Corresponding to Three Serotypes of Foot-and-Mouth Disease Virus.  Pept.:  Chem., Struct. Biol., Proc. Am. Pept. Symp., 11th  (1990),  Meeting Date 1989,     275-7.  CODEN: 56XTA7  CAN 114:62741  AN 1991:62741    CAPLUS

38.       Mayer, J. P.; Brooke, G. S.; DiMarchi, R. D..   Chemical synthesis of the A-chain of human insulin.    Pept.:  Chem., Struct. Biol., Proc. Am. Pept. Symp., 11th  (1990),  Meeting Date 1989,     1061-2.  CODEN: 56XTA7  CAN 114:62741  AN 1991:62741    CAPLUS

39.       Collen, Trevor; DiMarchi, Richard; Doel, Timothy R.   A T cell epitope in VP1 of foot-and-mouth disease virus is immunodominant for vaccinated cattle.   Journal of Immunology  (1991),  146(2),  749-55.  CODEN: JOIMA3  ISSN:0022-1767.  CAN 114:119847  AN 1991:119847    CAPLUS

40.       Rossetti, Luciano; Frontoni, Simona; DiMarchi, Richard; DeFronzo, Ralph A.; Giaccari, Andrea.   Metabolic effects of IGF-I in diabetic rats.    Diabetes  (1991),  40(4),  444-8.  CODEN: DIAEAZ  ISSN:0012-1797.  CAN 115:133199  AN 1991:533199    CAPLUS

41.       Steward M W; Stanley C M; DiMarchi R; Mulcahy G; Doel T R   High-affinity antibody induced by immunization with a synthetic peptide is associated with protection of cattle against foot-and-mouth disease.    Immunology  (1991),  72(1),  99-103.  Journal code: 0374672.  ISSN:0019-2805.  PubMed ID 1847695 AN 91147152    MEDLINE

42.       Burguera B; Frank B H; DiMarchi R; Long S; Caro J F   The interaction of proinsulin with the insulin-like growth factor-I receptor in human liver, muscle, and adipose tissue.    The Journal of clinical endocrinology and metabolism  (1991),  72(6),  1238-41.  Journal code: 0375362.  ISSN:0021-972X.  PubMed ID 1851182 AN 91225197    MEDLINE

43.       Broderick, Carol L.; Brooke, Gerald S.; DiMarchi, Richard D.; Gold, Gerald.   Human and rat amylin have no effects on insulin secretion in isolated rat pancreatic islets.    Biochemical and Biophysical Research Communications  (1991),  177(3),  932-8.  CODEN: BBRCA9  ISSN:0006-291X.  CAN 115:65182  AN 1991:465182    CAPLUS

44.       Kit, Malon; Kit, Saul; Little, Sheila; DiMarchi, Richard; Gale, Charles.   Infectious bovine rhinotracheitis virus vector that expresses foot-and-mouth disease virus epitopes on the surface of viral particles and virus-infected cells.    Vaccines 91:  Mod. Approaches New Vaccines Incl. Prev. AIDS, [Annu. Meet. Mod. Approaches New Vaccines], 8th  (1991),  Meeting Date 1990,     327-31.  CODEN: 57HGAV  CAN 115:277336  AN 1991:677336   

45.       Bodkin, N. L.; Sportsman, R.; DiMarchi, R. D.; Hansen, B. C.   Insulin-like growth factor-I in non-insulin-dependent diabetic monkeys:  basal plasma concentrations and metabolic effects of exogenously administered biosynthetic hormone.    Metabolism, Clinical and Experimental  (1991),  40(11),  1131-7.  CODEN: METAAJ  ISSN:0026-0495.  CAN 115:199129  AN 1991:599129    CAPLUS

46.       Burguera, Bartolome; Frank, Bruce H.; DiMarchi, Richard; Long, Stuart; Caro, Jose F.   The interaction of proinsulin with the insulin-like growth factor-I receptor in human liver, muscle, and adipose tissue.    Journal of Clinical Endocrinology and Metabolism  (1991),  27(6),  1238-41.  CODEN: JCEMAZ  ISSN:0021-972X.  CAN 115:151186  AN 1991:551186    CAPLUS

47.       Kit, Malon; Kit, Saul; Little, Sheila P.; DiMarchi, Richard D.; Gale, Charles.   Bovine herpesvirus-1 (infectious bovine rhinotracheitis virus)-based viral vector which expresses foot-and-mouth disease epitopes.    Vaccine  (1991),  9(8),  564-72.  CODEN: VACCDE  ISSN:0264-410X.  CAN 116:122150  AN 1992:122150    CAPLUS

48.       Kit, S.; Kit, Malcon; DiMarchi, R. D.; Little, Sheila P.; Gale, C.   Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles.    Archives of Virology  (1991),  120(1-2),  1-17.  CODEN: ARVIDF  ISSN:0304-8608.  CAN 116:19397  AN 1992:19397    CAPLUS

49.       Kit, Saul; Kit, Malon; DiMarchi, Richard; Little, Sheila; Gale, Charles.   Modified-live infectious bovine rhinotracheitis virus (IBRV) vaccine expressing foot-and-mouth disease virus (FMDV) capsid protein epitopes on surface of hybrid virus particles.    Advances in Experimental Medicine and Biology  (1991),  303(Immunobiol. Proteins Pept. 6),  211-20.  CODEN: AEMBAP  ISSN:0065-2598.  CAN 117:5650  AN 1992:405650    CAPLUS

50.       Owens, R. A.; Gesellchen, P. D.; Houchins, B. J.; DiMarchi, R. D..   The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures.    Biochemical and Biophysical Research Communications  (1991),  181(1),  402-8.  CODEN: BBRCA9  ISSN:0006-291X.  CAN 116:50900  AN 1992:50900    CAPLUS

51.       Kit, S., Kit, M., DiMarchi, R. D., Little, S. P., and Gale, C. (1991).  “Modified- Live Infectious Bovine Rhinotracheitis Virus (IBRV) Vaccine Expressing Foot-and-Mouth Disease Virus (FMDV) Capsid Protein Epitopes on Surface of Hybrid Virus Particles.”  Immunobiology of Proteins and Peptides VI, 211-220.

52.       Mulcahy G; Pullen L A; Gale C; DiMarchi R D; Doel T R   Mouse protection test as a predictor of the protective capacity of synthetic foot-and-mouth disease vaccines.    Vaccine  (1991),  9(1),  19-24.  Journal code: 8406899.  ISSN:0264-410X.  PubMed ID 1848960 AN 91181299    MEDLINE

53.       Mulcahy G; Reid E; DiMarchi R D; Gale C; Doel T R   Maturation of functional antibody affinity in animals immunised with synthetic foot-and-mouth disease virus.    Research in veterinary science  (1992),  52(2),  133-40.  Journal code: 0401300.  ISSN:0034-5288.  PubMed ID 1316628 AN 92262922    MEDLINE

54.       Glass, E. J.; Oliver, R. A.; Collen, T.; Doel, T. R.; DiMarchi, R.; Spooner, R. L.   MHC class II restricted recognition of FMDV peptides by bovine T cells.Immunology  (1991),  74(4),  594-9.  CODEN: IMMUAM  ISSN:0019-2805.  CAN 116:103952  AN 1992:103952    CAPLUS

55.       DiMarchi, R. D.; Mayer, J. P.; Fan, L.; Brems, D. N.; Frank, B. H.; Green, L. K.; Hoffmann, J. A.; Howey, D. C.; Long, H. B.; et al.   Synthesis of a fast-acting insulin based on structural homology with insulin-like growth factor I.    Pept.:  Chem. Biol., Proc. Am. Pept. Symp., 12th  (1992),  Meeting Date 1991,  26-8.  CODEN: 57XGA9  CAN 117:124711  AN 1992:524711    CAPLUS

56.       Heath, W. F., Belagaje, R. M., Brooke, G. S., Chance, R. E., Hoffmann, J. A.,  Long, H. B., Reams, S. G., Roundtree, C., Shaw, W. N., Slieker, L. J., Sundell, K. L., and  DiMarchi, R. D.  (1992).  (A-C-B) Human Proinsulin, A Novel Insulin Agonist and Intermediate in the Synthesis of Biosynthetic Human Insulin. Journal of Biological Chemistry, 267, 419-425

57.       Long, Harlan B.; Belagaje, Rama M.; Brooke, Gerald S.; Chance, Ronald E.; DiMarchi, Richard D.; Hoffman, James A.; Reams, Steven G.; Roundtree, Carolyn; Shaw, Walter N.; et al.   A-C-B human proinsulin:  a novel insulin agonist and intermediate in the synthesis of human insulin.    Pept.:  Chem. Biol., Proc. Am. Pept. Symp., 12th  (1992),  Meeting Date 1991,     93-4.  CODEN: 57XGA9  CAN 119:1107  AN 1993:401107    CAPLUS

58.       Smiley, David L.; Heiman, Mark L.; Tinsley, Frank C.; Wagner, Jack F.; DiMarchi, Richard D..   Chemical potentiation of growth hormone releasing hormone analogs.    Pept.:  Chem. Biol., Proc. Am. Pept. Symp., 12th  (1992),  Meeting Date 1991,     91-2.  CODEN: 57XGA9  CAN 117:124725  AN 1992:524725    CAPLUS

59.       Long, H. B.; Baker, J. C.; Belagaje, R. M.; Di Marchi, R. D.; Frank, B. H.; Green, L. K.; Hoffmann, J. A.; Muth, W. L.; Pekar, A. H.; et al.   Human insulin analogs with rapid onset and short duration of action.    Pept.:  Chem. Biol., Proc. Am. Pept. Symp., 12th  (1992),  Meeting Date 1991,     88-90.  CODEN: 57XGA9  CAN 117:124724  AN 1992:524724    CAPLUS

60.       Flynn, J. N.; Harkiss, G. D.; Moore, D.; DiMarchi, R..   Modulation of T-cell reactivity to synthetic peptide analogs of foot-and-mouth disease virus in sheep by amino acid substitutions.    Veterinary Immunology and Immunopathology  (1992),  31(3-4),  255-66.  CODEN: VIIMDS  ISSN:0165-2427.  CAN 117:109629  AN 1992:509629    CAPLUS

61.       Brems D N; Alter L A; Beckage M J; Chance R E; DiMarchi R D; Green L K; Long H B; Pekar A H; Shields J E; Frank B H   Altering the association properties of insulin by amino acid replacement.    Protein engineering  (1992),  5(6),  527-33.  Journal code: 8801484.  ISSN:0269-2139.  PubMed ID 1438163 AN 93066141    MEDLINE

62.       Doel, T. R.; Doel, C. M. F. A.; Staple, R. F.; DiMarchi, R..   Cross-reactive and serotype-specific antibodies against foot-and-mouth disease virus generated by different regions of the same synthetic peptide.    Journal of Virology  (1992),  66(4),  2187-94.  CODEN: JOVIAM  ISSN:0022-538X.  CAN 116:253663  AN 1992:253663    CAPLUS

63.       Brems, David N.; Brown, Patricia L.; Bryant, Christopher; Chance, Ronald E.; DiMarchi, Richard D.; Green, L. Kenney; Howey, Daniel C.; Long, Harian B.; Miller, Alita A.; et al.   Altering the self-association and stability of insulin by amino acid replacement.    ACS Symposium Series  (1993),  526(Protein Folding),  254-69.  CODEN: ACSMC8  ISSN:0097-6156.  CAN 119:86195  AN 1993:486195    CAPLUS


64.       Slieker, L. J.; Brooke, G. S.; Chance, R. E.; DiMarchi, R. D.; Fan, L.; Hoffman, J. A.; Howey, D. C.; Long, H.; Mayer, J.; et al.   Insulin and IGF-I analogs: Novel approaches to improved insulin pharmacokinetics.    Pept.:  Biol. Chem., Proc. Chin. Pept. Symp.  (1993),  Meeting Date 1992,     7-10.  CODEN: 59YOAI  CAN 121:27072  AN 1994:427072    CAPLUS

65.       Slieker, L. J., Brooke, G. S., Chance, R. E., Fan, L., Hoffmann, J. A.,  Howey, D. C., Long, H. B., Mayer, J., Shields, J. E., Sundell, K. L., and DiMarchi, R. D. (1993).  Insulin and IGF-I Analogs:  Novel Approaches to Improved Insulin Pharmacokinetics.  Proceedings of the Fourth Intl. Symposium on Insulin, IGFs and Their Receptors, (LeRoith, D., Raizada, M. K. Ed.), 25-32.

66.       DiMarchi, R. D.; Chance, R. E.; Long, H. B.; Shields, J. E.; Slieker, L. J.   Preparation of an insulin with improved pharmacokinetics relative to human insulin through consideration of structural homology with insulin-like growth factor I.    Hormone Research  (1994),  41(2),  93-6.  CODEN: HRMRA3  ISSN:0301-0163.  CAN 121:99972  AN 1994:499972    CAPLUS

67.       Burguera, Bartolome; Elton, Charles W.; Tapscott, Edward B.; Pories, Walter J.; Dimarchi, Richard; Sakano, Katsu-ichi; Dohm, G. Lynis.   Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor.    Biochemical Journal  (1994),  300(3),  781-5.  CODEN: BIJOAK  ISSN:0264-6021.  CAN 121:1968  AN 1994:401968    CAPLUS

68.       Burguera, B.; Elton, C. W.; Caro, J. F.; Tapscott, E. B.; Pories, W. J.; DiMarchi, R.; Sakano, K.; Dohm, G. L.   Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor. [Erratum to document cited in CA121:1968].    Biochemical Journal  (1994),  304(3),  1023.  CODEN: BIJOAK  ISSN:0264-6021.  CAN 122:307253  AN 1995:295825    CAPLUS

69.       DiMarchi, R.D. and Trautmann, M. (1996).  “Insulin Lispro: Molekularstruktur und Biologische Wirkungen.”  Diabetes und Stoffwechsel, 5, 113-116.

70.       Zhao, M.; Fan, L.; Long, H. B.; Pekar, A. H.; Slieker, L. J.; Chance, R. E.; DiMarchi, R. D..   Sequential replacement of the C-terminal residues of the human insulin B chain with alanine.    Peptides: Chemistry, Structure and Biology, Proceedings of the American Peptide Symposium, 14th, Columbus, Ohio, June 18-23, 1995  (1996),  Meeting Date 1995,     643-644.  CODEN: 63NTAF  CAN 126:42775  AN 1996:696036    CAPLUS

71.       Zhao, M.; DiMarchi, R. D..   Amino-methylene, y (CH2NH) substitution of amide bonds in the C-terminal portion of the insulin B chain.    Peptides: Chemistry, Structure and Biology, Proceedings of the American Peptide Symposium, 14th, Columbus, Ohio, June 18-23, 1995  (1996),  Meeting Date 1995,     641-642.  CODEN: 63NTAF  CAN 126:42774  AN 1996:696035    CAPLUS

72.       Smiley, D. L.; DiMarchi, R. D.; Surface, P. L.; Harris, G. C.; Heiman, M. L.   p-methylhippuric acid is a novel N-terminal Tyr replacement for growth hormone-releasing hormone.    Peptides: Chemistry, Structure and Biology, Proceedings of the American Peptide Symposium, 14th, Columbus, Ohio, June 18-23, 1995  (1996),  Meeting Date 1995,     631-632.  CODEN: 63NTAF  CAN 126:26936  AN 1996:696030    CAPLUS

73.       Anderson, J. H., Jr.; Chance, R. E.; Slieker, L. J.; Vignati, L.; DiMarchi, R. D..   Design of an optimal mealtime insulin (Lys-Pro) and its assessment in phase III clinical studies.    Peptides: Chemistry, Structure and Biology, Proceedings of the American Peptide Symposium, 14th, Columbus, Ohio, June 18-23, 1995  (1996),  Meeting Date 1995,     617-619.  CODEN: 63NTAF  CAN 126:27082  AN 1996:696024    CAPLUS

74.       Anderson, Jr., J. H., Wilke, T. S., DiMarchi, R. D., and Chance, R. E. (1966).  Insulin Analogues:  Designer Insulins with Improved Characteristics for Better Patient Care.  Diabetes News, XVII, 5-7.

75.       Radziuk J M; Davies J C; Pye W S; Shields J E; DiMarchi R D; Chance R E   Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs--LysB28ProB29-human insulin and AspB10LysB28ProB29-human insulin--assessed in a conscious pig model.    Diabetes  (1997),  46(4),  548-56.  Journal code: 0372763.  ISSN:0012-1797.  PubMed ID 9075793 AN 97230215    MEDLINE


76.       Anderson, James H., Jr.; Brunelle, Rocco L.; Koivisto, Veikko A.; Pfutzner, Andreas; Trautmann, Michael E.; Vignati, Louis; DiMarchi, Richard; The Multicenter Insulin Lispro Study Group.   Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment.    Diabetes  (1997),  46(2),  265-270.  CODEN: DIAEAZ  ISSN:0012-1797.  CAN 126:140074  AN 1997:63872    CAPLUS

77.      Anderson J H Jr; Brunelle R L; Koivisto V A; Trautmann M E; Vignati L; DiMarchi R   Improved mealtime treatment of diabetes mellitus using an insulin analogue. Multicenter Insulin Lispro Study Group.    Clinical therapeutics  (1997),  19(1),  62-72.  Journal code: 7706726.  ISSN:0149-2918.  PubMed ID 9083709 AN 97237231    MEDLINE

78.       Anderson, James H., Jr.; Brunelle, Rocco L.; Keohane, Patrick; Koivisto, Veikko A.; Trautmann, Michael E.; Vignati, Louis; DiMarchi, Richard.   Mealtime treatment with insulin analog improves postprandial hyperglycemia and hypoglycemia in patients with non-insulin-dependent diabetes mellitus.    Archives of Internal Medicine  (1997),  157(11),  1249-1255.  CODEN: AIMDAP  ISSN:0003-9926.  CAN 127:90795  AN 1997:431994    CAPLUS

79.       Slieker, L. J.; Brooke, G. S.; DiMarchi, R. D.; Flora, D. B.; Green, L. K.; Hoffmann, J. A.; Long, H. B.; Fan, L.; Schields, J. E.; Sundell, K. L.; Surface, O. L.; Chance, R. E.   Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.    Diabetologia  (1997),  40(Suppl. 2),  S54-S61.  CODEN: DBTGAJ  ISSN:0012-186X.  CAN 127:200146  AN 1997:453517    CAPLUS

80.       Radziuk, Jerry M.; Davies, Jill C.; Pye, W. Susan; Shields, James E.; DiMarchi, Richard D.; Chance, Ronald E.   Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs-LysB28ProB29-human insulin and AspB10LysB28ProB29-human insulin-assessed in a conscious pig model.   Diabetes  (1997),  46(4),  548-556.  CODEN: DIAEAZ  ISSN:0012-1797.  CAN 126:288344  AN 1997:216905    CAPLUS

81.       Ido, Y.; Vindigni, A.; Chang, K.; Stramm, L.; Chance, R.; Heath, W. F.; DiMarchi, R. D.; Di Cera, E.; Williamson, J. R.   Prevention of vascular and neural dysfunction in diabetic rats by C-peptide.    Science (Washington, D. C.)  (1997),  277(5325),  563-566.  CODEN: SCIEAS  ISSN:0036-8075.  CAN 127:200126  AN 1997:484369    CAPLUS

82.       Davidson J A; Garber A J; DiMarchi R D; Santiago J V   New advances in insulin treatment of diabetes: overcoming barriers.    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists  (1997),  3(6),  371-84.  Journal code: 9607439.  ISSN:1530-891X.  PubMed ID 15251776 AN 2005067718    MEDLINE

83.       Zhang, Faming; Basinski, Margret B.; Beals, John M.; Briggs, Stephen L.; Churgay, Lisa M.; Clawson, David K.; DiMarchi, Richard D.; Furman, Thomas C.; Hale, John E.; Hsiung, Hansen M.; Schoner, Brigitte E.; Smith, Dennis P.; Zhang, Xing Y.; Wery, Jean-Pierre; Schevitz, Richard W.   Crystal structure of the obese protein leptin-E100.    Nature (London)  (1997),  387(6629),  206-209.  CODEN: NATUAS  ISSN:0028-0836.  CAN 127:45090  AN 1997:319512    CAPLUS

84.       Chance, Ronald E.; Frank, Bruce H.; Radziuk, Jerry M.; DiMarchi, Richard D..   Discovery and development of insulin lispro.    Drugs of Today  (1998),  34(Suppl. C, Insulin Lispro),  1-9.  CODEN: MDACAP  ISSN:0025-7656.  CAN 129:170569  AN 1998:400946    CAPLUS


85.       Radziuk J; Pye S; Bradley B; Braaten J; Vignati L; Roach P; Bowsher R; DiMarchi R; Chance R   Basal activity profiles of NPH and [Nepsilon-palmitoyl Lys (B29)] human insulins in subjects with IDDM.    Diabetologia  (1998),  41(1),  116-20.  Journal code: 0006777.  ISSN:0012-186X.  PubMed ID 9498640 AN 1998158405    MEDLINE


86.       Huster, W., Shah, A., Kaiser, G., Dere, W., and DiMarchi, R.  (1999).  Statistical and Operational Issues Arising in an Interim Analysis when the Study will Continue. Drug Information Journal, 33, 869-875.

87.       Bolli, G. B.; DiMarchi, R. D.; Park, G. D.; Pramming, S.; Koivisto, V. A.   Insulin analogues and their potential in the management of diabetes mellitus.    Diabetologia  (1999),  42(10),  1151-1167.  CODEN: DBTGAJ  ISSN:0012-186X.  CAN 131:252645  AN 1999:628543    CAPLUS
           
88.       Zhang Faming; Chen Yanyun; Heiman Mark; Dimarchi Richard   Leptin: structure, function and biology.    Vitamins and hormones  (2005),  71 345-72.  Journal code: 0413601.  ISSN:0083-6729.  PubMed ID 16112274 AN 2005447326    MEDLINE

89.       Mayer, John P.; Hsiung, Hansen M.; Flora, David B.; Edwards, Patrick; Smith, Dennis P.; Zhang, Xing-Yue; Gadski, Robert A.; Heiman, Mark L.; Hertel, JeAnne L.; Emmerson, Paul J.; Husain, Saba; O'Brien, Thomas P.; Kahl, Steven D.; Smiley, David L.; Zhang, Lianshan; DiMarchi, Richard D.; Yan, Liang Zeng.   Discovery of a b -MSH-Derived MC-4R Selective Agonist.    Journal of Medicinal Chemistry  (2005),  48(9),  3095-3098.  CODEN: JMCMAR  ISSN:0022-2623.  CAN 143:19243  AN 2005:310077    CAPLUS

90.       Yang, B. and DiMarchi, R.D. A Novel Approach to Resin-based Cysteine Alkylation (2005) Peptides:     Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 88-89.

91.       DiMarchi, R.D., Han, J., Hoffman, A., Gelfanov, V.M., Kohn, W., Micanovic, R., and Mayer J.P. Synthesis and Biological Assessment of Insulin-Like Analogs with Differential Activity at the Insulin and IGF-1 Receptors (2005) Peptides: Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 231-234.

92.       Smiley, D.L., Boaquan, M., Gelfanov, V.M., and DiMarchi, R.D. Exploration and Elaboration of Reported Insulin Superagonism through Site-Selective Replacement at TyrB26 Peptides (2005) Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 237-238.

93.       Yang, B., Gelfanov, V.M. and DiMarchi, R.D. Synthesis and Biological Assessment of Sulfonic Acid-Based Glucagon Antagonists (2005). Peptides: Chemistry, Structure and Biology, Proceedings of
the XIX American Peptide Symposium, 305-306.

94.        Quan, B., Smiley, D.L., Gelfanov, M.L. and DiMarchi, R.D (2005)..  Site Specific Introduction of Unnatural Amino Acids at Sites Critical to Insulin Receptor Recognition & Biological Activity  (2005) Peptides: Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 311-312.

95.       Yan, L-Y, Flora, D.B., Edwards, P., Smiley, D.L., Emmerson, Hansen, H.H., Gadski, R., Hertel, J.,   Heiman, M.L., P.J., Husain, S., O’Brien, T.P., Kahl, S., Zhang, L., DiMarchi, R.D. and Mayer, J.P.      Disulfide as a Constraint to Build Super Potent and Selective Melanocortin-4 Receptor (MCR4) Agonists
(2005). Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 409-410.

96.       Levy, J.J., Gelfanov, V.M. and DiMarchi, R.D. Optimization of the C-terminal Sequence in Glucagon to Maximize Receptor Affinity Peptides: (2005) Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 547-549.

97.       Kohn, W.D., Micanovic, R., Myers, S.L., Vick, A.M., Kahl, S., Zhang, L., Strifler, B., Li, S., Shang, S., Beals, J., Mayer, J.P. and DiMarchi, R.D. pI-shifted Basal Insulin Analogs With High Selectivity for Insulin vs IGF-1 Receptor (2005) Peptides: Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 615-616.

98.       Mayer, John P.; Hsiung, Hansen M.; Flora, David B.; Edwards, Patrick; Smith, Dennis P.; Zhang, Xing-Yue; Gadski, Robert A.; Heiman, Mark L.; Hertel, JeAnne L.; Emmerson, Paul J.; Husain, Saba; O'Brien, Thomas P.; Kahl, Steven D.; Smiley, David L.; Zhang, Lianshan; DiMarchi, Richard D.; Yan, Liang Zeng.  Discovery of a b -MSH-Derived MC-4R Selective Agonist.  (2005) Peptides: Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 655-656.

99.       Gelfanov, V.M., Smiley, D.L, Whittaker, W. and DiMarchi, R.D. Discovery and Structural Optimization of High Affinity Co-Agonists at the Glucagon and GLP-1 Receptors (2005) Peptides: Chemistry, Structure and Biology, Proceedings of the XIX American Peptide Symposium, 763-764.

100.      Yan Liang Z; Flora David; Edwards Patrick; Smiley David L; Emmerson Paul J; Hsiung Hansen M; Gadski Robert; Hertel JeAnne; Heiman Mark L; Husain Saba; O'Brien Thomas P; Kahl Steven D; Zhang Lianshan; DiMarchi Richard D; Mayer John P   Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.    Bioorganic & medicinal chemistry letters  (2005),  15(20),  4611-4.  Journal code: 9107377.  ISSN:0960-894X.  PubMed ID 16105738 AN 2005483034    MEDLINE

101.      Mayer, John P.; DiMarchi, Richard D..   Drugging the Undruggable.    Chemistry & Biology (Cambridge, MA, United States)  (2005),  12(8),  860-861.  CODEN: CBOLE2  ISSN:1074-5521.  AN 2005:903736    CAPLUS

102.      Gabet, Yankel; Mueller, Ralph; Levy, Jay; DiMarchi, Richard; Chorev, Michael; Bab, Itai; Kohavi, David.   Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: a correlative micro-computed tomographic and biomechanical analysis.    Bone (San Diego, CA, United States)  (2006),  39(2),  276-282.  CODEN: BONEDL  ISSN:8756-3282.  AN 2006:563058    CAPLUS
          
103.     DiMarchi, Richard D.  Protein medicinal chemistry, optimization of endocrine hormones.  Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, US, March 26-30, 2006 (2006), MEDI-188.  CODEN: 69HYEC  AN 2006:248340 CAPLUS        

104.     Li, Pengyun; Rogers, Tanya; Smiley, David; Di Marchi, Richard D.; Zhang, Faming.  Design, synthesis and crystallization of a novel glucagon analog as a therapeutic agent.    Acta Crystallographica, Section F: Structural Biology and Crystallization Communications  (2007),  F63(7),  599-601.

105.     Ma, Baoquan; Kang, Wei; Yan, Junkai; Gelfanov, Vasily M.; Smiley, David L.; DiMarchi, Richard D. Elaboration of human insulin superagonism through site-selective replacement at TyrB26.    Zhongguo Shengwu Gongcheng Zazhi  (2007), 27(7), 40-44.

106.     Mayer, John P.; Zhang, Faming; DiMarchi, Richard D.   Insulin structure and function. Biopolymers  (2007),  88(5),  687-713.

107.     Yan, Liang Zeng; Hsiung, Hansen M.; Heiman, Mark L.; Gadski, Robert A.; Emmerson, Paul J.; Hertel, JeAnne; Flora, David; Edwards, Patrick; Smiley, Dave; Zhang, Lianshan; Husain, Saba; Kahl, Steven D.; DiMarchi, Richard D.; Mayer, John P.   Structure-activity relationships of β -MSH derived melanocortin-4 receptor peptide agonists. Current Topics in Medicinal Chemistry (Sharjah, United Arab Emirates)  (2007),  7(11), 1052-1067.
                      
108.     Rubén Nogueiras, Paul Pfluger, Sulay Tovar, Arnold Myrtha, Sharon Mitchell, Amanda Morris, Diego Perez-Tilve, Maria J. Vázquez, Petra Wiedmer, Tamara R. Castañeda, Richard DiMarchi, Matthias Tschöp, Annette Schurmann, Hans-Georg Joost, Lynda M. Williams, Wolfgang Langhans, and Carlos Dieguez Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology (2007) 148(1) 21-26.

109.     Kohn, W.D., Micanovic, R., Myers, S.L., Vick, A.M., Kahl, S., Zhang, L., Strifler, B., Li, S., Shang, S., Beals, J., Mayer, J.P. and DiMarchi, R.D.  pI-shifted Basal Insulin Analogs With Extended in vivo Time Action and Favorable Receptor Selectivity.  Peptides (2007) 28 935-948.

110.     Li, Pengyun; Rogers, Tanya; Smiley, David; DiMarchi, Richard D.; Zhang, Faming. Crystallization and preliminary X-ray analysis of anti-obesity peptide hormone oxyntomodulin.    Protein & Peptide Letters  (2008),  15(2),  232-234


 111.     Cantel, Sonia; Le Chevalier Isaad, Alexandra; Scrima, Mario; Levy, Jay J.; DiMarchi, Richard D.;       Rovero, Paolo; Halperin, Jose A.; D'Ursi, Anna Maria; Papini, Anna Maria; Chorev, Michael.           Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4     intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition. Journal of          Organic Chemistry (2008), 73(15), 5663-5674.


112.      De, Arnab; DiMarchi, Richard D.  Investigation of the feasibility of an amide-based prodrug under physiological conditions.  International Journal of Peptice Research and Therapeutics (2008), 14(4), 393.  CODEN: IJPRFC  ISSN:1573-3149. CAN 150:28712  AN 2008:1460542 CAPLUS


113.      Day, J.; Ottaway, N.; Patterson, J.; Gelfanov, V.; Smiley, D.; Gidda, J.; Findeisen, H.; Bruemmer, D.; Drucker, D.; Chaudhary, N.; Holland, J.; Hembree, J.; Abplanalp, W.; Grant, E., Ruehl; J., Wilson, H.; Kirchner, H.; Haas Lockie, S.; Hofmann, S.; Woods, S.; Nogueiras, R.; Pfluger, P.; Perez-Tilve, D.; DiMarchi, R. and Tschop, M. A new glucagon and GLP-1 co-agonist eliminates obesity in rodents, Nature Chemical Biology (2009), 5(10), 749-757.  CODEN:  NCBABT  ISSN: 1552-4450, CAN 151:305309  AN 2009:851227  CAPLUS


114.      Ma, T.; Day, J.; Gelfanov, V. and DiMarchi, R. Discovery and Structural Optimization of High Affinity Co-Agonists at the Glucagon and GLP-1 Receptors, Proceedings of the 21st American Peptide Society (2009) 146-147.


115.      Day, J.; Patterson, J.; Gelfanov, V. and DiMarchi, Richard Molecular-basis for Specificity in Biological Action at the Homologous Glucagon and GLP-1 Receptors, Proceedings of the 21st American Peptide Society (2009) 142-143.


116.      Finan, B.; Gelfanov, V. and DiMarchi, R. Assessment of a Tat-Derived Peptide as a Vector for Hormonal Transport, Proceedings of the 21st American Peptide Society (2009) 321-322.


117.      De, A. and DiMarchi, R. Synthesis & Analysis of Peptide Hormone-based prodrugs, Proceedings of the 21st American Peptide Society (2009) 160-161.


118.      Ward, B.; Finan, B.; Gelfanov, V. and DiMarchi, R. Exploring the N-terminal Hydrophobic Faces of Glucagon and Glucagon-like Peptide-1, (2009) Proceedings of the 21st American Peptide Society 153-154.


119.      Kukuch, A.; Patterson, J.; DiMarchi, R. and Tolbert, T. Immunoglobulin Fc-based Peptide Fusion Proteins as a Basis for Optimizing In Vivo Pharmacology, (2009) Proceedings of the 21st American Peptide Society 177-178.


120.      Andrews, Z., Erion, E., Beiler, R., Zhong-Wu, L., Abizaid, A., Zigman, J., Elsworth J., Savitt, J., DiMarchi, R., Tschoep, M., Roth, R., Xiao-Bing, G., and Horvath T. (2009) Gherlin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism Journal of Neuroscience 29(45) 14057-65.


121.      Nogueiras, R., Perez-Tilve, D., Veyrat-Dubrebex, C., Morgan, D., Varela, L., Haynes, W., Patterson, J., Disse, E., Pfluger, P., Lopez, M., Woods, S., DiMarchi, R., Diguez, C., Rahmouni, K., Rohner-  Jeanrenaud, F.and Tschöp, M. Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet    induced obesity. JNeurosci (2009), 29(18), 5916-5925.  CODEN:  JNRSDS  ISSN: 0270-6474.     CAN 150:512015  AN 2009”585448  CAPLUS


122.      Ma, Zhen; Cowart, Darin M; Ward, Brian P; Arnold, Randy J; DiMarchi, Richard D; Zhang, Limei; George, Graham N; Scott, Robert A; Giedroc, David P.  Unnatural Amino Acid Substitution as a Probe of the Allosteric Coupling Pathway in a Mycobacterial Cu(l) Sensor.  Journal of the American Chemical Society (2009), 131(50), 18044-18045.  CODEN: JACSAT  ISSN: 0002-7863.  CAN 151:566317  AN 2009:1462185 CAPLUS


123.      Cantel, Sonia; Halperin, Jose A; Chorev, Michael; Scrima, Mario; D’Ursi, Anna M; Levy, Jay J; DiMarchi, Richard D; Le Chevalier, Alexandra; Rovero, Paolo; Papini, Anna M.  Side chain-to-side chain cyclization by intramolecular click reaction—building blocks, solid phase synthesis and conformational characterization.    Advances in experimental medicine and biology (2009), 611 175-6.  Journal code:  0121103.  ISSN: 0065-2598.


124.      Perez-Tilve, D., Nogueiras, R., Pfluger, P.T., Wilson, H., Granholm, N., Arnold, M., Davidson, W.S., DiMarchi, and Tschőp, M.H. Ghrelin promotes nigrostriatal dopamine function and protects it in a redox-dependent manner, JNeurosci (2009), 29(45), 14057-14065.


126.      De, A. and DiMarchi, R. Synthesis & Characterization of Ester-Based Prodrugs of Glucagon-Like Peptide 1, Biopolymers (2010) 94(4) 448-456


127.      Perez-Tilve, D., Hofmann, S.M., Basford, J., Nogueiras, R., Pfluger, P.T., Patterson, J.T., Grant, E., Wilson-Perez, H.,  Granholm, N., Arnold, M.,  Trevasksi, J.L., Butler, A., Davidson, W.S., Woods, S.C., Benoit, S., Sleeman, M.W., DiMarchi, R.D., Hui D.Y., and Tschőp, M.H. Melanocortin signaling in the CNS directly regulates circulating cholesterol (2010) Nature Neuroscience 13, 877-882


128.      Bohrer, B., Li, Y., Reilly, J., Clemmer, D., DiMarchi, R., Radivojac, P., Tang, H. and Arnold, R. (2010) Combinatorial Libraries of Synthetic Peptides as a Model for Shotgun Proteomics Anal. Chem. 82, 6559-6568.


129.      Chabenne, J., DiMarchi Chabenne, M., Gelfanov, V., and DiMarchi, R. Optimization of the Native Glucagon Sequence for Medicinal Purposes Journal of Diabetes Science and Technology (2010), 4(6), 1322-31.


130.      Habegger, K., Heppner, K., Geary, N., Bartness, T., DiMarchi, R. and Tschöp, M. The Metabolic Actions of Glucagon Revisited Nature Reviews Endocrinology (2010), 6(12), 689-97.


131.      Ward, W.Kenneth, Massoud, Ryan G., Szybala, Cory J., Engle, Julia M., Youssef, Joseph El, Carroll, Julie M., Roberts, Charles T., DiMarchi, Richard D. In Vitro and in Vivo Evaluation of Native Glucagon and Glucagon Analog (MAR-D28 during Aging: Lack of Cytotoxicity and Preservation of Hyperglycemic Effect Journal of Diabetes Science and Technology (2010), 4(6), 1311-1321.


132.      Heppner, Kristy M., Habegger, Kirk M., Day, Jonathan, Pfluger, Paul T., Perez-Tilve, Diego, Ward, Brian, Gelfanov, Vasily, Woods, Steve C., DiMarchi, Richard, Tschop, Matthias Glucagon Regulation of Energy Metabolism Physiology & Behavior (2010), 100(5), 545-8.


133.      Day, J., Li, P., Patterson, J., Chabenne, J., DiMarchi Chabenne, M., Gelfanov,. V., and DiMarchi, R. Charge Inversion at Position 68 of the Glucagon and Glucagon-like peptide-1 Receptors Supports Selectivity in Hormone Action, Peptides (2011), 17(3), 218-25.


134.      Patterson , J., Ottaway, N., Gelfanov, V., Smiley, D., Perez-Tilve, D., Pfluger, P., Tschöp, M. and DiMarchi, R. A Novel Human-Based Receptor Antagonist of Sustained Action Reveals Body Weight Control by Endogenous GLP-1, ACS Chemical Biology (2011), 6(2), 135-45.


135.      Wiedmer, Petra, Strasser, Florian, Horvath, Tamas L., Blum, David, DiMarchi, Richard, Lutz, Thomas, Schurmann, Annette, Joost, Hans-Georg, Tschop, Matthias H., Tong, Jenny Ghrelin-induced hypothermia:  A Physiological Basis but No Clinical Risk Physiol. Behav. (2011) 105(1) 43-51.


136.      Patterson , J., Day, J.W., Gelfanov, V. and DiMarchi, R. Functional association of the N-terminal residues with the central region in glucagon-related peptides, Journal of Peptide Science (2011) 17(10) 659-666.


137.      Cho H., Daniel T., Buechler Y.J., Litzinger D.C., Maio Z., Putnam A.M., Kraynov V.S., Sim B.C., Bussell S., Javahishvili T., Kaphle S., Viramontes G., Ong M., Chu S., Becky G.C., Lieu R., Knudsen N., Castiglioni P., Norman T.C., Axelrod D.W., Hoffman A.R., Schultz P.G., DiMarchi R.D., Kimmel B.E. Optimized clinical performance of growth hormone with an expanded genetic code, Proc Natl Acad Sci U S A. 2011 108(22) 9060-5.


138.      Mu J., Pinkstaff J., Li Z., Skidmore L., Li N., Myler H., Dallas-Yang Q., Putnam A.M., Yao J., Bussell S., Wu M., Norman T.C., Rodriguez C.G., Kimmel B., Metzger J.M., Manibusan A., Lee D., Zaller D.M., Zhang B.B., DiMarchi R.D., Berger J.P., Axelrod D.W. FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents, Diabetes. 2011 Dec 30. [Epub ahead of print]