Micro and Nanofluidics Our research focuses on the development of microfabricated instrumentation and application in various chemical and biochemical problems. Microfluidic Separations Cell Based Studies Fundamental Characteristics Nanofluidic Sensing Microfluidics High-Efficiency Electrophoretic Analysis of N-Glycans. 2-Dimensional Separations in Planar (left) and Serial-to-Parallel (right) configurations for High Peak Capacities. Nanopores Design and characterization of in-plane and out-of-plane nanofluidic devices. An SEM image (left) and AFM image (right) of a 20° tapered nanofunnel formed by electron beam lithography. Bacteria Cell-based assays performed on microfluidic devices to study chemotaxis, adhesion, and motility of Caulobacter crescentus. Tracking of live cells by video microscopy. Sensing Resistive-pulse sensing of virus capsids by conical nanopores. Current histograms of T=3 (31 nm diameter) and T=4 (36 nm diameter) virus capsids.