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The bacterial tmRNA is so-named for its dual tRNA-like and mRNA-like nature. (It is also known as 10Sa RNA or SsrA). tmRNA engages in a remarkable trans-translation process, adding a C-terminal peptide tag to the unfinished protein a stalled ribosome. The tmRNA-directed tag targets the unfinished protein for proteolysis.
tmRNA gene sequences have been identified in all completely sequenced bacterial genomes (in 17 of 20 phyla) and in certain phage, mitochondrial and plastidial genomes, but not (yet!) in archaeal or eukaryotic nuclear genomes
Last Updated: 15-Feb-2006
Contains 632 sequences,
from 514 species (81 uncultured)
RNA Webring:
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